In:
International Journal of Cancer, Wiley, Vol. 145, No. 9 ( 2019-11), p. 2468-2477
Abstract:
What's new? Epstein–Barr virus (EBV) and Kaposi's sarcoma‐associated herpesvirus (KSHV) infections are prevalent in sub‐Saharan Africa. However, the pathogenesis of cancers associated with these viruses is not well understood. Why do some people develop these cancers while most don't? In this study of Kaposi's sarcoma (KS), EBV and KSHV showed distinctive patterns of detection and viral load in cases vs . controls, and in HIV‐infected vs . uninfected participants. The results suggest that complex exposure “landscapes,” including the two viruses, HIV, and other exposures such as parasitic coinfections, may modulate the risk of KS and other cancers in sub‐Saharan Africa.
Type of Medium:
Online Resource
ISSN:
0020-7136
,
1097-0215
Language:
English
Publisher:
Wiley
Publication Date:
2019
detail.hit.zdb_id:
218257-9
detail.hit.zdb_id:
1474822-8
Bookmarklink