In:
Journal of Arrhythmia, Wiley, Vol. 32, No. 6 ( 2016-12), p. 486-490
Abstract:
The choice of cardiac resynchronization therapy device, with (CRT‐D) or without (CRT‐P) a defibrillator, in patients with heart failure largely depends on the physician's discretion, because it has not been established which subjects benefit most from a defibrillator. Methods We examined the annual trend of CRT device implantations between 2006 and 2014, and evaluated the factors related to the device selection (CRT‐D or CRT‐P) for primary prevention of sudden cardiac death in patients with heart failure by analyzing the Japan Cardiac Device Treatment Registry (JCDTR) database from January 2011 and August 2015 (CRT‐D, n =2714; CRT‐P, n =555). Results The proportion of CRT‐D implantations for primary prevention among all the CRT‐D recipients was more than 70% during the study period. The number of CRT‐D implantations for primary prevention reached a maximum in 2011 and decreased gradually between 2011 and 2014, whereas CRT‐P implantations increased year by year until 2011 and remained unchanged in recent years. Multivariate analysis identified age (odds ratio [OR] 0.92, 95% confidence interval [CI] 0.90–0.95, P 〈 0.0001), male sex (OR 1.99, 95% CI 1.28–3.11, P 〈 0.005), reduced left ventricular ejection fraction (LVEF) (OR 0.96, 95% CI 0.94–0.98, P 〈 0.0001), and non‐sustained ventricular tachycardia (NSVT) (OR 2.85, 95% CI 1.87–4.35, P 〈 0.0001) as independent factors favoring the choice of CRT‐D. Conclusions Younger age, male sex, reduced LVEF, and a history of NSVT were independently associated with the choice of CRT‐D for primary prevention of sudden cardiac death in patients with heart failure in Japan.
Type of Medium:
Online Resource
ISSN:
1880-4276
,
1883-2148
DOI:
10.1016/j.joa.2016.04.002
Language:
English
Publisher:
Wiley
Publication Date:
2016
detail.hit.zdb_id:
2696593-8
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