In:
Journal of Applied Toxicology, Wiley, Vol. 36, No. 6 ( 2016-06), p. 815-826
Abstract:
The influence of 17β‐estradiol (E2) on estrogen receptor and cytokine gene expression, leukocyte populations and phagocytic activity was assessed in the juvenile sea bass ( Dicentrarchus labrax ) head kidney during organ regionalization from 98 to 239 dph. E2 exposure, beginning at 90 dph resulted in indirect and delayed modifications of interleukin 1β and estrogen receptor α gene expression, which may affect B‐lymphocyte proliferation. The E2 treatment of 120 dph fish led to an increase in estrogen receptor β2 and a decrease in transforming growth factor β1 gene expression, which coincided with decreased phagocytic activity of head kidney lymphocytes and monocytes/macrophages.
Type of Medium:
Online Resource
ISSN:
0260-437X
,
1099-1263
Language:
English
Publisher:
Wiley
Publication Date:
2016
detail.hit.zdb_id:
1475015-6
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