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Supplementary material 9 from: de Jong Y, Kouwenberg J, Boumans L, Hussey C, Hyam R, Nicolson N, Kirk P, Paton A, Michel E, Guiry MD, Boegh PS, Pedersen HÆ, Enghoff H, von Raab-Straube E, Güntsch A, Geoffroy M, Müller A, Kohlbecker A, Berendsohn W, Appeltans W, Arvanitidis C, Vanhoorne B, Declerck J, Vandepitte L, Hernandez F, Nash R, Costello MJ, Ouvrard D, Bezard-Falgas P, Bourgoin T, Wetzel FT, Glöckler F, Korb G, Ring C, Hagedorn G, Häuser C, Aktaç N, Asan A, Ardelean A, Borges PAV, Dhora D, Khachatryan H, Malicky M, Ibrahimov S, Tuzikov A, De Wever A, Moncheva S, Spassov N, Chobot K, Popov A, Boršić I, Sfenthourakis S, Kõljalg U, Uotila P, Gargominy O, Dauvin J-C, Tarkhnishvili D, Chaladze G, Tuerkay M, Legakis A, Peregovits L, Gudmundsson G, Ólafsson E, Lysaght L, Galil BS, Raimondo FM, Domina G, Stoch F, Minelli A, Spungis V, Budrys E, Olenin S, Turpel A, Walisch T, Krpach V, Gambin MT, Ungureanu L, Karaman G, Kleukers RM.J.C, Stur E, Aagaard K, Valland N, Moen TL, Bogdanowicz W, Tykarski P, Węsławski JM, Kędra M, M. de Frias Martins A, Abreu AD, Silva R, Medvedev S, Ryss A, Šimić S, Marhold K, Stloukal E, Tome D, Ramos MA, Valdés B, Pina F, Kullander S, Telenius A, Gonseth Y, Tschudin P, Sergeyeva O, Vladymyrov V, Rizun VB, Raper C, Lear D, Stoev P, Penev L, Rubio AC, Backeljau T, Saarenmaa H, Ulenberg S (2015) PESI - a taxonomic backbone for Europe. Biodiversity Data Journal 3: e5848. https://doi.org/10.3897/BDJ.3.e5848

de Jong, Yde ; Kouwenberg, Juliana ; Boumans, Louis ; [et al.]

Pensoft Publishers ; 2015

In: Biodiversity Data Journal Vol. 3 ( 2015-09-28)

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In: Biodiversity Data Journal, Pensoft Publishers, Vol. 3 ( 2015-09-28)

Abstract: Reliable taxonomy underpins communication in all of biology, not least nature conservation and sustainable use of ecosystem resources. The flexibility of taxonomic interpretations, however, presents a serious challenge for end-users of taxonomic concepts. Users need standardised and continuously harmonised taxonomic reference systems, as well as high-quality and complete taxonomic data sets, but these are generally lacking for non-specialists. The solution is in dynamic, expertly curated web-based taxonomic tools. The Pan-European Species-directories Infrastructure (PESI) worked to solve this key issue by providing a taxonomic e-infrastructure for Europe. It strengthened the relevant social (expertise) and information (standards, data and technical) capacities of five major community networks on taxonomic indexing in Europe, which is essential for proper biodiversity assessment and monitoring activities. The key objectives of PESI were: 1) standardisation in taxonomic reference systems, 2) enhancement of the quality and completeness of taxonomic data sets and 3) creation of integrated access to taxonomic information. This paper describes the results of PESI and its future prospects, including the involvement in major European biodiversity informatics initiatives and programs.

Type of Medium: Online Resource

ISSN: 1314-2828 , 1314-2836

URL: Article

DOI: 10.3897/BDJ.3.e5848

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Language: Unknown

Publisher: Pensoft Publishers

Publication Date: 2015

detail.hit.zdb_id: 2736709-5

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Evaluation of crowdsourced mortality prediction models as a framework for assessing artificial intelligence in medicine

Bergquist, Timothy ; Schaffter, Thomas ; Yan, Yao ; [et al.]

Oxford University Press (OUP) ; 2023

In: Journal of the American Medical Informatics Association ( 2023-08-18)

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In: Journal of the American Medical Informatics Association, Oxford University Press (OUP), ( 2023-08-18)

Abstract: Applications of machine learning in healthcare are of high interest and have the potential to improve patient care. Yet, the real-world accuracy of these models in clinical practice and on different patient subpopulations remains unclear. To address these important questions, we hosted a community challenge to evaluate methods that predict healthcare outcomes. We focused on the prediction of all-cause mortality as the community challenge question. Materials and methods Using a Model-to-Data framework, 345 registered participants, coalescing into 25 independent teams, spread over 3 continents and 10 countries, generated 25 accurate models all trained on a dataset of over 1.1 million patients and evaluated on patients prospectively collected over a 1-year observation of a large health system. Results The top performing team achieved a final area under the receiver operator curve of 0.947 (95% CI, 0.942-0.951) and an area under the precision-recall curve of 0.487 (95% CI, 0.458-0.499) on a prospectively collected patient cohort. Discussion Post hoc analysis after the challenge revealed that models differ in accuracy on subpopulations, delineated by race or gender, even when they are trained on the same data. Conclusion This is the largest community challenge focused on the evaluation of state-of-the-art machine learning methods in a healthcare system performed to date, revealing both opportunities and pitfalls of clinical AI.

Type of Medium: Online Resource

ISSN: 1067-5027 , 1527-974X

URL: Article

DOI: 10.1093/jamia/ocad159

Language: English

Publisher: Oxford University Press (OUP)

Publication Date: 2023

detail.hit.zdb_id: 2018371-9

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Burden and Timeline of Infectious Diseases in the First Year After Solid Organ Transplantation in the Swiss Transplant Cohort Study

van Delden, Christian ; Stampf, Susanne ; Hirsch, Hans H ; [et al.]

Oxford University Press (OUP) ; 2020

In: Clinical Infectious Diseases Vol. 71, No. 7 ( 2020-10-23), p. e159-e169

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In: Clinical Infectious Diseases, Oxford University Press (OUP), Vol. 71, No. 7 ( 2020-10-23), p. e159-e169

Abstract: The burden and timeline of posttransplant infections are not comprehensively documented in the current era of immunosuppression and prophylaxis. Methods In this prospective study nested within the Swiss Transplant Cohort Study (STCS), all clinically relevant infections were identified by transplant–infectious diseases physicians in persons receiving solid organ transplant (SOT) between May 2008 and December 2014 with ≥12 months of follow-up. Results Among 3541 SOT recipients, 2761 (1612 kidney, 577 liver, 286 lung, 213 heart, and 73 kidney-pancreas) had ≥12 months of follow-up; 1520 patients (55%) suffered 3520 infections during the first year posttransplantation. Burden and timelines of clinically relevant infections differed between transplantations. Bacteria were responsible for 2202 infections (63%) prevailing throughout the year, with a predominance of Enterobacteriaceae (54%) as urinary pathogens in heart, lung, and kidney transplant recipients, and as digestive tract pathogens in liver transplant recipients. Enterococcus spp (20%) occurred as urinary tract pathogens in kidney transplant recipients and as digestive tract pathogens in liver transplant recipients, and Pseudomonas aeruginosa (9%) in lung transplant recipients. Among 1039 viral infections, herpesviruses predominated (51%) in kidney, liver, and heart transplant recipients. Among 263 fungal infections, Candida spp (60%) prevailed as digestive tract pathogens in liver transplant recipients. Opportunistic pathogens, including Aspergillus fumigatus (1.4%) and cytomegalovirus (6%), were rare, scattering over 12 months across all SOT recipients. Conclusions In the current era of immunosuppression and prophylaxis, SOT recipients experience a high burden of infections throughout the first year posttransplantation, with rare opportunistic pathogens and a predominance of bacteria.

Type of Medium: Online Resource

ISSN: 1058-4838 , 1537-6591

URL: Article

DOI: 10.1093/cid/ciz1113

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Language: English

Publisher: Oxford University Press (OUP)

Publication Date: 2020

detail.hit.zdb_id: 2002229-3

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Abstract

Mache, Ch. ; PEG Interventional Antimicrobial Strategy Study Group ; Urban, Ch. ; [et al.]

Springer Science and Business Media LLC ; 1992

In: Annals of Hematology Vol. 65, No. S1 ( 1992-1), p. A1-A146

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In: Annals of Hematology, Springer Science and Business Media LLC, Vol. 65, No. S1 ( 1992-1), p. A1-A146

Type of Medium: Online Resource

ISSN: 0939-5555 , 1432-0584

URL: Article

DOI: 10.1007/BF02044602

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 1992

detail.hit.zdb_id: 1458429-3

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A new calibration method for charm jet identification validated with proton-proton collision events at √s = 13 TeV

Tumasyan, Armen ; Adam, Wolfgang ; Andrejkovic, Janik Walter ; [et al.]

IOP Publishing ; 2022

In: Journal of Instrumentation Vol. 17, No. 03 ( 2022-03-01), p. P03014-

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In: Journal of Instrumentation, IOP Publishing, Vol. 17, No. 03 ( 2022-03-01), p. P03014-

Abstract: Many measurements at the LHC require efficient identification of heavy-flavour jets, i.e. jets originating from bottom (b) or charm (c) quarks. An overview of the algorithms used to identify c jets is described and a novel method to calibrate them is presented. This new method adjusts the entire distributions of the outputs obtained when the algorithms are applied to jets of different flavours. It is based on an iterative approach exploiting three distinct control regions that are enriched with either b jets, c jets, or light-flavour and gluon jets. Results are presented in the form of correction factors evaluated using proton-proton collision data with an integrated luminosity of 41.5 fb -1 at √s = 13 TeV, collected by the CMS experiment in 2017. The closure of the method is tested by applying the measured correction factors on simulated data sets and checking the agreement between the adjusted simulation and collision data. Furthermore, a validation is performed by testing the method on pseudodata, which emulate various mismodelling conditions. The calibrated results enable the use of the full distributions of heavy-flavour identification algorithm outputs, e.g. as inputs to machine-learning models. Thus, they are expected to increase the sensitivity of future physics analyses.

Type of Medium: Online Resource

ISSN: 1748-0221

URL: Article

DOI: 10.1088/1748-0221/17/03/P03014

Language: Unknown

Publisher: IOP Publishing

Publication Date: 2022

detail.hit.zdb_id: 2235672-1

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Endovascular thrombectomy for acute ischaemic stroke with established large infarct: multicentre, open-label, randomised trial

Bendszus, Martin ; Fiehler, Jens ; Subtil, Fabien ; [et al.]

Elsevier BV ; 2023

In: The Lancet Vol. 402, No. 10414 ( 2023-11), p. 1753-1763

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In: The Lancet, Elsevier BV, Vol. 402, No. 10414 ( 2023-11), p. 1753-1763

Type of Medium: Online Resource

ISSN: 0140-6736

URL: Article

DOI: 10.1016/S0140-6736(23)02032-9

RVK:

XA 10000

Language: English

Publisher: Elsevier BV

Publication Date: 2023

detail.hit.zdb_id: 2067452-1

detail.hit.zdb_id: 3306-6

detail.hit.zdb_id: 1476593-7

SSG: 5,21

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Sunday, 26 August 2012

Kobayashi, J. ; Yoshida, M. ; Tarui, S. ; [et al.]

Oxford University Press (OUP) ; 2012

In: European Heart Journal Vol. 33, No. suppl 1 ( 2012-08-02), p. 19-338

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In: European Heart Journal, Oxford University Press (OUP), Vol. 33, No. suppl 1 ( 2012-08-02), p. 19-338

Type of Medium: Online Resource

ISSN: 0195-668X , 1522-9645

URL: Article

DOI: 10.1093/eurheartj/ehs281

Language: English

Publisher: Oxford University Press (OUP)

Publication Date: 2012

detail.hit.zdb_id: 2001908-7

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Effect of Celecoxib vs Placebo as Adjuvant Therapy on Disease-Free Survival Among Patients With Breast Cancer : The REACT Randomized Clinical Trial

Coombes, R. Charles ; Tovey, Holly ; Kilburn, Lucy ; [et al.]

American Medical Association (AMA) ; 2021

In: JAMA Oncology Vol. 7, No. 9 ( 2021-09-01), p. 1291-

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In: JAMA Oncology, American Medical Association (AMA), Vol. 7, No. 9 ( 2021-09-01), p. 1291-

Type of Medium: Online Resource

ISSN: 2374-2437

URL: Article

DOI: 10.1001/jamaoncol.2021.2193

Language: English

Publisher: American Medical Association (AMA)

Publication Date: 2021

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Antibody Response After Third Vaccination With mRNA-1273 or BNT162b2: Extension of a Randomized Controlled SARS-CoV-2 Noninferiority Vaccine Trial in Patients With Different Levels of Immunosuppression (COVERALL-2)

Griessbach, Alexandra ; Chammartin, Frédérique ; Abela, Irene A ; [et al.]

Oxford University Press (OUP) ; 2023

In: Open Forum Infectious Diseases Vol. 10, No. 4 ( 2023-04-04)

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In: Open Forum Infectious Diseases, Oxford University Press (OUP), Vol. 10, No. 4 ( 2023-04-04)

Abstract: Extension of the COVERALL (COrona VaccinE tRiAL pLatform) randomized trial showed noninferiority in antibody response of the third dose of Moderna mRNA-1273 vaccine (95.3% [95% confidence interval {CI}, 91.9%–98.7%]) compared to Pfizer-BioNTech BNT162b2 vaccine (98.1% [95% CI, 95.9%–100.0%] ) in individuals with different levels of immunosuppression (difference, −2.8% [95% CI, −6.8% to 1.3%] ).

Type of Medium: Online Resource

ISSN: 2328-8957

URL: Article

DOI: 10.1093/ofid/ofad150

Language: English

Publisher: Oxford University Press (OUP)

Publication Date: 2023

detail.hit.zdb_id: 2757767-3

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Cohort Profile Update: The Swiss Inflammatory Bowel Disease Cohort Study (SIBDCS)

Pittet, Valérie ; Michetti, Pierre ; Mueller, Christoph ; [et al.]

Oxford University Press (OUP) ; 2019

In: International Journal of Epidemiology Vol. 48, No. 2 ( 2019-04-01), p. 385-386f

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In: International Journal of Epidemiology, Oxford University Press (OUP), Vol. 48, No. 2 ( 2019-04-01), p. 385-386f

Type of Medium: Online Resource

ISSN: 0300-5771 , 1464-3685

URL: Article

DOI: 10.1093/ije/dyy298

RVK:

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Language: English

Publisher: Oxford University Press (OUP)

Publication Date: 2019

detail.hit.zdb_id: 1494592-7

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