In:
Revista de Odontologia da Universidade de São Paulo, FapUNIFESP (SciELO), Vol. 12, No. 3 ( 1998-07), p. 207-213
Abstract:
We compared levels of sera immunoglobulin IgG and IgA, and salivary IgG and secretory IgA (IgA-S) reactive to Actinobacillus actinomycetemcomitans (Aa). Doses of total sera IgM, IgG, and IgA of patients with early-onset (EOP) and adult (AP) periodontitis, and healthy controls without periodontal disease were assessed. Igs to Aa were determined by ELISA. Total sera Igs were quantified by simple radial immunodiffusion, using a mixture of sonicated extracts of five isolates obtained from EOP patients confirmed as Aa, and sonicated extract of Aa reference strain FDC Y4 as antigens. No significant differences were found between sera IgG and IgA and salivary IgG and IgA-S levels among groups EOP (n=9), AP (n=20), and control (n=20). These results suggest that there was no significant alteration of the Aa humoral immune response level in patients with periodontitis. By quantification of total sera Igs, we found no statistically significant differences between EOP (n=9) and AP (n=9) patients or healthy controls (n=9).
Type of Medium:
Online Resource
ISSN:
0103-0663
DOI:
10.1590/S0103-06631998000300003
Language:
Unknown
Publisher:
FapUNIFESP (SciELO)
Publication Date:
1998
detail.hit.zdb_id:
2031051-1
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