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Meiotic Recombination in Human Oocytes

Cheng, Edith Y. ; Hunt, Patricia A. ; Naluai-Cecchini, Theresa A. ; [et al.]

Public Library of Science (PLoS) ; 2009

In: PLoS Genetics Vol. 5, No. 9 ( 2009-9-18), p. e1000661-

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In: PLoS Genetics, Public Library of Science (PLoS), Vol. 5, No. 9 ( 2009-9-18), p. e1000661-

Type of Medium: Online Resource

ISSN: 1553-7404

URL: Article

DOI: 10.1371/journal.pgen.1000661

DOI: 10.1371/journal.pgen.1000661.g001

DOI: 10.1371/journal.pgen.1000661.g002

DOI: 10.1371/journal.pgen.1000661.g003

DOI: 10.1371/journal.pgen.1000661.g004

DOI: 10.1371/journal.pgen.1000661.g005

DOI: 10.1371/journal.pgen.1000661.g006

DOI: 10.1371/journal.pgen.1000661.g007

DOI: 10.1371/journal.pgen.1000661.g008

DOI: 10.1371/journal.pgen.1000661.g009

DOI: 10.1371/journal.pgen.1000661.t001

DOI: 10.1371/journal.pgen.1000661.t002

DOI: 10.1371/journal.pgen.1000661.t003

DOI: 10.1371/journal.pgen.1000661.t004

DOI: 10.1371/journal.pgen.1000661.t005

DOI: 10.1371/journal.pgen.1000661.t006

DOI: 10.1371/journal.pgen.1000661.s001

DOI: 10.1371/journal.pgen.1000661.s002

DOI: 10.1371/journal.pgen.1000661.s003

DOI: 10.1371/journal.pgen.1000661.s004

DOI: 10.1371/journal.pgen.1000661.s005

DOI: 10.1371/journal.pgen.1000661.s006

DOI: 10.1371/journal.pgen.1000661.s007

Language: English

Publisher: Public Library of Science (PLoS)

Publication Date: 2009

detail.hit.zdb_id: 2186725-2

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Integrative functional genomic analysis of human brain development and neuropsychiatric risks

Li, Mingfeng ; Santpere, Gabriel ; Imamura Kawasawa, Yuka ; [et al.]

American Association for the Advancement of Science (AAAS) ; 2018

In: Science Vol. 362, No. 6420 ( 2018-12-14)

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In: Science, American Association for the Advancement of Science (AAAS), Vol. 362, No. 6420 ( 2018-12-14)

Abstract: To broaden our understanding of human neurodevelopment, we profiled transcriptomic and epigenomic landscapes across brain regions and/or cell types for the entire span of prenatal and postnatal development. Integrative analysis revealed temporal, regional, sex, and cell type–specific dynamics. We observed a global transcriptomic cup-shaped pattern, characterized by a late fetal transition associated with sharply decreased regional differences and changes in cellular composition and maturation, followed by a reversal in childhood-adolescence, and accompanied by epigenomic reorganizations. Analysis of gene coexpression modules revealed relationships with epigenomic regulation and neurodevelopmental processes. Genes with genetic associations to brain-based traits and neuropsychiatric disorders (including MEF2C , SATB2 , SOX5 , TCF4 , and TSHZ3 ) converged in a small number of modules and distinct cell types, revealing insights into neurodevelopment and the genomic basis of neuropsychiatric risks.

Type of Medium: Online Resource

ISSN: 0036-8075 , 1095-9203

URL: Article

DOI: 10.1126/science.aat7615

RVK:

TA 1000

RVK:

WA 15000

Language: English

Publisher: American Association for the Advancement of Science (AAAS)

Publication Date: 2018

detail.hit.zdb_id: 128410-1

detail.hit.zdb_id: 2066996-3

detail.hit.zdb_id: 2060783-0

SSG: 11

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Transcriptional landscape of the prenatal human brain

Miller, Jeremy A. ; Ding, Song-Lin ; Sunkin, Susan M. ; [et al.]

Springer Science and Business Media LLC ; 2014

In: Nature Vol. 508, No. 7495 ( 2014-4), p. 199-206

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In: Nature, Springer Science and Business Media LLC, Vol. 508, No. 7495 ( 2014-4), p. 199-206

Type of Medium: Online Resource

ISSN: 0028-0836 , 1476-4687

URL: Article

DOI: 10.1038/nature13185

RVK:

TA 1000

RVK:

UA 1000

RVK:

WA 15000

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2014

detail.hit.zdb_id: 120714-3

detail.hit.zdb_id: 1413423-8

SSG: 11

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Differences in Oral Structure and Tissue Interactions during Mouse vs. Human Palatogenesis: Implications for the Translation of Findings from Mice

Yu, Kai ; Deng, Mei ; Naluai-Cecchini, Theresa ; [et al.]

Frontiers Media SA ; 2017

In: Frontiers in Physiology Vol. 8 ( 2017-03-15)

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In: Frontiers in Physiology, Frontiers Media SA, Vol. 8 ( 2017-03-15)

Type of Medium: Online Resource

ISSN: 1664-042X

URL: Article

DOI: 10.3389/fphys.2017.00154

Language: Unknown

Publisher: Frontiers Media SA

Publication Date: 2017

detail.hit.zdb_id: 2564217-0

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