In:
Spektrum der Augenheilkunde, Springer Science and Business Media LLC, Vol. 36, No. 6 ( 2022-12), p. 139-144
Abstract:
Dry eye (DE) is a multifactorial disease of the ocular surface, which may be a result of insufficient production of tear fluid or inadequate composition of the tear film with increased evaporation. An important diagnostic parameter of DE is the tear film break-up time (BUT). The aim of this study was to provide a comparison between the non-invasive keratography BUT (NIK-BUT) and the fluorescein break-up time (F-BUT) as well as to assess the correlation with patients’ subjective complaints. Material and methods In this study 271 patients (212 women, 59 men, aged 19–91 years, average age 59.1 years) with DE, underwent an ocular surface examination including NIK-BUT and F‑BUT in the DE unit of the University Eye Hospital, Medical University of Graz. The NIK-BUT was assessed using the Oculus Keratograph 5M. We documented both the first and the average NIK-BUT. Then, a standardized F‑BUT measurement was done. The subjective complaints of the patients were assessed using the ocular surface disease index (OSDI®) and a visual analogue scale (VAS). Results The values of the first and average NIK-BUT correlated significantly with the F‑BUT. The NIK-BUT values were significantly longer than the F‑BUT values ( p 〈 0.001). The average NIK-BUT values correlated with subjective symptoms (VAS) but F‑BUT did not show a correlation with subjective sensation. Conclusion The average NIK-BUT values correlated better with the subjective sensation of the patients with DE than F‑BUT values; however, there was a poor correlation. Further studies are needed to clarify the role of non-invasive BUT, especially its relation to the different subtypes of dry eye.
Type of Medium:
Online Resource
ISSN:
0930-4282
,
1613-7523
DOI:
10.1007/s00717-022-00525-w
Language:
German
Publisher:
Springer Science and Business Media LLC
Publication Date:
2022
detail.hit.zdb_id:
2010368-2
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