In:
American Journal of Physiology-Legacy Content, American Physiological Society, Vol. 197, No. 1 ( 1959-07-01), p. 201-204
Abstract:
In anesthetized open-chest dogs, the mean blood pressure, cardiac output and coronary sinus flow were measured before and after opening of a unilateral or bilateral femoral arteriovenous fistulae. The opening of an A-V fistula was accompanied by a decrease in mean blood pressure and an increase in cardiac output and coronary sinus flow. Approximately 20 seconds after the fistula was opened, the coronary sinus flow established itself at a level independent of the per cent change in mean blood pressure and cardiac output. Opening of an arteriovenous fistula was also followed by a significant increase in myocardial oxygen consumption, work, and in most experiments by an increase in cardiac efficiency. During periods of opened-fistula the augmented myocardial oxygen consumption was accompanied by a spread of the arterial-coronary sinus oxygen difference.
Type of Medium:
Online Resource
ISSN:
0002-9513
DOI:
10.1152/ajplegacy.1959.197.1.201
Language:
English
Publisher:
American Physiological Society
Publication Date:
1959
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SSG:
12
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