In:
Archives of Gynecology and Obstetrics, Springer Science and Business Media LLC, Vol. 306, No. 3 ( 2021-11-18), p. 585-592
Abstract:
Treatment of mid-trimester classic preterm premature rupture of membranes ( PPROM) with systemic antibiotics has limited success in the prevention of chorioamnionitis, funisitis and fetal inflammatory response syndrome because of very low transplacental passage. Methods Here we report a case of PPROM at 18 weeks gestation with anhydramnion colonized by multi-resistant Escherichia coli ( E. coli ). A catheter system was implanted at 23/2nd weeks gestation, enabling long-term continuous lavage of the amniotic cavity with Amnion Flush Solution (100 ml/h combined with intraamniotic meropenem application). Results The patient gave birth to a preterm male infant at 28/3rd without any signs of infection. In a follow-up examination at 24 months, there was no neurological disturbance or developmental delay. Conclusion The classic PPROM with multi-resistant E. coli colonization could be treated with continuous amnioinfusion and meropenem.
Type of Medium:
Online Resource
ISSN:
1432-0711
DOI:
10.1007/s00404-021-06319-w
Language:
English
Publisher:
Springer Science and Business Media LLC
Publication Date:
2021
detail.hit.zdb_id:
1458450-5
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