In:
International Journal of Urology, Wiley, Vol. 12, No. 2 ( 2005-02), p. 204-207
Abstract:
Abstract Epithelioid angiomyolipoma is a recently recognized variant of angiomyolipoma, which is characterized by the presence of polygonal cells with densely eosinophilic cytoplasm and varying degrees of nuclear atypia. Only a relatively small number of cases of epithelioid angiomyolipoma of the kidney have been reported in the literature. We report a case of epithelioid angiomyolipoma of the kidney that occurred in a 38‐year‐old woman. The tumor was composed of diffuse sheets of epithelioid cells, adipocytes and only scattered thick‐walled blood vessels. The epithelioid cells had pleomorphic and hyperchromatic nuclei with densely eosinophilic cytoplasm. Hemorrhage, necrotic foci and clusters of foamy macrophages were present. HMB‐45, CD117 (c‐kit) and CD68 were detected in the epithelioid cells. There was no expression of cytokeratin, epithelial membrane antigen or desmin. The patient showed no evidence of recurrence or metastatic disease 9 months after nephrectomy.
Type of Medium:
Online Resource
ISSN:
0919-8172
,
1442-2042
DOI:
10.1111/iju.2005.12.issue-2
DOI:
10.1111/j.1442-2042.2005.01003.x
Language:
English
Publisher:
Wiley
Publication Date:
2005
detail.hit.zdb_id:
2009793-1
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