In:
BioMed Research International, Hindawi Limited, Vol. 2015 ( 2015), p. 1-6
Abstract:
Objective . To investigate the outcomes of intracytoplasmic sperm injection (ICSI) cycles where sibling oocytes from a single donor were split between two recipients based on strict sperm morphology. Methods . Retrospective cohort study. All ICSI cycles had one donor’s oocytes split between two recipients in a 1 : 1 ratio based on strict sperm morphology, that is, one male partner had morphology of 0% and the other had morphology of 〉 1%. Fertilization, positive hCG, clinical pregnancy, spontaneous miscarriage, and live birth rates of the aforementioned groups were compared. Results . The baseline characteristics of the two groups ( n = 103 ), including semen parameters of the male partners, were comparable. There was no difference in the fertilization rates when comparing the 0% group to the 〉 1% group (78.7% versus 81.6%; P = 0.66 ). The overall positive hCG, clinical pregnancy, spontaneous miscarriage, and live birth rates for the 0% group were 61.2%, 49.5%, 10.7%, and 38.8%, respectively. The corresponding rates in the 〉 1% group were positive hCG (63.1%), clinical pregnancy (55.3%), spontaneous miscarriage (7.77%), and live birth (46.6%). Conclusions . The fertilization and pregnancy outcomes of ICSI cycles for strict sperm morphology of 0% versus morphology of 〉 1% are equivalent. These results can provide reassurance to couples undergoing ICSI for severe teratospermia.
Type of Medium:
Online Resource
ISSN:
2314-6133
,
2314-6141
Language:
English
Publisher:
Hindawi Limited
Publication Date:
2015
detail.hit.zdb_id:
2698540-8
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