In:
PLOS Genetics, Public Library of Science (PLoS), Vol. 19, No. 8 ( 2023-8-24), p. e1010863-
Abstract:
Quantitative traits may be controlled by many loci, many alleles at each locus, and subject to genotype-by-environment interactions, making them difficult to map. One example of such a complex trait is shoot branching in the model plant Arabidopsis, and its plasticity in response to nitrate. Here, we use artificial selection under contrasting nitrate supplies to dissect the genetic architecture of this complex trait, where loci identified by association mapping failed to explain heritability estimates. We found a consistent response to selection for high branching, with correlated responses in other traits such as plasticity and flowering time. Genome-wide scans for selection and simulations suggest that at least tens of loci control this trait, with a distinct genetic architecture between low and high nitrate treatments. While signals of selection could be detected in the populations selected for high branching on low nitrate, there was very little overlap in the regions selected in three independent populations. Thus the regulatory network controlling shoot branching can be tuned in different ways to give similar phenotypes.
Type of Medium:
Online Resource
ISSN:
1553-7404
DOI:
10.1371/journal.pgen.1010863
DOI:
10.1371/journal.pgen.1010863.g001
DOI:
10.1371/journal.pgen.1010863.g002
DOI:
10.1371/journal.pgen.1010863.g003
DOI:
10.1371/journal.pgen.1010863.g004
DOI:
10.1371/journal.pgen.1010863.g005
DOI:
10.1371/journal.pgen.1010863.s001
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10.1371/journal.pgen.1010863.s002
DOI:
10.1371/journal.pgen.1010863.s003
DOI:
10.1371/journal.pgen.1010863.s004
DOI:
10.1371/journal.pgen.1010863.s005
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10.1371/journal.pgen.1010863.s006
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10.1371/journal.pgen.1010863.s007
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10.1371/journal.pgen.1010863.s008
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10.1371/journal.pgen.1010863.s009
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10.1371/journal.pgen.1010863.s010
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10.1371/journal.pgen.1010863.s011
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10.1371/journal.pgen.1010863.s012
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10.1371/journal.pgen.1010863.s013
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10.1371/journal.pgen.1010863.s014
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10.1371/journal.pgen.1010863.s015
DOI:
10.1371/journal.pgen.1010863.s016
DOI:
10.1371/journal.pgen.1010863.s017
DOI:
10.1371/journal.pgen.1010863.s018
DOI:
10.1371/journal.pgen.1010863.s019
DOI:
10.1371/journal.pgen.1010863.r001
DOI:
10.1371/journal.pgen.1010863.r002
DOI:
10.1371/journal.pgen.1010863.r003
DOI:
10.1371/journal.pgen.1010863.r004
DOI:
10.1371/journal.pgen.1010863.r005
DOI:
10.1371/journal.pgen.1010863.r006
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2023
detail.hit.zdb_id:
2186725-2
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