In:
Journal of Clinical Microbiology, American Society for Microbiology, Vol. 44, No. 1 ( 2006-01), p. 47-50
Abstract:
Markers of Epstein-Barr virus (EBV) infection include measures of specific serological titers and of viral load (VLo) in peripheral blood mononuclear cells. Few studies have investigated the correlation between these two phenotypes. Here, we found that there was no correlation between VLo and either anti-EBV nuclear antigen type 1 or anti-early antigen immunoglobulin G (IgG) titer but that anti-viral capsid antigen (VCA) IgG titer increased with VLo in peripheral blood mononuclear cells in patients with Hodgkin's lymphoma ( P = 3.10 −3 ). A similar pattern was observed in healthy first-degree relatives (parents and siblings) of patients ( P = 6.10 −4 ). Our results indicate that anti-VCA IgG titers and EBV VLo are specifically correlated EBV phenotypes.
Type of Medium:
Online Resource
ISSN:
0095-1137
,
1098-660X
DOI:
10.1128/JCM.44.1.47-50.2006
Language:
English
Publisher:
American Society for Microbiology
Publication Date:
2006
detail.hit.zdb_id:
1498353-9
SSG:
12
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