In:
Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 132, No. suppl_3 ( 2015-11-10)
Abstract:
Introduction: Our study aimed to evaluate the impact of procedure-related cardiac conduction disturbances (CCD) on myocardial performance (standard and speckle-tracking-based LV function parameters) after transfemoral aortic valve implantation (TAVI TF). Hypothesis: New cardiac conduction disturbances after TAVI impair LV function and morphology as well as survival. Methods: Between 2010 and 2013, 168 patients (pts.) underwent TAVI TF using the Core Valve at our institution. 95 of them with complete follow-up (mean follow up 264± 241 days) were evaluated with respect to the presence of new CCD and their effect on myocardial performance. Results: Aortic valve orifice and mean gradient significantly improved (from 0.7 ± 0.2 to 1.8 ± 0.4 cm 2 , p 〈 0.001 and from 42.4 ± 17.7 to 8.3 ± 4.0 mmHg, p 〈 0.001, respectively). After TAVI, 37.9% of pts. presented with new CCDs. Pts. without additional CCDs showed an improvement of left ventricular systolic and diastolic function (LVEF from 43.7 ± 16.5% to 48 ± 16.2%, p= 0.004; E/A-ratio from 1.4 ± 1.0 to 1.0 ± 0.9, p= 0.006), whereas pts. with procedure-related CCDs had a mild LVEF deterioration (from 51.8 ± 13.9% to 47.3 ± 8.5%, p=0.16). Comparison of the changes between groups without and with CCDs revealed significant differences (Table 1). However, on Kaplan Meier analysis survival was not significantly different between both groups (p=0.73). Conclusions: Procedure-related conductions abnormalities after TAVI impair LV function, however in our pt. cohort with no impact on overall survival.
Type of Medium:
Online Resource
ISSN:
0009-7322
,
1524-4539
DOI:
10.1161/circ.132.suppl_3.19135
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2015
detail.hit.zdb_id:
1466401-X
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