In:
ChemBioChem, Wiley, Vol. 6, No. 3 ( 2005-03-04), p. 453-453
Abstract:
The cover picture shows the target discovery process as implemented at Schering AG for work on kinases. Before a target enters the lead discovery phase, the target candidate has to pass several hurdles to maximise the likelihood of achieving target‐selective inhibition by small‐molecule inhibitors. This target‐discovery process comprises three phases: target identification, drugability assessment and functional target validation. Further details can be found in the article of U. Egner et al. on p. 468 ff.
Type of Medium:
Online Resource
ISSN:
1439-4227
,
1439-7633
DOI:
10.1002/cbic.200590008
Language:
English
Publisher:
Wiley
Publication Date:
2005
detail.hit.zdb_id:
2020469-3
SSG:
12
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