In:
The British Journal of Radiology, British Institute of Radiology, Vol. 95, No. 1133 ( 2022-05-01)
Abstract:
Late gadolinium enhancement with fixed short inversion time (LGE short ) provides excellent tissue contrast with dark scar and bright blood pool and does not need prior myocardial nulling. We hypothesize better visibility of ischemic scars and equal visibility of non-ischemic LGE in LGE short compared to clinically established LGE (LGE standard ). Methods LGE short and LGE standard were retrospectively evaluated in 179 patients (3043 segments) with suspected or known coronary artery disease by four blinded readers (reader A: most experienced - D: least experienced). The amount of ischemic and non-ischemic LGE as well as visibility (4: very good – 1: poor) of ischemic LGE was visually assessed. Results All readers detected more infarcted segments in LGE short compared to LGE standard (378 segments reported as infarcted; A:p = 0.5, B:p = 0.8, C,D:p = 0.03). Scar visibility was scored higher in LGE short by all readers (A,B:p = 0.03; C,D:p = 0.02), especially for subendocardial infarcts (A,B:p = 0.04, C,D:p = 0.02). Less experienced readers detected significantly more infarcted papillary muscles (C:p = 0.02, D:p = 0.03) in a shorter reading time in LGE short (C:p = 0.04, D:p = 0.02). Non-ischemic LGE was equally visible in both sequences (A:p = 0.9, B:p = 0.8, C,D:p = 0.6). Conclusions LGE short detects more ischemic LGE with improved scar visibility compared to LGE standard , independent of experience level. The visibility of non-ischemic LGE is equivalent to LGE standard . Less experienced readers can diagnose ischemic and non-ischemic LGE faster in LGE short . Advances in knowledge: LGE short with its maximal operational simplicity can be used for visualization of all types of fibrosis – ischemic and non-ischemic – instead of LGE standard , independent of experience level.
Type of Medium:
Online Resource
ISSN:
0007-1285
,
1748-880X
DOI:
10.1259/bjr.20210966
Language:
English
Publisher:
British Institute of Radiology
Publication Date:
2022
detail.hit.zdb_id:
1468548-6
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