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Detection of Influenza Virus Using a SOI-Nanoribbon Chip, Based on an N-Type Field-Effect Transistor

Malsagova, Kristina A. ; Pleshakova, Tatyana O. ; Kozlov, Andrey F. ; [et al.]

MDPI AG ; 2021

In: Biosensors Vol. 11, No. 4 ( 2021-04-12), p. 119-

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In: Biosensors, MDPI AG, Vol. 11, No. 4 ( 2021-04-12), p. 119-

Abstract: The detection of influenza A virions with a nanoribbon detector (NR detector) has been demonstrated. Chips for the detector have been fabricated based on silicon-on-insulator nanoribbon structures (SOI nanoribbon chip), using a complementary metal-oxide-semiconductor (CMOS)-compatible technology—by means of gas-phase etching and standard optical photolithography. The surface of the SOI nanoribbon chip contains a matrix of 10 nanoribbon (NR) sensor elements. SOI nanoribbon chips of n-type conductance have been used for this study. For biospecific detection of target particles, antibodies against influenza virus have been covalently immobilized onto NRs. Influenza A virus detection was performed by real-time registration of the source-drain current through the NRs. The detection of the target viral particles was carried out in buffer solutions at the target particles concentration within the range from 107 to 103 viral particles per milliliter (VP/mL). The lowest detectable concentration of the target viral particles was 6 × 10−16 M (corresponding to 104 VP/mL). The use of solutions containing ~109 to 1010 VP/mL resulted in saturation of the sensor surface with the target virions. In the saturation mode, detection was impossible.

Type of Medium: Online Resource

ISSN: 2079-6374

URL: Article

DOI: 10.3390/bios11040119

Language: English

Publisher: MDPI AG

Publication Date: 2021

detail.hit.zdb_id: 2662125-3

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The study of texture features for the recognition problems of bone marrow cells in information-measuring systems of oncohematology

Nikitaev, Valentin G. ; Pronichev, Alexander N. ; Tupitsin, Nikolay N. ; [et al.]

FSUE VNIIMS All-Russian Research Institute of Metrological Service ; 2021

In: Izmeritel`naya Tekhnika , No. 10 ( 2021), p. 53-59

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In: Izmeritel`naya Tekhnika, FSUE VNIIMS All-Russian Research Institute of Metrological Service, , No. 10 ( 2021), p. 53-59

Type of Medium: Online Resource

ISSN: 0368-1025

URL: Article

DOI: 10.32446/0368-1025it.2021-10-53-59

Language: Unknown

Publisher: FSUE VNIIMS All-Russian Research Institute of Metrological Service

Publication Date: 2021

detail.hit.zdb_id: 240847-8

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Comparative analysis of machine learning methods for the diagnosis of acute leukemia

Liberis, Kirill A. ; Nikitaev, Valentin G. ; Pronichev, Alexander N.

Publishing House "Polytechnica" ; 2022

In: Biotechnosfera , No. 2 ( 2022), p. 55-58

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In: Biotechnosfera, Publishing House "Polytechnica", , No. 2 ( 2022), p. 55-58

Type of Medium: Online Resource

ISSN: 2073-4824

URL: Article

DOI: 10.25960/bts.2022.2.55

Language: Unknown

Publisher: Publishing House "Polytechnica"

Publication Date: 2022

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Сonvolutional neural networks in the diagnosis of skin neoplasms

Nikitaev, Valentin G. ; Pronichev, Alexander N. ; Tamrazova, Olga B. ; [et al.]

National Research Nuclear University MEPhI (Moscow Engineering Physics Institute) ; 2021

In: Bezopasnost informacionnyh tehnology Vol. 28, No. 4 ( 2021-12)

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In: Bezopasnost informacionnyh tehnology, National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), Vol. 28, No. 4 ( 2021-12)

Type of Medium: Online Resource

ISSN: 2074-7136 , 2074-7128

Uniform Title: СВЕРТОЧНЫЕ НЕЙРОННЫЕ СЕТИ В ДИАГНОСТИКЕ НОВООБРАЗОВАНИЙ КОЖИ

URL: Article

DOI: 10.26583/bit.2021.4.09

Language: Unknown

Publisher: National Research Nuclear University MEPhI (Moscow Engineering Physics Institute)

Publication Date: 2021

detail.hit.zdb_id: 2813556-8

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Comparison of structureless areas recognition models in pigmented skin neoplasms images

Nikitaev, Valentin G. ; Pronichev, Alexander N. ; Kozlov, Vladimir S. ; [et al.]

Publishing House "Polytechnica" ; 2022

In: Biotechnosfera , No. 2 ( 2022), p. 27-32

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In: Biotechnosfera, Publishing House "Polytechnica", , No. 2 ( 2022), p. 27-32

Type of Medium: Online Resource

ISSN: 2073-4824

URL: Article

DOI: 10.25960/bts.2022.2.27

Language: Unknown

Publisher: Publishing House "Polytechnica"

Publication Date: 2022

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System for human medical data processing during radioiodine therapy

Trukhin, Aleksey A. ; Sheremeta, Marina S. ; Slaschuk, Konstantin Yu. ; [et al.]

Publishing House "Polytechnica" ; 2022

In: Biotechnosfera , No. 2 ( 2022), p. 18-26

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In: Biotechnosfera, Publishing House "Polytechnica", , No. 2 ( 2022), p. 18-26

Type of Medium: Online Resource

ISSN: 2073-4824

URL: Article

DOI: 10.25960/bts.2022.2.18

Language: Unknown

Publisher: Publishing House "Polytechnica"

Publication Date: 2022

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