In:
European Journal of Neurology, Wiley, Vol. 14, No. 6 ( 2007-06), p. 706-707
Abstract:
Migraine is a common, genetically influenced neurovascular disorder. The dopamine transporter gene is a candidate for migraine association studies. This study tested a functionally linked variable number tandem repeat (VNTR) in intron 8 of the dopamine transporter gene (DAT Int8 ) in 550 migraine cases (401 with aura, 149 without aura) and 550 non‐migraine controls. Chi‐squared analysis of the DAT Int8 revealed that the allele and genotype frequency distributions for migraine cases (including subtype analysis) and controls were not different ( P 〉 0.1). These findings offer no evidence for an association of the DAT Int8 with migraine with and without aura and therefore do not implicate the dopamine transporter gene as a modifier of migraine risk.
Type of Medium:
Online Resource
ISSN:
1351-5101
,
1468-1331
DOI:
10.1111/ene.2007.14.issue-6
DOI:
10.1111/j.1468-1331.2007.01800.x
Language:
English
Publisher:
Wiley
Publication Date:
2007
detail.hit.zdb_id:
2020241-6
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