In:
Cardiology in the Young, Cambridge University Press (CUP), Vol. 25, No. 7 ( 2015-10), p. 1254-1262
Abstract:
Background: We aimed to assess biatrial size and function, interactions on atrial and ventricular levels, and atrio-ventricular coupling in patients after tetralogy of Fallot repair. Methods: A total of 34 patients with a mean age of 20.9±9 years, and 35 healthy controls, underwent two-dimensional speckle tracking echocardiography for ventricular and atrial strain measurements and real-time three-dimensional echocardiography to assess ventricular and atrial volumes. Results: When compared with controls, tetralogy of Fallot patients had significantly reduced right atrial peak atrial longitudinal strain (p 〈 0.01), right atrial peak atrial contraction strain (p 〈 0.01), right atrial ejection fraction (p 〈 0.01), left atrial peak atrial longitudinal strain (p 〈 0.01), left atrial peak atrial contraction strain (p 〈 0.05), and left atrial ejection fraction (p 〈 0.01). In the tetralogy of Fallot group, left ventricular ejection fraction was negatively related to the right ventricular end-systolic volume normalised to body surface area (r=−0.62, p 〈 0.01). An association was found in patients between the right atrial peak longitudinal strain and mean right ventricular strain (r=0.64, p 〈 0.01). In patients, the left atrial peak longitudinal strain correlated negatively with right atrial end-diastolic volume normalised to body surface area (r=−0.67, p 〈 0.01), whereas the left atrial ejection fraction correlated weakly with left ventricular ejection fraction (r=0.41, p 〈 0.05). Conclusions: In asymptomatic tetralogy of Fallot patients, biatrial dysfunction exists and can be quantified via two-dimensional speckle tracking echocardiography as well as real-time three-dimensional echocardiography. Different forms of interactions on atrial and ventricular levels are evident among such cohorts.
Type of Medium:
Online Resource
ISSN:
1047-9511
,
1467-1107
DOI:
10.1017/S1047951114002108
Language:
English
Publisher:
Cambridge University Press (CUP)
Publication Date:
2015
detail.hit.zdb_id:
2060876-7
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