X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Online Resource
    Online Resource
    Digitalisierung und disruptive Veränderungen der Rheumatologie
    Springer Science and Business Media LLC ; 2023
    In:  Zeitschrift für Rheumatologie Vol. 82, No. 5 ( 2023-06), p. 417-424
    Details
    In: Zeitschrift für Rheumatologie, Springer Science and Business Media LLC, Vol. 82, No. 5 ( 2023-06), p. 417-424
    Abstract: In jüngster Zeit haben sich in vielen Branchen aufgrund des raschen Fortschritts in der Informations- und Kommunikationstechnologie (IKT) disruptive Veränderungen ereignet. Ziel dieser systematischen Literaturrecherche war es, ein erstes Verständnis dafür zu entwickeln, was über neue IKT in der Rheumatologie und ihr disruptives Potenzial bekannt ist. Methoden Die Datenbanken PubMed, LIVIVO und EBSCO Discovery Service (EDS) wurden nach relevanter Literatur durchsucht. Der Einsatz neuer IKT-Technologien wurde identifiziert, kategorisiert und das disruptive Potenzial diskutiert. Dabei wurden Artikel aus den Jahren 2008 bis 2021 in deutscher und englischer Sprache berücksichtigt. Ergebnisse Es wurden 3539 Artikel identifiziert; nach Anwendung von Einschluss- und Ausschlusskriterien wurden 55 Artikel in die Analyse aufgenommen. Die Mehrheit der Artikel (48) verwendete ein nichtexperimentelles Design oder stützte sich auf Expertenmeinungen. Die in diesen Artikeln erwähnten neuen IKT ließen sich 4 Hauptkategorien zuordnen: Technologien, die auf die Entwicklung von neuen Erkenntnissen durch Datenerhebung zielen ( n  = 32); Technologien, die neues Wissen durch die Auswertung von existierenden Daten entwickeln (z. B. durch das Auffinden besserer Behandlungsmöglichkeiten) ( n  = 11); Technologien, die die Vermittlung von vorhandenem Wissen verbessern ( n  = 32); und Technologien, die den Versorgungsprozess verbessern ( n  = 29). Bei der weiteren Bewertung der IKT konnten diese in verschiedene funktionale Unterkategorien eingeteilt werden; anhand dieser Kategorien lässt sich das disruptive Potenzial neuer IKT abschätzen. Schlussfolgerung IKT gewinnen in der Rheumatologie zunehmend an Bedeutung und können das Leben der Patienten und die ärztliche Berufsausübung beeinflussen. Sowohl die Eigenschaften als auch das disruptive Potenzial der in den Artikeln genannten Technologien sind sehr unterschiedlich. Bei der Untersuchung der IKT haben sich Ärzte bisher auf neue diagnostische und therapeutische Verfahren konzentriert, aber selten auf ihr disruptives Potenzial. Die Autoren empfehlen, mehr Anstrengungen zu unternehmen, um zu untersuchen, ob IKT die Art und Weise, wie Rheumatologie durchgeführt wird, verändern und wer die Kontrolle darüber hat. Insbesondere Technologien, die potenziell Ärzte durch Maschinen ersetzen, die Kontrolle über die Definition von Qualität in der Medizin übernehmen und/oder proprietäres Wissen schaffen, das Ärzten nicht zugänglich ist, bedürfen weiterer Forschung.
    Type of Medium: Online Resource
    ISSN: 0340-1855 , 1435-1250
    URL: Article
    DOI: 10.1007/s00393-022-01222-4
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 1463308-5
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Online Resource
    Open Access Request
    Availability (electronic / print)
  • 2
    Online Resource
    Online Resource
    Differential diagnosis of high serum creatine kinase levels in systemic lupus erythematosus
    Springer Science and Business Media LLC ; 2003
    In:  Rheumatology International Vol. 23, No. 6 ( 2003-11-1), p. 319-323
    Details
    In: Rheumatology International, Springer Science and Business Media LLC, Vol. 23, No. 6 ( 2003-11-1), p. 319-323
    Type of Medium: Online Resource
    ISSN: 0172-8172 , 1437-160X
    URL: Article
    DOI: 10.1007/s00296-003-0309-0
    RVK:
    XA 10000
    Language: Unknown
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2003
    detail.hit.zdb_id: 1464208-6
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Online Resource
    Open Access Request
    Availability (electronic / print)
  • 3
    Online Resource
    Online Resource
    The PICASO cloud platform for improved holistic care in rheumatoid arthritis treatment—experiences of patients and clinicians
    Springer Science and Business Media LLC ; 2021
    In:  Arthritis Research & Therapy Vol. 23, No. 1 ( 2021-12)
    Details
    In: Arthritis Research & Therapy, Springer Science and Business Media LLC, Vol. 23, No. 1 ( 2021-12)
    Abstract: Multimorbidity raises the number of essential information needed for delivery of high-quality care in patients with chronic diseases like rheumatoid arthritis (RA). We evaluated an innovative ICT platform for integrated care which orchestrates data from various health care providers to optimize care management processes. Methods The Horizon2020-funded research project PICASO (picaso-project.eu) established an ICT platform that offers integration of care services across providers and supports patients’ management along the continuum of care, leaving the data with the owner. Strict conformity with ethical and legal legislations was augmented with a usability-driven engineering process, user requirements gathering from relevant stakeholders, and expert walkthroughs guided developments. Developments based on the HL7/FHIR standard granting interoperability. Platform’s applicability in clinical routine was an essential aim. Thus, we evaluated the platform according to an evaluation framework in an observational 6-month proof-of-concept study with RA patients affected by cardiovascular comorbidities using questionnaires, interviews, and platform data. Results Thirty RA patients (80% female) participated, mean age 59 years, disease duration 13 years, average number of comorbidities 2.9. Home monitoring data demonstrated high platform adherence. Evaluations yielded predominantly positive feedback: The innovative dashboard-like design offering time-efficient data visualization, comprehension, and personalization was well accepted, i.e., patients rated the platform “overall” as 2.3 (1.1) (mean (SD), Likert scales 1–6) and clinicians recommended further platform use for 93% of their patients. They managed 86% of patients’ visits using the clinician dashboard. Dashboards were valued for a broader view of health status and patient-physician interactions. Platform use contributed to improved disease and comorbidity management (i.e., in 70% physicians reported usefulness to assess patients’ diseases and in 33% potential influence on treatment decisions; risk manager was used in 59%) and empowered patients (i.e., 48% set themselves new health-related goals, 92% stated easier patient-physician communications). Conclusion Comprehensive aggregation of clinical data from distributed sources in a modern, GDPR-compliant cloud platform can improve physicians’ and patients’ knowledge of the disease status and comorbidities as well as patients’ management. It empowers patients to monitor and positively contribute to their disease management. Effects on patients’ outcome, behavior, and changes in the health care systems should be explored by implementing ICT-based platforms enriched by upcoming Artificial Intelligence features where possible. Trial registration DRKS—German Clinical Trials Register, DRKS00013637 , prospectively registered. 17 January 2018.
    Type of Medium: Online Resource
    ISSN: 1478-6362
    URL: Article
    DOI: 10.1186/s13075-021-02526-7
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
    detail.hit.zdb_id: 2041668-4
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Online Resource
    Open Access Request
    Availability (electronic / print)
  • 4
    Online Resource
    Online Resource
    Digitalisierung und Künstliche Intelligenz in der Rheumatologie
    Georg Thieme Verlag KG ; 2023
    In:  Aktuelle Rheumatologie Vol. 48, No. 04 ( 2023-08), p. 221-221
    Details
    In: Aktuelle Rheumatologie, Georg Thieme Verlag KG, Vol. 48, No. 04 ( 2023-08), p. 221-221
    Abstract: Wohl kaum ein anderer Bereich wird die Medizin in den nächsten Jahren derart revolutionieren wie die Anwendung digitaler Applikationen und künstlicher Intelligenz (KI). Die Geschwindigkeit und das Ausmaß der Veränderungen in der Medizin durch Apps und KI lassen sich heute noch gar nicht vollumfänglich erfassen. Die Erfahrungen mit Smartphones und sozialen Medien haben uns jedoch gezeigt, wie gewaltig die Auswirkung technischer Innovationen sein können.
    Type of Medium: Online Resource
    ISSN: 0341-051X , 1438-9940
    URL: Article
    DOI: 10.1055/a-2030-4648
    RVK:
    XA 10000
    Language: German
    Publisher: Georg Thieme Verlag KG
    Publication Date: 2023
    detail.hit.zdb_id: 2041294-0
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Online Resource
    Open Access Request
    Availability (electronic / print)
  • 5
    Online Resource
    Online Resource
    Trends in idiopathic inflammatory myopathies: cross-sectional data from the German National Database
    Springer Science and Business Media LLC ; 2020
    In:  Rheumatology International Vol. 40, No. 10 ( 2020-10), p. 1639-1647
    Details
    In: Rheumatology International, Springer Science and Business Media LLC, Vol. 40, No. 10 ( 2020-10), p. 1639-1647
    Abstract: To describe trends in outcomes among patients with idiopathic inflammatory myopathies (IIM) over two decades. Methods From 1997 to 2017, a total of 1079 IIM patients were documented in the National Database of the German Collaborative Arthritis Centers. Annual cross-sectional data on treatment, disease activity, patient-reported outcomes, hospitalization and employment were compared across the years. Information on phenotypes, organ manifestations and autoantibodies was collected for a subset to compare the assessment of global health, pain, fatigue and sleeping disorders. Results In 2017, significantly more IIM patients were assessed to be in low disease activity (94%) than in 1997 (59%), p   〈  0.01. Pain ( p  = 0.001), global health ( p  = 0.049), fatigue ( p  = 0.03) and sleeping disorders ( p  = 0.01) also improved since recording. Glucocorticoid use decreased from 84 to 58% ( p   〈  0.01). Employment in patients  〈  65 years remained unchanged (53%), while early retirement (23–9%), hospitalization/year (34–18%) and sick leave (52–24%) decreased. A total of 186 patients with information on subtypes were classified as polymyositis (44%), dermatomyositis (33%), anti-synthetase syndrome (10%), overlapping-myositis (8%), inclusion body myositis (2%), necrotizing myositis (0.5%) and unspecific (3%). The most frequently reported symptoms were limitations in global health (60%), fatigue (57%) and sleeping disorders (51%), and all of them were most frequent in overlap-myositis. Pulmonary hypertension and cardiomyopathy were associated with poor outcomes regarding global health, daily activities and fatigue. Conclusion IIM patients report better outcomes than 20 years ago, along with good physician-reported disease control. Global health, fatigue and sleeping disorders are relevant patient-reported domains in IIM.
    Type of Medium: Online Resource
    ISSN: 0172-8172 , 1437-160X
    URL: Article
    DOI: 10.1007/s00296-020-04634-0
    RVK:
    XA 10000
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2020
    detail.hit.zdb_id: 1464208-6
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Online Resource
    Open Access Request
    Availability (electronic / print)
  • 6
    Online Resource
    Online Resource
    Proof-of-Concept Double-Blind Placebo-Controlled Trial Measuring Cartilage Composition in Early Rheumatoid Arthritis under TNF-α-Inhibitor Therapy
    MDPI AG ; 2023
    In:  Journal of Clinical Medicine Vol. 12, No. 6 ( 2023-03-16), p. 2306-
    Details
    In: Journal of Clinical Medicine, MDPI AG, Vol. 12, No. 6 ( 2023-03-16), p. 2306-
    Abstract: Low levels of delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) values are indicative of cartilage degeneration. Patients with early rheumatoid arthritis are known to have low dGEMRIC values due to inflammatory activity. The additional effect of biological disease-modifying antirheumatic drug (bDMARD) and conventional synthetic disease-modifying antirheumatic drug (csDMARD) treatment on cartilage status is still unclear. In this prospective, double-blinded, randomized proof-of-concept clinical trial, patients with early rheumatoid arthritis (disease duration less than 12 months from symptoms onset) were treated with methotrexate + adalimumab (10 patients: 6/4 (f/m)). A control group with methotrexate alone (four patients: 2/2 (f/m)) was used. Cartilage integrity in the metacarpophalangeal joints was compared using dGEMRIC at baseline, 12, and 24 weeks after treatment initiation. A statistically significant increase in dGEMRIC levels was found in the adalimumab group considering the results after 12 and 24 weeks of therapy (p 〈 0.05) but not in the control group (p: non-significant). After 24 weeks, a tendency towards increased dGEMRIC values under combination therapy was observed, whereas methotrexate alone showed a slight decrease without meeting the criteria of significance (dGEMRIC mean change: +85.8 ms [−156.2–+346.5 ms] vs. 30.75 ms [−273.0–+131.0 ms] ; p: non-significant). After 24 weeks of treatment with a combination of methotrexate and adalimumab, a trend indicating improvement in cartilage composition is seen in patients with early rheumatoid arthritis. However, treatment with methotrexate alone showed no change in cartilage composition, as observed in dGEMRIC sequences of metacarpophalangeal joints.
    Type of Medium: Online Resource
    ISSN: 2077-0383
    URL: Article
    DOI: 10.3390/jcm12062306
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2662592-1
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Online Resource
    Open Access Request
    Availability (electronic / print)
  • 7
    Online Resource
    Online Resource
    Sustained agreement rates in the longitudinal assessment of lupus patients to a Broad Consent for personal data and specimen usage in the RHINEVIT biobank
    Frontiers Media SA ; 2023
    In:  Frontiers in Medicine Vol. 10 ( 2023-6-21)
    Details
    In: Frontiers in Medicine, Frontiers Media SA, Vol. 10 ( 2023-6-21)
    Abstract: Biobanks are essential structures for scientific research. The RHINEVIT biobank is used to recruit biomaterials from rheumatology patients in outpatient care and to conduct clinical research studies (e.g., cohort studies) and basic research. RHINEVIT established Broad Consents (BC) to allow extensive and relevant usage of data and biospecimens without the need for specific project restrictions. For quality assurance, we compared the consent rate of individual items of the BC versions in patients with systemic lupus erythematosus (SLE) in the longitudinal study. Methods BCs were used for biomaterial donation. Informed consent data from RHINEVIT were analyzed. Due to the content restructuring of the BC items due to changes from the templates of the working group of the Medical Ethics Commissions in the Federal Republic of Germany and GDPR requirements, content mapping of the items was performed for the analysis. Results From September 2015 to March 2022, 291 SLE outpatients donated biomaterials. In 119 patients, the BC was renewed at least once in a subsequent biomaterial donation. Three biomaterial donations were obtained from 21 patients and four from six patients using the respective BC. However, one consent was later revoked. Consent to the BC topics showed consistently high rates of agreement (range 97.5%−100%), with only some patients disagreeing with individual topics. This remained stable over time (median 526 days [Q1 400, Q3 844]). None of the patients disagreed with a certain topic in two consecutive visits. Conclusion Modifications to the BC did not result in any relevant changes in the approval rates for SLE patients. RHINEVIT's BC is successfully used for the quality-assured handling of excellently annotated biomaterial. The long-term use of these highly valuable biospecimens for unrestricted research, also in an international context, remains assured.
    Type of Medium: Online Resource
    ISSN: 2296-858X
    URL: Article
    DOI: 10.3389/fmed.2023.1208006
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2023
    detail.hit.zdb_id: 2775999-4
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Online Resource
    Open Access Request
    Availability (electronic / print)
  • 8
    Online Resource
    Online Resource
    One year of digital health applications (DiGA) in Germany – Rheumatologists’ perspectives
    Frontiers Media SA ; 2022
    In:  Frontiers in Medicine Vol. 9 ( 2022-10-25)
    Details
    In: Frontiers in Medicine, Frontiers Media SA, Vol. 9 ( 2022-10-25)
    Abstract: Based on given legislation the German approach to digital health applications (DiGA) allows reimbursed prescription of approved therapeutic software products since October 2020. For the first time, we evaluated DiGA-related acceptance, usage, and level of knowledge among members of the German Society for Rheumatology (DGRh) 1 year after its legal implementation. Materials and methods An anonymous cross-sectional online survey, initially designed by the health innovation hub (think tank and sparring partner of the German Federal Ministry of Health) and the German Pain Society was adapted to the field of rheumatology. The survey was promoted by DGRh newsletters and Twitter-posts. Ethical approval was obtained. Results In total, 75 valid response-sets. 80% reported to care ≥ 70% of their working time for patients with rheumatic diseases. Most were working in outpatient clinics/offices (54%) and older than 40 years (84%). Gender distribution was balanced (50%). 70% knew the possibility to prescribe DiGA. Most were informed of this for the first time via trade press (63%), and only 8% via the scientific/professional society. 46% expect information on DiGA from the scientific societies/medical chambers (35%) but rarely from the manufacturer (10%) and the responsible ministry (4%). Respondents would like to be informed about DiGA via continuing education events (face-to-face 76%, online 84%), trade press (86%), and manufacturers′ test-accounts (64%). Only 7% have already prescribed a DiGA, 46% planned to do so, and 47% did not intend DiGA prescriptions. Relevant aspects for prescription are provided. 86% believe that using DiGA/medical apps would at least partially be feasible and understandable to their patients. 83% thought that data collected by the patients using DiGA or other digital solutions could at least partially influence health care positively. 51% appreciated to get DiGA data directly into their patient documentation system/electronic health record (EHR) and 29% into patient-owned EHR. Conclusion Digital health applications awareness was high whereas prescription rate was low. Mostly, physician-desired aspects for DiGA prescriptions were proven efficacy and efficiency for physicians and patients, risk of adverse effects and health care costs were less important. Evaluation of patients’ barriers and needs is warranted. Our results might contribute to the implementation and dissemination of DiGA.
    Type of Medium: Online Resource
    ISSN: 2296-858X
    URL: Article
    DOI: 10.3389/fmed.2022.1000668
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2775999-4
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Online Resource
    Open Access Request
    Availability (electronic / print)
  • 9
    Online Resource
    Online Resource
    Activity tracker in Rheumatology—‘new’ data for improved patient management in routine care?
    Oxford University Press (OUP) ; 2022
    In:  Rheumatology Vol. 61, No. 7 ( 2022-07-06), p. 2712-2713
    Details
    In: Rheumatology, Oxford University Press (OUP), Vol. 61, No. 7 ( 2022-07-06), p. 2712-2713
    Type of Medium: Online Resource
    ISSN: 1462-0324 , 1462-0332
    URL: Article
    DOI: 10.1093/rheumatology/keab919
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2022
    detail.hit.zdb_id: 1474143-X
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Online Resource
    Open Access Request
    Availability (electronic / print)
  • 10
    Online Resource
    Online Resource
    Functional vascular acrosyndromes
    Springer Science and Business Media LLC ; 2022
    In:  Die Innere Medizin
    Details
    In: Die Innere Medizin, Springer Science and Business Media LLC
    Type of Medium: Online Resource
    ISSN: 2731-7080 , 2731-7099
    URL: Article
    DOI: 10.1007/s00108-022-01340-w
    Language: German
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 3124793-3
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Online Resource
    Open Access Request
    Availability (electronic / print)
Nothing or not found what you are looking for? Please check your search query or use the Interlibrary Loan Search.
Close ⊗
This website uses cookies and the analysis tool Matomo. Further information can be found on the KOBV privacy pages