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  • 1
    Online Resource
    Online Resource
    ECO-Vector LLC ; 2016
    In:  Pediatrician (St. Petersburg) Vol. 7, No. 3 ( 2016-09-15), p. 128-135
    In: Pediatrician (St. Petersburg), ECO-Vector LLC, Vol. 7, No. 3 ( 2016-09-15), p. 128-135
    Abstract: Pneumonia is one of significant problems among infections of low airways in children. Morbidity of common-acquired pneumonia (CAP) continues to go in last year’s. Data available in the literature show, that pneumonia with empyema possibly associated with high risk of chronic obstructive pulmonary diseases, asthma and recurrent case of pneumonia in last life. Fatal pneumonia or developing chronic obstruction lung diseases occur mainly in children after severe and complicated forms of pneumonia, this information is presented in native and foreign literature. Currently pneumonia with the heavy and complicated current is a major cause of infant mortality or promotes development of a chronic obstruction lung diseases. Mortality from pneumonia is 3-19% according to different authors. The risk of respiratory diseases in the 3-6 months after pneumonia increased in children who underwent pneumonia. After complicated CAP the complete resolution of the inflammatory happens on 6-9 month. After not complicated САР forms at 10-30% of children radiological changes within 2-6 weeks were noted. In one research it is reported that the full recovery from slow resolving pneumonia at 96% of children has come on 6-8 month of the dispensary period. Some authors in the scientific works use immunomodulators and vaccinations to reduce the residual variation in the lungs and improve recovery time dramatically of pneumonia. In follow up study the important task is a identifying and elimination of risk factors for improvement of treatment and dispensary period for slow resolving pneumonia, recurrent case of pneumonia, sever pneumonia.
    Type of Medium: Online Resource
    ISSN: 2587-6252 , 2079-7850
    URL: Issue
    Language: Unknown
    Publisher: ECO-Vector LLC
    Publication Date: 2016
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  • 2
    Online Resource
    Online Resource
    ECO-Vector LLC ; 2019
    In:  HERALD of North-Western State Medical University named after I.I. Mechnikov Vol. 11, No. 2 ( 2019-08-09), p. 71-78
    In: HERALD of North-Western State Medical University named after I.I. Mechnikov, ECO-Vector LLC, Vol. 11, No. 2 ( 2019-08-09), p. 71-78
    Abstract: Background. Mycoplasma pneumoniae is included in the group of atypical pathogens of acute respiratory diseases. Mycoplasma pneumoniae is characterized by a tendency to prolonged course with progressive changes in the lungs. Main value in the confirmation of mycoplasma infection has microbiome in biosubstrates selection and serological diagnostics: the determination of specific immunoglobulins IgM or IgG in the dynamics to M. pneumoniae. Antibacterial therapy of mycoplasma pneumonia is prescribed based on the sensitivity of the pathogen to them. The duration of antibiotic treatment of mycoplasma pneumonia is determined by the dynamics of clinical and radiological data. Materials and methods. The article describes the features of the clinical course of mycoplasma pneumonia in a patient with tubinfection proceeding with bronchoadenitis and obstruction of the bronchus, which necessitated a differential diagnosis with tuberculosis of the intrathoracic lymph nodes and the appointment of repeated courses of antibiotic treatment.Results. In the described clinical case, the duration of Mycoplasma infection exceeded 3.5 months, during which time the patient received several courses of antibiotics. Mycoplasma pneumonia had a prolonged course, accompanied by bronchoadenitis.Conclusion. Our observations show the need to study the effectiveness of extended courses of antibiotics from the azalid group in the treatment of prolonged and complicated forms of Mycoplasma pneumonia.
    Type of Medium: Online Resource
    ISSN: 2618-9704 , 2618-7116
    Language: Unknown
    Publisher: ECO-Vector LLC
    Publication Date: 2019
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  • 3
    In: Pediatrics. Consilium Medicum, Consilium Medicum, , No. 1 ( 2022-05-10), p. 20-27
    Abstract: Aim. Assessment of the state of compensatory resources and the degree of adaptation of the body to environmental conditions in early and full-term infants in comparison with each other and with practically healthy children. Materials and methods. Under the supervision of 135 infants. 110 were born from mothers with a burdened somatic and obstetric-gynecological history, 41 of them were born at 3738 weeks (Group 1), 69 at 3942 weeks (Group 2). The control group (Group 3) consisted of 25 practically healthy children born to practically healthy mothers as a result of physiological pregnancies and childbirth at 3840 weeks. The children were examined in dynamics at the age of 1 (n=126), 3 (n=116), 6 (n=110), 12 (n=111) months. A comprehensive analysis of the data of anamnesis, physical examination, cardiointervalography was carried out. The following parameters were evaluated initially and in response to the tilt test: mode (М0), mode amplitude (AM0), delta x (∆Х), voltage index (IN). Nonparametric methods of statistical analysis were used. Results. At the age of 2 to 3 days infants born to women with a history of poor health recorded a significant decrease in the median IN1 value, respectively, in Groups 1, 2, and 3, which indicates a decrease in compensatory reserves, particularly in neonates born at 3840 weeks. At 1 month of age, Group 1 and 2 had higher median IN1 values of 804 and 746 versus 550 in Group 3, indicating the development of compensatory resource tension, particularly in children born at 3738 weeks. At 3 months of age, children in group 1 retained a compensatory tension of IN1 resources 521 versus 468 and 460 in groups 2 and 3. At 6 months of age, there is a slight decrease in compensatory IN1 reservers at 6 months of age in children from women with a history of a history of a history of a history of a disease 376 and 357 versus 400 in Group 3. At 12 months of age, children in the main groups have even more decreased compensatory resources, especially in group 1 IN1 206, 284 and 380 respectively in groups 1, 2 and 3. Conclusion. The decrease of functional reserve of adaptation in children of groups 1st and 2nd was facilitated by the influence burdened with somatic and obstetric-gynecological history of mothers, regardless of gestational age and subsequently the health characteristics of children themselves. The statistically significant differences found in the state of compensatory resources and the degree of adaptation of the organism to environmental conditions justify the personalized approach, which justifies a personalized approach when choosing rehabilitation measures.
    Type of Medium: Online Resource
    ISSN: 2658-6622 , 2658-6630
    Language: Unknown
    Publisher: Consilium Medicum
    Publication Date: 2022
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  • 4
    In: Medical academic journal, ECO-Vector LLC, Vol. 2, No. 2 ( 2022-11-06), p. 137-146
    Abstract: BACKGROUND: Cystic fibrosis is one of the most frequent monogenic diseases, in which, in addition to medical measures, measures for the prevention of the infectious process in the lungs are of great importance, which is provided by a clear organization of the work of any medical institution where patients are observed and where medical and rehabilitation measures are carried out. AIM: The article describes the experience of the childrens Center in St. Petersburg to prevent cross-infection of patients with cystic fibrosis who have the different luge microbiome. MATERIALS AND METHODS: The measures taken included a system for monitoring and dynamic control of the seeded pathogenic microflora with a strict separation of patients with cystic fibrosis, who had the isolation and carriage of various pathogens. The system provided for the separation of flows of patients with cystic fibrosis and the prevention of cross-infection, as well as a number of activities related to the disinfection of equipment. RESULTS: The methods adopted and put into practice have ensured the prevention of cross-infection of patients with cystic fibrosis, excreting various pathogenic bacteria from sputum. The patient management system made it possible to halve the number of hospitalizations of patients with Pseudomonas aeruginosa infection per CF patient per year: from 1.3 in 2001 to 0.6 in 2021, reduce the risk of cross-infection, reduce the number of relapses, hospitalizations and the average length of stay of a patient in a hospital. CONCLUSIONS: The developed system of assistance has shown its effectiveness and can be implemented in one form or another in the work of cystic fibrosis treatment centers in the Russian Federation.
    Type of Medium: Online Resource
    ISSN: 2687-1378 , 1608-4101
    URL: Issue
    Language: Unknown
    Publisher: ECO-Vector LLC
    Publication Date: 2022
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  • 5
    In: Pediatrics. Consilium Medicum, Consilium Medicum, , No. 3 ( 2021-09-15), p. 231-238
    Abstract: Aim. Assessment of electrocardiographic indicators in infants born on time with delayed intrauterine growth and mild development. Materials and methods. Under the supervision of 164 infants. From mothers with an aggravated somatic and obstetric-gynecological history, 139 children were born: 71 (gr. 1) with delayed intrauterine growth and development of mild severity, 68 (gr. 2) without delayed intrauterine growth and development. The control group (gr. 3) consisted of 25 practically healthy children born to practically healthy mothers. All children were born full-time. They were examined in dynamics at the age of 1 (n=154), 3 (n=142), 6 (n=133), 12 (n=130) months. A comprehensive analysis of the data of history, physical examination, electrocardiography was carried out. There was no medical intervention. The duration of the study is 3 years. Heart rate, incidence of early ventricular repolarization syndrome and nonspecific disorders of the repolarization process were evaluated; in the II standard retraction, morphology, amplitude in millimeters and width in seconds of the tooth P; duration in seconds of PQ interval (PR), QRS complex and QT interval; morphology, amplitude in millimeters of tooth T. Non-parametric methods of statistical analysis were used. Results. The median amplitude of the tooth P on day 23 in children of subgr. 1b, compared with children of gr. 3, is 0.2 mm less; 1 month in children of gp. 1 (1b), compared with children of gp. 3, less by 0.1 mm; at 3 months in children of subgp. 1a, compared with children of subgp. 1b, less by 0.35 mm, in children of subgp. 1b, compared with children of gp. 3, more by 0.2 mm; at 6 months in children of gp. 1 (1a and 1b), compared with children of gr. 3, more by 0.2 mm; at 12 months in children of subgp. 1a, compared with children of subgp. 1b, less by 0.2 mm, in children of subgp. 1b, compared with children of gr. 2, more by 0.2 mm, in children of gp. 1 (1a), compared with children of gr. 3, less by 0.2 (0.5) mm, and, compared with children of gr. 3, less by 0.2 mm. From 3 to 6 months increased in children of subgp. 1a by 0.35 mm. In children of gp. 1st (1a), a slowdown from 23 days to 1 month of intradermal conduction by 0.01 s, from 1 to 3 months of intraventricular conduction by 0.01 s, from 3 to 6 months of intradermal conduction by 0.01 s. Electrical systole in children of gr. 1 slowed from 1 to 3 and from 3 to 6 months by 0.01 s; in children of subgp. 1a from 1 to 3 months increased by 0.01 s, from 3 to 6 months decreased by 0.01 s, from 6 to 12 months increased by 0.01 s. Median tooth amplitude T on 23 days, 1 month in children of gp. 1 (1a and 1b), compared to children of gr. 3, more by 0.4 mm and 0.3 mm, respectively; at 3 months in children of subgp. 1a, compared with children of subgp. 1b, less by 0.35 mm, and, compared with children of gr. 2, less by 0.2 mm, in children of subgp. 1b, compared with children of gr. 2 more by 0.15 mm, in children of gp. 1 (1b), compared with children of gr. 3, more by 0.3 (0.45) mm; at 12 months in children of subgp. 1b, compared with children of gr. 2, more by 0.4 mm, in children of gp. 1 (1a), compared with children of gp. 3, less by 0.3 mm. From 23 days to 1 month in children of gp. 1 (1a) increased by 0.8 mm. Conclusion. Certain peculiarities of electrocardiogram in dynamics of growth and development of the organism of infants born on time with delay of intrauterine growth and development of mild severity related to volume overload of atrium, enlargement of interventricular septum, hypoxia, sympathetic activity, requiring corrective events are revealed.
    Type of Medium: Online Resource
    ISSN: 2658-6622 , 2658-6630
    Language: Unknown
    Publisher: Consilium Medicum
    Publication Date: 2021
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