In:
Animal Bioscience, Asian Australasian Association of Animal Production Societies, Vol. 36, No. 3 ( 2023-03-01), p. 385-403
Abstract:
Male fertility is affected by multiple endogenous stressors, including reactive oxygen species (ROS), which greatly deteriorate the fertility. However, physiological levels of ROS are required by sperm for the proper accomplishment of different cellular functions including proliferation, maturation, capacitation, acrosomal reaction, and fertilization. Excessive ROS production creates an imbalance between ROS production and neutralization resulting in oxidative stress (OS). OS causes male infertility by impairing sperm functions including reduced motility, deoxyribonucleic acid damage, morphological defects, and enhanced apoptosis. Several in-vivo and in-vitro studies have reported improvement in quality-related parameters of sperm following the use of different natural and synthetic antioxidants. In this review, we focus on the causes of OS, ROS production sources, mechanisms responsible for sperm damage, and the role of antioxidants in preserving sperm fertility.
Type of Medium:
Online Resource
ISSN:
2765-0189
,
2765-0235
Language:
English
Publisher:
Asian Australasian Association of Animal Production Societies
Publication Date:
2023
detail.hit.zdb_id:
3055169-9
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