In:
International Journal of PIXE, World Scientific Pub Co Pte Ltd, Vol. 07, No. 01n02 ( 1997-01), p. 45-48
Abstract:
PIXE, Particle Induced X-ray Emission, is a Powerful, multi-elemental analysis method which has many distinguishing features and has been used in varies research fields. Recently the method of applying baby cyclotrons for nuclear medicine to PIXE has been developed. This enables us to study biomedical phenomena from the physical point of view. Mouse bone marrow stromal cells were transferred bacterial β -galactosidase gene (LacZ gene) by murine retroviral vectors. Analysis of the bone marrow stromal cells with the LacZ gene by PIXE revealed remarkable changes of intracellular trace elements compared with the normal control cells. These results indicate that gene transfer by retroviral vectors may bring about a dynamic change of intracellular circumstances of the target cell.
Type of Medium:
Online Resource
ISSN:
0129-0835
,
1793-6616
DOI:
10.1142/S0129083597000060
Language:
English
Publisher:
World Scientific Pub Co Pte Ltd
Publication Date:
1997
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