In:
Journal of Virology, American Society for Microbiology, Vol. 3, No. 3 ( 1969-03), p. 326-330
Abstract:
Mixed infection of monkey kidney cells with two mutants of the LSc2ab strain of poliovirus, one resistant to guanidine and the other resistant to both dextran sulfate and 2-(α-hydroxybenzyl)-benzimidazole (HBB), yielded progeny in which the number of gua r dex r particles exceeded by a factor of 7 to 10 the expected number of similar particles occurring through spontaneous mutation; recombination would explain the fairly high excess of doubly mutant particles that was obtained. Scoring of HBB resistance in 50 gua r dex r clones suggested that, during recombination, resistance to dextran sulfate is not associated with HBB resistance.
Type of Medium:
Online Resource
ISSN:
0022-538X
,
1098-5514
DOI:
10.1128/jvi.3.3.326-330.1969
Language:
English
Publisher:
American Society for Microbiology
Publication Date:
1969
detail.hit.zdb_id:
1495529-5
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