In:
Journal of Arrhythmia, Wiley, Vol. 31, No. 2 ( 2015-04), p. 94-100
Abstract:
The need for ways to minimize the number of implantable cardioverter‐defibrillator (ICD) shocks is increasing owing to the risk of its adverse effects on life expectancy. Studies have shown that a longer detection time for ventricular tachyarrhythmia reduces the safety of therapies, in terms of syncope and mortality, but not substantially in terms of the success rate. We aimed to evaluate the effects of increased number of intervals to detect (NID) VF on the safety of ICD shock therapy and on the reduction of inappropriate shocks. Methods The present study was a prospective, multicenter, randomized, crossover study. Randomized VF induction testing with NID 18/24 or 30/40 was performed to compare the success rate of defibrillation with a 25‐J shock and the time to detection. Inappropriate shock episodes were simulated retrospectively to evaluate a possibility of episodes avoidable at NID 24/32 and 30/40. Results Thirty‐one consecutive patients implanted with an ICD or cardiac resynchronization therapy‐defibrillator (CRT‐D) were enrolled in this study. The success rate of defibrillation was 100% in both NID groups at the first shock. The time from VF induction to detection showed a significant increase in the NID 30/40 group (6.16±1.29 s vs. 9.00±1.31 s, p 〈 0.001). Among the 120 patients implanted with an ICD or CRT‐D, 10 experienced 32 inappropriate shock episodes. The inappropriate shock reduction rate was 53.1% and 62.5% with NID 24/32 and 30/40, respectively. Conclusions The findings of this SANKS study suggest that VF NID 30/40 does not compromise the safety of ICD shock therapy, while decreasing the number of inappropriate shocks.
Type of Medium:
Online Resource
ISSN:
1880-4276
,
1883-2148
DOI:
10.1016/j.joa.2014.08.003
Language:
English
Publisher:
Wiley
Publication Date:
2015
detail.hit.zdb_id:
2696593-8
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