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Congenital absence of portal vein with multiple hyperplastic nodular lesions in the liver

Tanaka, Yasuo ; Takayanagi, Masaki ; Shiratori, Yasushi ; [et al.]

Springer Science and Business Media LLC ; 2003

In: Journal of Gastroenterology Vol. 38, No. 3 ( 2003-3-1), p. 288-294

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In: Journal of Gastroenterology, Springer Science and Business Media LLC, Vol. 38, No. 3 ( 2003-3-1), p. 288-294

Type of Medium: Online Resource

ISSN: 0944-1174 , 1435-5922

URL: Article

DOI: 10.1007/s005350300050

Language: Unknown

Publisher: Springer Science and Business Media LLC

Publication Date: 2003

detail.hit.zdb_id: 1473159-9

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Analysis of Patient Outcome after Non-curative Resection for Hepatocellular Carcinoma Using Nationwide Survey Data in Japan

Aoki, Taku ; Kubota, Keiichi ; Kubo, Shoji ; [et al.]

Springer Science and Business Media LLC ; 2021

In: World Journal of Surgery Vol. 45, No. 2 ( 2021-02), p. 607-614

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In: World Journal of Surgery, Springer Science and Business Media LLC, Vol. 45, No. 2 ( 2021-02), p. 607-614

Type of Medium: Online Resource

ISSN: 0364-2313 , 1432-2323

URL: Article

DOI: 10.1007/s00268-020-05830-6

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2021

detail.hit.zdb_id: 1463296-2

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Pseudomyxoma peritonei due to adenocarcinoma of the lung: Case report

Kurita, Masahiro ; Komatsu, Hiroshi ; Hata, Yasuo ; [et al.]

Springer Science and Business Media LLC ; 1994

In: Journal of Gastroenterology Vol. 29, No. 3 ( 1994-06), p. 344-348

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In: Journal of Gastroenterology, Springer Science and Business Media LLC, Vol. 29, No. 3 ( 1994-06), p. 344-348

Type of Medium: Online Resource

ISSN: 0944-1174 , 1435-5922

URL: Article

DOI: 10.1007/BF02358375

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 1994

detail.hit.zdb_id: 1473159-9

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Value of post-vascular phase (Kupffer imaging) by contrast-enhanced ultrasonography using Sonazoid in the detection of hepatocellular carcinoma

Goto, Eriko ; Masuzaki, Ryota ; Tateishi, Ryosuke ; [et al.]

Springer Science and Business Media LLC ; 2012

In: Journal of Gastroenterology Vol. 47, No. 4 ( 2012-4), p. 477-485

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In: Journal of Gastroenterology, Springer Science and Business Media LLC, Vol. 47, No. 4 ( 2012-4), p. 477-485

Type of Medium: Online Resource

ISSN: 0944-1174 , 1435-5922

URL: Article

DOI: 10.1007/s00535-011-0512-9

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2012

detail.hit.zdb_id: 1473159-9

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Impact of PNPLA3 polymorphisms on the development of hepatocellular carcinoma in patients with chronic hepatitis C virus infection

Sato, Masaya ; Kato, Naoya ; Tateishi, Ryosuke ; [et al.]

Wiley ; 2014

In: Hepatology Research Vol. 44, No. 10 ( 2014-10)

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In: Hepatology Research, Wiley, Vol. 44, No. 10 ( 2014-10)

Abstract: The PNPLA3 rs738409 C 〉 G polymorphism (encoding for I148M ) has recently been identified as a susceptibility factor for steatosis‐mediated liver damage. We evaluated the influence of this polymorphism on hepatocarcinogenesis in patients with chronic hepatitis C ( CHC ) virus infection. Methods We genotyped the rs738409 single nucleotide polymorphism in 358 hepatitis C ‐associated hepatocellular carcinoma ( HCC ) patients and correlated the age at onset of HCC and the interval between hepatitis C virus ( HCV ) infection and the development of HCC in patients with each genotype. Results The frequencies of CC , CG and GG genotypes were 27.9% (100/358), 49.2% (176/358) and 22.9% (82/358), respectively, and were in H ardy– W einberg equilibrium. The median age at onset of HCC for the GG genotype was significantly younger compared to for non‐ GG genotypes (67.81 vs 69.87 years, P 〈 0.001), and the median interval between HCV infection and the development of HCC was significantly shorter in patients with the GG genotype (39.96 vs 40.85 years, P = 0.008). PNPLA3 GG genotype was also associated with a higher aspartate aminotransferase level (69.5 vs 59.0 IU /L, P = 0.02), lower prothrombin time (73.0% vs 78.0%, P = 0.008) and a higher prevalence of histological steatosis (40.0% vs. 22.2%, P = 0.01) at the time of HCC onset. Conclusion The PNPLA3 genotype GG may be associated with accelerated hepatocarcinogenesis in CHC patients through increased steatosis in the liver.

Type of Medium: Online Resource

ISSN: 1386-6346 , 1872-034X

URL: Issue

URL: Article

DOI: 10.1111/hepr.2014.44.issue-10

DOI: 10.1111/hepr.12258

Language: English

Publisher: Wiley

Publication Date: 2014

detail.hit.zdb_id: 2006439-1

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Impact of hepatitis C virus on survival in patients undergoing resection of intrahepatic cholangiocarcinoma: Report of a Japanese nationwide survey

Kaibori, Masaki ; Yoshii, Kengo ; Kashiwabara, Kosuke ; [et al.]

Wiley ; 2021

In: Hepatology Research Vol. 51, No. 8 ( 2021-08), p. 890-901

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In: Hepatology Research, Wiley, Vol. 51, No. 8 ( 2021-08), p. 890-901

Abstract: We reviewed the data of a nationwide follow‐up survey to determine the impact of hepatitis C virus (HCV) infection on the outcomes of hepatectomy for mass‐forming (MF) type, and combined mass‐forming and periductal infiltrating (MF + PI) type intrahepatic cholangiocarcinoma (ICC). Methods In total, 956 patients with ICC who underwent curative hepatic resection were included in this cohort study, and patients were classified according to virus status. Patients were classified according to virus status as follows: HCV‐related ICC ( n = 138, 14.4%), hepatitis B virus (HBV)‐related ICC ( n = 43, 4.5%) and non‐virus‐related ICC ( n = 775, 81.1%). To control for variables, we used 1:1 propensity score‐matching to compare outcomes after surgery between HCV‐related ( n = 102) and non‐virus‐related ICC cases ( n = 102). Results We successfully matched HCV‐related and non‐virus‐related ICC cases with similar liver function and tumor characteristics. Patients with HCV‐related ICC had significantly shorter recurrence‐free survival (hazard ratio 0.62, 95% confidence interval 0.42–0.92, p = 0.016) and overall survival (hazard ratio: 0.57, 95% confidence interval: 0.37–0.88, p = 0.011) than patients with non‐virus‐related ICC. Cox proportional hazard analysis showed that HCV‐related ICC offered a worse prognosis than non‐virus‐related ICC. Conclusions HCV infection increases the risk of recurrence and worsens overall survival in patients after curative resection for MF and combined MF + PI type ICC.

Type of Medium: Online Resource

ISSN: 1386-6346 , 1872-034X

URL: Issue

URL: Article

DOI: 10.1111/hepr.v51.8

DOI: 10.1111/hepr.13676

Language: English

Publisher: Wiley

Publication Date: 2021

detail.hit.zdb_id: 2006439-1

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Steroid administration for ischemic complications after radiofrequency ablation: A retrospective study

Wake, Taijiro ; Tateishi, Ryosuke ; Moriyama, Makoto ; [et al.]

Wiley ; 2023

In: Hepatology Research Vol. 53, No. 7 ( 2023-07), p. 675-680

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In: Hepatology Research, Wiley, Vol. 53, No. 7 ( 2023-07), p. 675-680

Abstract: The aim of this study was to evaluate the effects of steroids on ischemic complications after radiofrequency ablation. Methods A total of 58 patients with ischemic complications were divided into two groups according to corticosteroid use or non‐use. Results A total of 13 patients who were administered steroids had a shorter duration of fever than those who were not administered steroids (median 6.0 vs. 2.0 days; p 〈 0.001). Linear regression analysis showed that steroid administration was associated with a reduction of 3.9 days in the duration of fever ( p = 0.008). Conclusions Steroid administration for ischemic complications after radiofrequency ablation may reduce the risk of fatal outcomes by blocking systemic inflammatory reactions.

Type of Medium: Online Resource

ISSN: 1386-6346 , 1872-034X

URL: Issue

URL: Article

DOI: 10.1111/hepr.v53.7

DOI: 10.1111/hepr.13891

Language: English

Publisher: Wiley

Publication Date: 2023

detail.hit.zdb_id: 2006439-1

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Evaluation of transcatheter arterial embolization prior to percutaneous tumor ablation in patients with hepatocellular carcinoma: a randomized controlled trial

Akamatsu, Masatoshi ; Yoshida, Haruhiko ; Obi, Shuntaro ; [et al.]

Wiley ; 2004

In: Liver International Vol. 24, No. 6 ( 2004-12), p. 625-629

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In: Liver International, Wiley, Vol. 24, No. 6 ( 2004-12), p. 625-629

Type of Medium: Online Resource

ISSN: 1478-3223 , 1600-0676

URL: Issue

URL: Article

DOI: 10.1111/liv.2004.24.issue-6

DOI: 10.1111/j.1478-3231.2004.0963.x

Language: English

Publisher: Wiley

Publication Date: 2004

detail.hit.zdb_id: 2025791-0

detail.hit.zdb_id: 2124684-1

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Gadoxetic Acid–Enhanced MR Imaging Predicts Simeprevir‐Induced Hyperbilirubinemia During Hepatitis C Virus Treatment: A Pilot Study

Okubo, Hironao ; Kitamura, Tsuneo ; Ando, Hitoshi ; [et al.]

Wiley ; 2017

In: The Journal of Clinical Pharmacology Vol. 57, No. 3 ( 2017-03), p. 369-375

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In: The Journal of Clinical Pharmacology, Wiley, Vol. 57, No. 3 ( 2017-03), p. 369-375

Abstract: Simeprevir is a substrate for organic anion‐transporting polypeptides (OATPs) that transport bilirubin. Hyperbilirubinemia is an adverse event reported during treatment of chronic hepatitis C patients with simeprevir plus pegylated interferon and ribavirin. Because gadoxetic acid is also a substrate of OATPs, pretreatment gadoxetic acid–enhanced magnetic resonance imaging (MRI) may predict hyperbilirubinemia during treatment. This prospective study therefore evaluated 11 consecutive patients with chronic hepatitis C who underwent gadoxetic acid–enhanced MRI prior to treatment with simeprevir plus pegylated interferon and ribavirin for 12 weeks, followed by pegylated interferon and ribavirin for an additional 12 weeks. Their contrast enhancement index (CEI), an index of liver parenchymal enhancement during the hepatobiliary phase, was assessed before treatment. Plasma trough concentrations (C trough ) of simeprevir were determined 7 days after its administration, and serum bilirubin concentrations were measured throughout the course of treatment. Six patients (55%) developed hyperbilirubinemia (≥1.6 mg/dL) during treatment. C trough was significantly higher in patients with than without hyperbilirubinemia ( P = .009), with a strong inverse relationship between CEI and C trough ( r = ‐0.911, P 〈 .001). CEI was significantly lower in patients with than without hyperbilirubinemia ( P = .009), but there were no significant differences between the 2 groups in pretreatment serum albumin concentrations and FIB‐4 index, an index of liver fibrosis. Hepatic enhancement with gadoxetic acid was related to C trough of simeprevir. Gadoxetic acid‐enhanced magnetic resonance imaging may predict the development of hyperbilirubinemia during treatment of hepatitis C patients with simeprevir plus pegylated interferon and ribavirin.

Type of Medium: Online Resource

ISSN: 0091-2700 , 1552-4604

URL: Issue

URL: Article

DOI: 10.1002/jcph.v57.3

DOI: 10.1002/jcph.811

RVK:

XA 52835

Language: English

Publisher: Wiley

Publication Date: 2017

detail.hit.zdb_id: 2010253-7

SSG: 15,3

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Power Doppler sonography for hepatocellular carcinoma: factors affecting the power Doppler signals of the tumors

Imamura, Masatoshi ; Shiratori, Yasushi ; Shiina, Shuichiro ; [et al.]

Wiley ; 2008

In: Liver Vol. 18, No. 6 ( 2008-12-12), p. 427-433

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In: Liver, Wiley, Vol. 18, No. 6 ( 2008-12-12), p. 427-433

Type of Medium: Online Resource

ISSN: 0106-9543

URL: Article

DOI: 10.1111/j.1600-0676.1998.tb00828.x

Language: English

Publisher: Wiley

Publication Date: 2008

detail.hit.zdb_id: 2124684-1

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