In:
Acta Crystallographica Section C Structural Chemistry, International Union of Crystallography (IUCr), Vol. 74, No. 12 ( 2018-12-01), p. 1759-1767
Abstract:
6-Hydroxy- N -(4-methoxyphenyl)-4-oxo-2,4-dihydro-1 H -pyrrolo[3,2,1- ij ]quinoline-5-carboxamide, C 19 H 16 N 2 O 4 , possesses strong diuretic properties and can be used as a new hypertension remedy. Two polymorphic modifications of this compound have been found, namely the triclinic polymorph (space group P \overline{1}), with one molecule in the asymmetric unit, and the monoclinic polymorph (space group P 2 1 / n ), with two molecules in asymmetric unit. An analysis of the pairwise interaction energies between the molecules in the crystal phase revealed differences in the crystal packing. The triclinic form has only one level of organization, namely a chain/column, while the monoclinic form has two levels of organization, with a chain/column as the primary basic structural motif and a layer as the secondary basic structural motif.
Type of Medium:
Online Resource
ISSN:
2053-2296
DOI:
10.1107/S2053229618016352
DOI:
10.1107/S2053229618016352/jx3022sup1.cif
DOI:
10.1107/S2053229618016352/jx30221msup2.hkl
DOI:
10.1107/S2053229618016352/jx30221tsup3.hkl
Language:
Unknown
Publisher:
International Union of Crystallography (IUCr)
Publication Date:
2018
detail.hit.zdb_id:
2025703-X
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