In:
European Journal of Organic Chemistry, Wiley, Vol. 2009, No. 34 ( 2009-12), p. 5998-6008
Abstract:
Cyclopropylamines are versatile intermediates and products both in organic synthesis in general and for active substances in particular. Although the synthesis of the corresponding enantiomerically pure cyclopropylboronic esters had been established previously, the C–B to C–N transformation was elusive. A detailed study directed towards the synthesis of several enantiomerically pure cyclopropylamines is disclosed; tranylcypromine [(1 S ,2 R )‐ 36 ] and the known belactosin A intermediate 43 were both obtained by use of trifluoroborates as key intermediates. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
Type of Medium:
Online Resource
ISSN:
1434-193X
,
1099-0690
DOI:
10.1002/ejoc.v2009:34
DOI:
10.1002/ejoc.200900882
Language:
English
Publisher:
Wiley
Publication Date:
2009
detail.hit.zdb_id:
1475010-7
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