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Turks fighting back against anti-evolution forces

Somel, Mehmet ; Somel, Rahsan Nazli Ozturkler ; Kence, Aykut

Springer Science and Business Media LLC ; 2007

In: Nature Vol. 445, No. 7124 ( 2007-1), p. 147-147

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In: Nature, Springer Science and Business Media LLC, Vol. 445, No. 7124 ( 2007-1), p. 147-147

Type of Medium: Online Resource

ISSN: 0028-0836 , 1476-4687

URL: Article

DOI: 10.1038/445147c

RVK:

TA 1000

RVK:

UA 1000

RVK:

WA 15000

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2007

detail.hit.zdb_id: 120714-3

detail.hit.zdb_id: 1413423-8

SSG: 11

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Bringing the understanding of evolution to Turkish public: A volunteer organization model for developing countries

Ozpolat, B. Duygu ; Akçay, Erol ; Somel, Nazli ; [et al.]

Elsevier BV ; 2010

In: Developmental Biology Vol. 344, No. 1 ( 2010-08), p. 439-

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In: Developmental Biology, Elsevier BV, Vol. 344, No. 1 ( 2010-08), p. 439-

Type of Medium: Online Resource

ISSN: 0012-1606

URL: Article

DOI: 10.1016/j.ydbio.2010.05.112

Language: English

Publisher: Elsevier BV

Publication Date: 2010

detail.hit.zdb_id: 1463203-2

SSG: 12

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Single hybrid population but multiple parental individuals at the origin of parthenogenetic rock lizards Darevskia sapphirina and D. bendimahiensis Schmidtler, & Eiselt Darevsky (1994) endemic to the area of Lake Van in East Turkey

Erdolu, Meriç ; Şahin, Mehmet Kürşat ; Somel, Mehmet ; [et al.]

Elsevier BV ; 2023

In: Molecular Phylogenetics and Evolution Vol. 189 ( 2023-12), p. 107925-

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In: Molecular Phylogenetics and Evolution, Elsevier BV, Vol. 189 ( 2023-12), p. 107925-

Type of Medium: Online Resource

ISSN: 1055-7903

URL: Article

DOI: 10.1016/j.ympev.2023.107925

Language: English

Publisher: Elsevier BV

Publication Date: 2023

detail.hit.zdb_id: 1471402-4

SSG: 12

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Variable kinship patterns in Neolithic Anatolia revealed by ancient genomes

Yaka, Reyhan ; Mapelli, Igor ; Kaptan, Damla ; [et al.]

Elsevier BV ; 2021

In: Current Biology Vol. 31, No. 11 ( 2021-06), p. 2455-2468.e18

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In: Current Biology, Elsevier BV, Vol. 31, No. 11 ( 2021-06), p. 2455-2468.e18

Type of Medium: Online Resource

ISSN: 0960-9822

URL: Article

DOI: 10.1016/j.cub.2021.03.050

Language: English

Publisher: Elsevier BV

Publication Date: 2021

detail.hit.zdb_id: 2019214-9

SSG: 12

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Effects of coumaphos on locomotor activities of different honeybee (Apis mellifera L.) subspecies and ecotypes

Arslan, Okan Can ; Erdem, Babür ; Somel, Mehmet ; [et al.]

Springer Science and Business Media LLC ; 2023

In: Apidologie Vol. 54, No. 4 ( 2023-08)

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In: Apidologie, Springer Science and Business Media LLC, Vol. 54, No. 4 ( 2023-08)

Abstract: The effects of acute sublethal doses of coumaphos, an acaricide used against Varroa destructor infestation in beekeeping, on the locomotor activities of four native honeybee subspecies of Türkiye including two ecotypes (Carniolan honeybee - A. m. carnica , Syrian honeybee - A. m. syriaca , Caucasian honeybee- A. m. caucasica , and Muğla and Yığılca ecotypes of Anatolian honeybee A. m. anatoliaca ) were investigated using an individual locomotor activity monitoring system. Analysis of locomotor activity data in the first 12-h, last 12-h, and 24-h time periods showed that bees from caucasica and carnica subspecies were not affected by coumaphos at all three acute doses (1, 2, and 5 μg coumaphos in 10 μl sucrose syrup for each bee). In contrast, bees from A. m. syriaca subspecies showed significantly elevated locomotor activity levels at 2 and 5 μg coumaphos doses within the first 12 h. Bees from both Muğla and Yığılca ecotypes of anatoliaca subspecies also showed elevated locomotor activity levels at 5 μg coumaphos dose but the magnitude of increase was lower in these ecotypes compared to that seen in syriaca subspecies in the first 12-h period. In general, increasing doses of coumaphos resulted in increased locomotor activity (locomotor activity), with differences in sensitivity across honeybee populations. Possible mechanisms underlying this variance and suggestions for further studies are discussed.

Type of Medium: Online Resource

ISSN: 0044-8435 , 1297-9678

URL: Article

DOI: 10.1007/s13592-023-01017-9

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2023

detail.hit.zdb_id: 2005148-7

SSG: 12

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Molecular footprint of Medawar’s mutation accumulation process in mammalian aging

Turan, Zeliha Gözde ; Parvizi, Poorya ; Dönertaş, Handan Melike ; [et al.]

Wiley ; 2019

In: Aging Cell Vol. 18, No. 4 ( 2019-08)

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In: Aging Cell, Wiley, Vol. 18, No. 4 ( 2019-08)

Abstract: Medawar's mutation accumulation hypothesis explains aging by the declining force of natural selection with age: Slightly deleterious germline mutations expressed in old age can drift to fixation and thereby lead to aging‐related phenotypes. Although widely cited, empirical evidence for this hypothesis has remained limited. Here, we test one of its predictions that genes relatively highly expressed in old adults should be under weaker purifying selection than genes relatively highly expressed in young adults. Combining 66 transcriptome datasets (including 16 tissues from five mammalian species) with sequence conservation estimates across mammals, here we report that the overall conservation level of expressed genes is lower at old age compared to young adulthood. This age‐related decrease in transcriptome conservation (ADICT) is systematically observed in diverse mammalian tissues, including the brain, liver, lung, and artery, but not in others, most notably in the muscle and heart. Where observed, ADICT is driven partly by poorly conserved genes being up‐regulated during aging. In general, the more often a gene is found up‐regulated with age among tissues and species, the lower its evolutionary conservation. Poorly conserved and up‐regulated genes have overlapping functional properties that include responses to age‐associated tissue damage, such as apoptosis and inflammation. Meanwhile, these genes do not appear to be under positive selection. Hence, genes contributing to old age phenotypes are found to harbor an excess of slightly deleterious alleles, at least in certain tissues. This supports the notion that genetic drift shapes aging in multicellular organisms, consistent with Medawar's mutation accumulation hypothesis.

Type of Medium: Online Resource

ISSN: 1474-9718 , 1474-9726

URL: Issue

URL: Article

DOI: 10.1111/acel.2019.18.issue-4

DOI: 10.1111/acel.12965

Language: English

Publisher: Wiley

Publication Date: 2019

detail.hit.zdb_id: 2099130-7

SSG: 12

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MTaxi: A comparative tool for taxon identification of ultra low coverage ancient genomes

Atağ, Gözde ; Vural, Kıvılcım Başak ; Kaptan, Damla ; [et al.]

F1000 Research Ltd ; 2023

In: Open Research Europe Vol. 2 ( 2023-7-7), p. 100-

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In: Open Research Europe, F1000 Research Ltd, Vol. 2 ( 2023-7-7), p. 100-

Type of Medium: Online Resource

ISSN: 2732-5121

URL: Journal

URL: Article

DOI: 10.12688/openreseurope

DOI: 10.12688/openreseurope.14936.2

Language: English

Publisher: F1000 Research Ltd

Publication Date: 2023

detail.hit.zdb_id: 3063603-6

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Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNA

Huerta-Sánchez, Emilia ; Jin, Xin ; Asan ; [et al.]

Springer Science and Business Media LLC ; 2014

In: Nature Vol. 512, No. 7513 ( 2014-8), p. 194-197

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In: Nature, Springer Science and Business Media LLC, Vol. 512, No. 7513 ( 2014-8), p. 194-197

Type of Medium: Online Resource

ISSN: 0028-0836 , 1476-4687

URL: Article

DOI: 10.1038/nature13408

RVK:

TA 1000

RVK:

UA 1000

RVK:

WA 15000

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2014

detail.hit.zdb_id: 120714-3

detail.hit.zdb_id: 1413423-8

SSG: 11

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Shared signatures of social stress and aging in peripheral blood mononuclear cell gene expression profiles

Snyder‐Mackler, Noah ; Somel, Mehmet ; Tung, Jenny

Wiley ; 2014

In: Aging Cell Vol. 13, No. 5 ( 2014-10), p. 954-957

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In: Aging Cell, Wiley, Vol. 13, No. 5 ( 2014-10), p. 954-957

Type of Medium: Online Resource

ISSN: 1474-9718 , 1474-9726

URL: Issue

URL: Article

DOI: 10.1111/acel.2014.13.issue-5

DOI: 10.1111/acel.12239

Language: English

Publisher: Wiley

Publication Date: 2014

detail.hit.zdb_id: 2099130-7

SSG: 12

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Disruption of an Evolutionarily Novel Synaptic Expression Pattern in Autism

Liu, Xiling ; Han, Dingding ; Somel, Mehmet ; [et al.]

Public Library of Science (PLoS) ; 2016

In: PLOS Biology Vol. 14, No. 9 ( 2016-9-29), p. e1002558-

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In: PLOS Biology, Public Library of Science (PLoS), Vol. 14, No. 9 ( 2016-9-29), p. e1002558-

Type of Medium: Online Resource

ISSN: 1545-7885

URL: Article

DOI: 10.1371/journal.pbio.1002558

DOI: 10.1371/journal.pbio.1002558.g001

DOI: 10.1371/journal.pbio.1002558.g002

DOI: 10.1371/journal.pbio.1002558.g003

DOI: 10.1371/journal.pbio.1002558.g004

DOI: 10.1371/journal.pbio.1002558.s001

DOI: 10.1371/journal.pbio.1002558.s002

DOI: 10.1371/journal.pbio.1002558.s003

DOI: 10.1371/journal.pbio.1002558.s004

DOI: 10.1371/journal.pbio.1002558.s005

DOI: 10.1371/journal.pbio.1002558.s006

DOI: 10.1371/journal.pbio.1002558.s007

DOI: 10.1371/journal.pbio.1002558.s008

DOI: 10.1371/journal.pbio.1002558.s009

DOI: 10.1371/journal.pbio.1002558.s010

DOI: 10.1371/journal.pbio.1002558.s011

DOI: 10.1371/journal.pbio.1002558.s012

DOI: 10.1371/journal.pbio.1002558.s013

DOI: 10.1371/journal.pbio.1002558.s014

DOI: 10.1371/journal.pbio.1002558.s015

DOI: 10.1371/journal.pbio.1002558.s016

DOI: 10.1371/journal.pbio.1002558.s017

DOI: 10.1371/journal.pbio.1002558.s018

DOI: 10.1371/journal.pbio.1002558.s019

DOI: 10.1371/journal.pbio.1002558.s020

DOI: 10.1371/journal.pbio.1002558.s021

DOI: 10.1371/journal.pbio.1002558.s022

DOI: 10.1371/journal.pbio.1002558.s023

DOI: 10.1371/journal.pbio.1002558.s024

DOI: 10.1371/journal.pbio.1002558.s025

DOI: 10.1371/journal.pbio.1002558.s026

DOI: 10.1371/journal.pbio.1002558.s027

DOI: 10.1371/journal.pbio.1002558.s028

DOI: 10.1371/journal.pbio.1002558.s029

DOI: 10.1371/journal.pbio.1002558.s030

DOI: 10.1371/journal.pbio.1002558.s031

DOI: 10.1371/journal.pbio.1002558.s032

Language: English

Publisher: Public Library of Science (PLoS)

Publication Date: 2016

detail.hit.zdb_id: 2126773-X

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