In:
FEBS Letters, Wiley, Vol. 153, No. 1 ( 1983-03-07), p. 103-107
Abstract:
N 6 ‐Phenylisopropyladenosine was employed in the absence of endogenous adenosine to explore the influence exerted by the R‐site over the antagonistic interaction of insulin and catecholamines on several parameters of fat cell metabolism. When no hormones were present, N 6 ‐phenylisopropyladenosine had little or no effect; however, the nucleoside potentiated insulin inhibition of catecholamine‐stimulated events, such as lipolysis, and conversely, diminished or blocked catecholamine inhibition of insulin‐stimulated processes, such as 2‐deoxyglucose uptake, glucose oxidation and esterification, even under conditions where N 6 ‐phenylisopropyladenosine, alone, was ineffective in reversing catecholamine actions.
Type of Medium:
Online Resource
ISSN:
0014-5793
,
1873-3468
DOI:
10.1016/0014-5793(83)80127-6
Language:
English
Publisher:
Wiley
Publication Date:
1983
detail.hit.zdb_id:
1460391-3
SSG:
12
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