In:
Antioxidants, MDPI AG, Vol. 9, No. 7 ( 2020-07-21), p. 641-
Abstract:
Metabolic syndrome (MetS) is a well established risk factor for cardiovascular (CV) diseases. In addition, several studies indicate that MetS correlates with the increased risk of cancer in adults. The mechanisms linking MetS and cancer are not fully understood. Several risk factors involved in MetS are also cancer risk factors, such as the consumption of high calorie-food or high fat intake, low fibre intake, and sedentary lifestyle. Other common aspects of both cancer and MetS are oxidative stress and inflammation. In addition, some anticancer treatments can induce cardiotoxicity, including, for instance, left ventricular (LV) dysfunction and heart failure (HF), endothelial dysfunction and hypertension. In this review, we analyse several aspects of MetS, cancer and cardiotoxicity from anticancer drugs. In particular, we focus on oxidative stress in ageing, cancer and CV diseases, and we analyse the connections among CV risk factors, cancer and cardiotoxicity from anticancer drugs.
Type of Medium:
Online Resource
ISSN:
2076-3921
DOI:
10.3390/antiox9070641
Language:
English
Publisher:
MDPI AG
Publication Date:
2020
detail.hit.zdb_id:
2704216-9
SSG:
15,3
Bookmarklink