In:
Journal of Bacteriology, American Society for Microbiology, Vol. 120, No. 3 ( 1974-12), p. 1284-1292
Abstract:
Loci for resistance to several antibiotics in laboratory-derived strains of Neisseria gonorrhoeae were mapped by genetic transformation. Genes for high-level resistance to streptomycin ( str ) and spectinomycin ( spc ) and for low-level resistance to tetracycline ( tet ) and chloramphenicol ( chl ) were linked. Also, a locus for high-level resistance to rifampin ( rif ) was linked to str and tet . The apparent order was rif... str... tet... chl... spc . Loci for resistance to other antibiotics (penicillin, erythromycin) were transferred independently of each other and were not linked to the cluster around str . Similar linkage relationships were found with str, tet, chl , and spc loci obtained from naturally occurring (clinical) isolates of N. gonorrhoeae .
Type of Medium:
Online Resource
ISSN:
0021-9193
,
1098-5530
DOI:
10.1128/jb.120.3.1284-1292.1974
Language:
English
Publisher:
American Society for Microbiology
Publication Date:
1974
detail.hit.zdb_id:
2968-3
detail.hit.zdb_id:
1481988-0
SSG:
12
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