In:
Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 146, No. Suppl_1 ( 2022-11-08)
Abstract:
Introduction: Catheter ablation is a well-established treatment option for patients with atrial fibrillation (AF). We aimed to evaluate the impact of baseline AF events frequency, duration, and symptoms severity on AF recurrence Methods: The study included patients with first time AF ablation at a tertiary US center between 2013 and 2021. Patients prospectively completed a baseline and follow up survey (12 months) for patients reported outcomes assessing AF frequency, duration, and severity (AF symptom severity scale). The duration and frequency scores ranged between 0 and 9 (no AF to continuous). Patients were grouped into quartiles (Q1-Q4) based on their baseline scores. The quartile with the lowest score was used as the reference group. AF recurrence was assessed during follow up Results: A total of 2150 patients (age 65±9 yrs, 75% male, and 65% paroxysmal AF). At one year, only 17% of patients had AF recurrence. Frequency score: The risk for AF recurrence was similar between Q2/Q3 when compared with Q1 (Q2: HR=0.82, p=0.15, Q3: HR=0.98, p=0.91; Figure Upper), whereas patients in Q4 (score of 10) had a significant risk increase compared to Q1 (HR=1.28, p=0.047; Figure Left). Duration score: The risk for AF recurrence (Figure Middle) was similar between Q2 and Q1 (HR=0.97, p=0.83), was higher for Q3 (score ≥6 and 〈 9; HR=1.39, p=0.015), and highest for Q4 (score ≥9; HR=1.46, p=0.002). Severity score: The baseline severity score did not predict or correlate with AF recurrence during FU. Ablation resulted in a significant reduction (≥10%) in each score category. The highest benefit was seen among the Frequency category (96% of the patients had an improvement in their score at one year), followed by duration (90%) and severity (89%) Conclusions: Patients’ reported high frequency, and/or high duration were associated with increased risk for AF recurrence. Following ablation, improvement in all patients’ reported outcomes was significantly higher than reported AF free survivals
Type of Medium:
Online Resource
ISSN:
0009-7322
,
1524-4539
DOI:
10.1161/circ.146.suppl_1.15414
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2022
detail.hit.zdb_id:
1466401-X
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