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Figure 8 from: Burgstaller S, Leeb C, Ringler M, Gollmann G (2021) Demography and spatial activity of fire salamanders, Salamandra salamandra (Linnaeus, 1758), in two contrasting habitats in the Vienna Woods. Herpetozoa 34: 23-34. https://doi.org/10.3897/herpetozoa.34.e58496

Burgstaller, Stephan ; Leeb, Christoph ; Ringler, Max ; [et al.]

Pensoft Publishers ; 2021

In: Herpetozoa Vol. 34 ( 2021-02-03), p. 23-34

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In: Herpetozoa, Pensoft Publishers, Vol. 34 ( 2021-02-03), p. 23-34

Abstract: Understanding population dynamics is vital in amphibian conservation. To compare demography and movements, we conducted a capture-recapture study over three spring seasons in two populations of Salamandra salamandra in the Vienna Woods. The study sites differ in topography, vegetation, and the type of breeding waters. Population density in a beech forest traversed by a stream was more than twice as high as in an oak-hornbeam forest with temporary pools. Movement distances were on average higher at the latter site whereas home range estimates were similar for both sites. The sexes did not differ significantly in the observed movement patterns at either site. Annual apparent survival was mostly high (~0.85), but the estimate for females from the low-density site was lower (~0.60), indicating a higher rate of emigration or mortality.

Type of Medium: Online Resource

ISSN: 2682-955X , 1013-4425

URL: Article

DOI: 10.3897/herpetozoa.34.e58496

DOI: 10.3897/herpetozoa.34.e58496.figure1

DOI: 10.3897/herpetozoa.34.e58496.figure2

DOI: 10.3897/herpetozoa.34.e58496.figure3

DOI: 10.3897/herpetozoa.34.e58496.figure4

DOI: 10.3897/herpetozoa.34.e58496.figure5

DOI: 10.3897/herpetozoa.34.e58496.figure6

DOI: 10.3897/herpetozoa.34.e58496.figure7

DOI: 10.3897/herpetozoa.34.e58496.figure8

Language: Unknown

Publisher: Pensoft Publishers

Publication Date: 2021

detail.hit.zdb_id: 2474932-1

SSG: 12

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Endovascular thrombectomy for acute ischaemic stroke with established large infarct: multicentre, open-label, randomised trial

Bendszus, Martin ; Fiehler, Jens ; Subtil, Fabien ; [et al.]

Elsevier BV ; 2023

In: The Lancet Vol. 402, No. 10414 ( 2023-11), p. 1753-1763

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In: The Lancet, Elsevier BV, Vol. 402, No. 10414 ( 2023-11), p. 1753-1763

Type of Medium: Online Resource

ISSN: 0140-6736

URL: Article

DOI: 10.1016/S0140-6736(23)02032-9

RVK:

XA 10000

Language: English

Publisher: Elsevier BV

Publication Date: 2023

detail.hit.zdb_id: 2067452-1

detail.hit.zdb_id: 3306-6

detail.hit.zdb_id: 1476593-7

SSG: 5,21

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Switching from boosted PIs to dolutegravir in HIV-infected patients with high cardiovascular risk: 48 week effects on subclinical cardiovascular disease

Gonzalez-Cordon, Ana ; Assoumou, Lambert ; Camafort, Miguel ; [et al.]

Oxford University Press (OUP) ; 2020

In: Journal of Antimicrobial Chemotherapy Vol. 75, No. 11 ( 2020-11-01), p. 3334-3343

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In: Journal of Antimicrobial Chemotherapy, Oxford University Press (OUP), Vol. 75, No. 11 ( 2020-11-01), p. 3334-3343

Abstract: Switching from boosted PIs to dolutegravir in virologically suppressed HIV-infected patients with high cardiovascular risk significantly decreased total cholesterol and other proatherogenic lipid fractions at 48 weeks. The impact of this strategy on subclinical cardiovascular disease is unknown. Methods NEAT022 is a European, multicentre, open-label, randomized, non-inferiority trial. HIV-infected adults aged & gt;50 years or with a Framingham score & gt;10% were eligible if plasma HIV RNA was & lt;50 copies/mL for & gt;24 weeks on a boosted PI-based regimen. Patients were randomized 1:1 to switch from boosted PIs to dolutegravir or to continue on boosted PIs. Common carotid arteries intima–media thickness (CIMT) and pulse wave velocity (PWV) were measured following a standardized protocol in a subgroup of NEAT022 study participants at baseline and at Week 48. Results One hundred and fifty-six patients participated in the ultrasonography and arterial stiffness substudies, respectively. In each substudy, population characteristics did not differ between arms and matched those of the main study. At 48 weeks, patients who switched to dolutegravir had lower mean progression of both right (+4 versus +14.6 μm) and left (−6.1 versus +1.6 μm) CIMT and also a smaller increase in mean PWV (+0.18 versus +0.39 m/s) than patients continuing on boosted PIs, although differences were not statistically significant. CIMT trends were consistent across Framingham score, age and country. Inconsistent effects were seen in arterial stiffness. Conclusions Relative to continuing on boosted PIs, switching to dolutegravir in virologically suppressed patients with high cardiovascular risk showed consistent favourable although non-significant trends on CIMT progression at 48 weeks.

Type of Medium: Online Resource

ISSN: 0305-7453 , 1460-2091

URL: Article

DOI: 10.1093/jac/dkaa292

Language: English

Publisher: Oxford University Press (OUP)

Publication Date: 2020

detail.hit.zdb_id: 1467478-6

SSG: 15,3

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Impact of Right Ventricular Pressure Load After Repair of Tetralogy of Fallot

Latus, Heiner ; Stammermann, Jana ; Voges, Inga ; [et al.]

Ovid Technologies (Wolters Kluwer Health) ; 2022

In: Journal of the American Heart Association Vol. 11, No. 7 ( 2022-04-05)

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In: Journal of the American Heart Association, Ovid Technologies (Wolters Kluwer Health), Vol. 11, No. 7 ( 2022-04-05)

Abstract: Right ventricular outflow tract (RVOT) stenosis after repair of tetralogy of Fallot has been linked with favorable right ventricular remodeling but adverse outcomes. The aim of our study was to assess the hemodynamic impact and prognostic relevance of right ventricular pressure load in this population. Methods and Results A total of 296 patients with repaired tetralogy of Fallot (mean age, 17.8±7.9 years) were included in a prospective cardiovascular magnetic resonance multicenter study. Myocardial strain was quantified by feature tracking technique at study entry. Follow‐up, including the need for pulmonary valve replacement, was assessed. The combined end point consisted of ventricular tachycardia and cardiac death. A higher echocardiographic RVOT peak gradient was significantly associated with smaller right ventricular volumes and less pulmonary regurgitation, but lower biventricular longitudinal strain. During a follow‐up of 10.1 (0.1–12.9) years, the primary end point was reached in 19 of 296 patients (cardiac death, n=6; sustained ventricular tachycardia, n=2; and nonsustained ventricular tachycardia, n=11). A higher RVOT gradient was associated with the combined outcome (hazard ratio [HR], 1.03; 95% CI, 1.00–1.06; P =0.026), and a cutoff gradient of ≥25 mm Hg was predictive for cardiovascular events (HR, 3.69; 95% CI, 1.47–9.27; P =0.005). In patients with pulmonary regurgitation ≥25%, a mild residual RVOT gradient (15–30 mm Hg) was not associated with a lower risk for pulmonary valve replacement. Conclusions Higher RVOT gradients were associated with less pulmonary regurgitation and smaller right ventricular dimensions but were related to reduced biventricular strain and emerged as univariate predictors of adverse events. Mild residual pressure gradients did not protect from pulmonary valve replacement. These results may have implications for the indication for RVOT reintervention in this population.

Type of Medium: Online Resource

ISSN: 2047-9980

URL: Article

DOI: 10.1161/JAHA.121.022694

Language: English

Publisher: Ovid Technologies (Wolters Kluwer Health)

Publication Date: 2022

detail.hit.zdb_id: 2653953-6

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Somatic Development in Children with Congenital Heart Defects

Poryo, Martin ; Paes, Laura Antonia ; Pickardt, Thomas ; [et al.]

Elsevier BV ; 2018

In: The Journal of Pediatrics Vol. 192 ( 2018-01), p. 136-143.e4

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In: The Journal of Pediatrics, Elsevier BV, Vol. 192 ( 2018-01), p. 136-143.e4

Type of Medium: Online Resource

ISSN: 0022-3476

URL: Article

DOI: 10.1016/j.jpeds.2017.09.059

Language: English

Publisher: Elsevier BV

Publication Date: 2018

detail.hit.zdb_id: 2005245-5

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Natalizumab treatment shows low cumulative probabilities of confirmed disability worsening to EDSS milestones in the long-term setting

Trojano, Maria ; Butzkueven, Helmut ; Kappos, Ludwig ; [et al.]

Elsevier BV ; 2018

In: Multiple Sclerosis and Related Disorders Vol. 24 ( 2018-08), p. 11-19

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In: Multiple Sclerosis and Related Disorders, Elsevier BV, Vol. 24 ( 2018-08), p. 11-19

Type of Medium: Online Resource

ISSN: 2211-0348

URL: Article

DOI: 10.1016/j.msard.2018.04.020

Language: English

Publisher: Elsevier BV

Publication Date: 2018

detail.hit.zdb_id: 2645330-7

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Uveitis manifestations in patients of the Swiss Inflammatory Bowel Disease Cohort Study

Biedermann, Luc ; Renz, Laura ; Fournier, Nicolas ; [et al.]

SAGE Publications ; 2019

In: Therapeutic Advances in Gastroenterology Vol. 12 ( 2019-01), p. 175628481986514-

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In: Therapeutic Advances in Gastroenterology, SAGE Publications, Vol. 12 ( 2019-01), p. 175628481986514-

Abstract: The knowledge about risk factors for the onset of uveitis manifestations in patients with inflammatory bowel disease (IBD) is still limited. Here, we aimed to provide an overview of the clinical factors associated with the onset of uveitis in the Swiss IBD Cohort Study (SIBDCS). Methods: We included epidemiological and clinical data from 1840 patients with Crohn’s disease (CD) and 1426 patients with ulcerative colitis (UC) followed up in the SIBDCS between 2006 and 2018. Associations between disease characteristics and uveitis were assessed in univariate and multivariate analyses. Results: Overall, we identified 285 patients with uveitis. Uveitis was more frequent in patients with CD (11.1%; 205 of 1635) than UC (5.6%; 80 of 1346; odds ratio 2.11, p 〈 0.001). The occurrence of uveitis manifestations in patients with UC and CD was significantly associated with the onset of other extraintestinal manifestations, also in multivariate analyses. The onset of uveitis was associated with the hallmark features of severe disease in both CD and UC, including a higher clinical disease activity index and the use of immunomodulators or calcineurin inhibitors. In CD, uveitis was more frequent in females and showed a positive correlation with a positive family history of IBD. Conclusions: Our data demonstrate that uveitis in IBD occurs more often in CD as well as in women and is associated with a more severe disease course. This might guide physicians’ awareness in at-risk patients to the presence of uveitis extraintestinal manifestations and help to improve patient care.

Type of Medium: Online Resource

ISSN: 1756-2848 , 1756-2848

URL: Article

DOI: 10.1177/1756284819865142

Language: English

Publisher: SAGE Publications

Publication Date: 2019

detail.hit.zdb_id: 2440710-0

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Abdominal pain in patients with inflammatory bowel disease: association with single-nucleotide polymorphisms prevalent in irritable bowel syndrome and clinical management

Ledergerber, Martina ; Lang, Brian M. ; Heinrich, Henriette ; [et al.]

Springer Science and Business Media LLC ; 2021

In: BMC Gastroenterology Vol. 21, No. 1 ( 2021-02-05)

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In: BMC Gastroenterology, Springer Science and Business Media LLC, Vol. 21, No. 1 ( 2021-02-05)

Abstract: Abdominal pain is a frequent symptom in patients with inflammatory bowel disease (IBD) including Crohn’s disease (CD) and ulcerative colitis (UC). Pain can result from ongoing inflammation or functional disorders imitating irritable bowel syndrome (IBS). Several single-nucleotide polymorphisms (SNPs) have been associated with IBS. However, the impact of IBS genetics on the clinical course of IBD, especially pain levels of patients remains unclear. Methods Data of 857 UC and 1206 CD patients from the Swiss IBD Cohort Study were analysed. We tested the association of the maximum of the abdominal pain item of disease activity indices in UC and CD over the study period with 16 IBS-associated SNPs, using multivariate ANOVA models. Results In UC patients, the SNPs rs1042713 (located on the ADRB2 gene) and rs4663866 (close to the HES6 gene) were associated with higher abdominal pain levels ( P = 0.044; P = 0.037, respectively). Abdominal pain was not associated with any markers of patient management in a model adjusted for confounders. In CD patients, higher levels of abdominal pain correlated with the number of physician contacts ( P 〈 10 –15 ), examinations ( P 〈 10 –12 ), medical therapies ( P = 0.023) and weeks of hospitalisation ( P = 0.0013) in a multivariate model. Conclusions We detected an association between maximal abdominal pain in UC patients and two IBS-associated SNPs. Abdominal pain levels had a pronounced impact on diagnostic and therapeutic procedures in CD but not in UC patients.

Type of Medium: Online Resource

ISSN: 1471-230X

URL: Article

DOI: 10.1186/s12876-021-01622-x

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2021

detail.hit.zdb_id: 2041351-8

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The Relevance of Vitamin and Iron Deficiency in Patients with Inflammatory Bowel Diseases in Patients of the Swiss IBD Cohort

Madanchi, Matiar ; Fagagnini, Stefania ; Fournier, Nicolas ; [et al.]

Oxford University Press (OUP) ; 2018

In: Inflammatory Bowel Diseases Vol. 24, No. 8 ( 2018-07-12), p. 1768-1779

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In: Inflammatory Bowel Diseases, Oxford University Press (OUP), Vol. 24, No. 8 ( 2018-07-12), p. 1768-1779

Type of Medium: Online Resource

ISSN: 1078-0998 , 1536-4844

URL: Article

DOI: 10.1093/ibd/izy054

Language: English

Publisher: Oxford University Press (OUP)

Publication Date: 2018

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Colectomy Rates in Ulcerative Colitis are Low and Decreasing: 10-year Follow-up Data From the Swiss IBD Cohort Study

Parragi, Levente ; Fournier, N ; Zeitz, Jonas ; [et al.]

Oxford University Press (OUP) ; 2018

In: Journal of Crohn's and Colitis Vol. 12, No. 7 ( 2018-06-28), p. 811-818

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In: Journal of Crohn's and Colitis, Oxford University Press (OUP), Vol. 12, No. 7 ( 2018-06-28), p. 811-818

Type of Medium: Online Resource

ISSN: 1873-9946 , 1876-4479

URL: Article

DOI: 10.1093/ecco-jcc/jjy040

Language: English

Publisher: Oxford University Press (OUP)

Publication Date: 2018

detail.hit.zdb_id: 2389631-0

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