In:
BioMed Research International, Hindawi Limited, Vol. 2013 ( 2013), p. 1-10
Abstract:
Purpose . To evaluate training induced metabolic changes noninvasively with magnetic resonance spectroscopy (-MRS) for measuring muscle fibre type adaptation. Methods . Eleven volunteers underwent a 24-week training, consisting of speed-strength, endurance, and detraining (each 8 weeks). Prior to and following each training period, needle biopsies and -MRS of the resting gastrocnemius muscle were performed. Fibre type distribution was analyzed histologically and tested for correlation with the ratios of high energy phosphates ([PCr]/[] , [PCr]/[ β ATP] and [PCr + ] /[ β ATP]). The correlation between the changes of the -MRS parameters during training and the resulting changes in fibre composition were also analysed. Results . We observed an increased type-II-fibre proportion after speed-strength and detraining. After endurance training the percentage of fast-twitch fibres was reduced. The progression of the [PCr]/[] -ratio was similar to that of the fast-twitch fibres during the training. We found a correlation between the type-II-fibre proportion and [PCr] /[] (, ) or [PCr] /[ β ATP] (, ); the correlations between its changes (delta) and the fibre-shift were significant as well (delta[PCr] /[] , delta[PCr] /[ β ATP] , ). Conclusion . Shifts in fibre type composition and high energy phosphate metabolite content covary in human gastrocnemius muscle. Therefore -MRS might be a feasible method for noninvasive monitoring of exercise-induced fibre type transformation.
Type of Medium:
Online Resource
ISSN:
2314-6133
,
2314-6141
Language:
English
Publisher:
Hindawi Limited
Publication Date:
2013
detail.hit.zdb_id:
2698540-8
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