In:
Chemistry & Biodiversity, Wiley, Vol. 14, No. 11 ( 2017-11)
Abstract:
Chemical compositions, antioxidative, antimicrobial, anti‐inflammatory, and cytotoxic activities of essential oils extracted from four common Curcuma species ( Curcuma longa , Curcuma phaeocaulis , Curcuma wenyujin , and Curcuma kwangsiensis ) rhizomes in P. R. China are comparatively studied. In total, 47, 49, 35, and 30 compounds are identified in C . longa , C . phaeocaulis , C . wenyujin , and C . kwangsiensis essential oils by GC/MS, and their richest compounds are ar ‐turmerone (21.67%), elemenone (19.41%), curdione (40.23%) and (36.47%), respectively. Moreover, C . kwangsiensis essential oils display the strongest DPPH (2,2‐diphenyl‐1‐picrylhydrazyl) radical‐scavenging activity ( IC 50 , 3.47 μg/ml), much higher than ascorbic acid (6.50 μg/ml). C . phaeocaulis oils show the best antibacterial activities against Escherichia coli ( MIC , 235.54 μg/ml), Pseudomonas aeruginosa (391.31 μg/ml) and Staphylococcus aureus (378.36 μg/ml), while C . wenyujin and C . kwangsiensis oils show optimum activities against Candida albicans (208.61 μg/ml) and Saccharomyces cerevisiae (193.27 μg/ml), respectively. C. phaeocaulis ( IC 50 , 4.63 μg/ml) and C. longa essential oils (73.05 μg/ml) have the best cytotoxicity against LNCaP and HepG2, respectively. C . kwangsiensis oils also exhibit the strongest anti‐inflammatory activities by remarkably down‐regulating expression of COX‐2 and TNF‐ α . Therefore, due to their different chemical compositions and bioactivities, traditional Chinese Curcuma herbs should be differentially served as natural additives for food, pharmaceutical, and cosmetic.
Type of Medium:
Online Resource
ISSN:
1612-1872
,
1612-1880
DOI:
10.1002/cbdv.201700280
Language:
English
Publisher:
Wiley
Publication Date:
2017
detail.hit.zdb_id:
2139001-0
SSG:
12
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