In:
Journal of Leukocyte Biology, Oxford University Press (OUP), Vol. 54, No. 5 ( 1993-11-01), p. 504-512
Abstract:
Soluble FCγ receptors have been identified in biological fluids of mice and humans. They are produced either by alternative splicing of the exon encoding the transmembrane region of the receptor (FcγRII) or by proteolytic cleavage at the cell membrane (FCγRII and FC7RIII). They inhibit B cell proliferation and immunoglobulin production. Their concentrations in plasma seem to be modified during the development of certain diseases, as for instance in multiple myeloma, where plasma concentrations oi soluble FCγKIll are correlated with the stage of the disease.
Type of Medium:
Online Resource
ISSN:
0741-5400
,
1938-3673
DOI:
10.1002/jlb.54.5.504
Language:
English
Publisher:
Oxford University Press (OUP)
Publication Date:
1993
detail.hit.zdb_id:
2026833-6
SSG:
12
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