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1

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Iterative Focused Screening with Biological Fingerprints Identifies Selective Asc1 Inhibitors Distinct from Traditional High Throughput Screening

Kutchukian, Peter S. ; Warren, Lee ; Magliaro, Brian C. ; [et al.]

American Chemical Society (ACS) ; 2017

In: ACS Chemical Biology Vol. 12, No. 2 ( 2017-02-17), p. 519-527

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In: ACS Chemical Biology, American Chemical Society (ACS), Vol. 12, No. 2 ( 2017-02-17), p. 519-527

Type of Medium: Online Resource

ISSN: 1554-8929 , 1554-8937

URL: Article

DOI: 10.1021/acschembio.6b00913

DOI: 10.1021/acschembio.6b00913.s001

Language: English

Publisher: American Chemical Society (ACS)

Publication Date: 2017

detail.hit.zdb_id: 2221735-6

SSG: 12

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2

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Screening of HIV-1 Protease Using a Combination of an Ultra-High-Throughput Fluorescent-Based Assay and RapidFire Mass Spectrometry

Meng, Juncai ; Lai, Ming-Tain ; Munshi, Vandna ; [et al.]

Elsevier BV ; 2015

In: SLAS Discovery Vol. 20, No. 5 ( 2015-06), p. 606-615

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In: SLAS Discovery, Elsevier BV, Vol. 20, No. 5 ( 2015-06), p. 606-615

Type of Medium: Online Resource

ISSN: 2472-5552

URL: Article

DOI: 10.1177/1087057115570838

Language: English

Publisher: Elsevier BV

Publication Date: 2015

detail.hit.zdb_id: 2886402-5

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3

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Prospective Assessment of Virtual Screening Heuristics Derived Using a Novel Fusion Score

Pertusi, Dante A. ; O’Donnell, Gregory ; Homsher, Michelle F. ; [et al.]

Elsevier BV ; 2017

In: SLAS Discovery Vol. 22, No. 8 ( 2017-09), p. 995-1006

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In: SLAS Discovery, Elsevier BV, Vol. 22, No. 8 ( 2017-09), p. 995-1006

Type of Medium: Online Resource

ISSN: 2472-5552

URL: Article

DOI: 10.1177/2472555217706058

Language: English

Publisher: Elsevier BV

Publication Date: 2017

detail.hit.zdb_id: 2886402-5

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4

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Use of High-Throughput Mass Spectrometry to Reduce False Positives in Protease uHTS Screens

Adam, Gregory C. ; Meng, Juncai ; Rizzo, Joseph M. ; [et al.]

Elsevier BV ; 2015

In: SLAS Discovery Vol. 20, No. 2 ( 2015-02), p. 212-222

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In: SLAS Discovery, Elsevier BV, Vol. 20, No. 2 ( 2015-02), p. 212-222

Type of Medium: Online Resource

ISSN: 2472-5552

URL: Article

DOI: 10.1177/1087057114555832

Language: English

Publisher: Elsevier BV

Publication Date: 2015

detail.hit.zdb_id: 2886402-5

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5

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Hypothalamic Neuropeptide S receptor blockade decreases discriminative cue-induced reinstatement of cocaine seeking in the rat

Kallupi, Marsida ; de Guglielmo, Giordano ; Cannella, Nazzareno ; [et al.]

Springer Science and Business Media LLC ; 2013

In: Psychopharmacology Vol. 226, No. 2 ( 2013-3), p. 347-355

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In: Psychopharmacology, Springer Science and Business Media LLC, Vol. 226, No. 2 ( 2013-3), p. 347-355

Type of Medium: Online Resource

ISSN: 0033-3158 , 1432-2072

URL: Article

DOI: 10.1007/s00213-012-2910-y

RVK:

CL 1000

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2013

detail.hit.zdb_id: 2066933-1

SSG: 15,3

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6

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Pharmacological Validation of Candidate Causal Sleep Genes Identified in an N2 Cross

Brunner, Joseph I. ; Gotter, Anthony L. ; Millstein, Joshua ; [et al.]

Informa UK Limited ; 2011

In: Journal of Neurogenetics Vol. 25, No. 4 ( 2011-12), p. 167-181

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In: Journal of Neurogenetics, Informa UK Limited, Vol. 25, No. 4 ( 2011-12), p. 167-181

Type of Medium: Online Resource

ISSN: 0167-7063 , 1563-5260

URL: Article

DOI: 10.3109/01677063.2011.628426

Language: English

Publisher: Informa UK Limited

Publication Date: 2011

detail.hit.zdb_id: 2031011-0

SSG: 12

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7

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Cross-Modulation and Molecular Interaction at the Ca v 3.3 Protein between the Endogenous Lipids and the T-Type Calcium Channel Antagonist TTA-A2.

Cazade, Magali ; Nuss, Cindy E. ; Bidaud, Isabelle ; [et al.]

American Society for Pharmacology & Experimental Therapeutics (ASPET) ; 2014

In: Molecular Pharmacology Vol. 85, No. 2 ( 2014-02), p. 218-225

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In: Molecular Pharmacology, American Society for Pharmacology & Experimental Therapeutics (ASPET), Vol. 85, No. 2 ( 2014-02), p. 218-225

Type of Medium: Online Resource

ISSN: 0026-895X , 1521-0111

URL: Article

DOI: 10.1124/mol.113.089581

Language: English

Publisher: American Society for Pharmacology & Experimental Therapeutics (ASPET)

Publication Date: 2014

detail.hit.zdb_id: 1475030-2

SSG: 15,3

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8

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Presynaptic HCN1 channels regulate CaV3.2 activity and neurotransmission at select cortical synapses

Huang, Zhuo ; Lujan, Rafael ; Kadurin, Ivan ; [et al.]

Springer Science and Business Media LLC ; 2011

In: Nature Neuroscience Vol. 14, No. 4 ( 2011-4), p. 478-486

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In: Nature Neuroscience, Springer Science and Business Media LLC, Vol. 14, No. 4 ( 2011-4), p. 478-486

Type of Medium: Online Resource

ISSN: 1097-6256 , 1546-1726

URL: Article

DOI: 10.1038/nn.2757

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2011

detail.hit.zdb_id: 1494955-6

SSG: 12

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9

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Discovery of benzofuran propanoic acid GPR120 agonists: From uHTS hit to mechanism-based pharmacodynamic effects

Lombardo, Matthew ; Bender, Kate ; London, Clare ; [et al.]

Elsevier BV ; 2016

In: Bioorganic & Medicinal Chemistry Letters Vol. 26, No. 23 ( 2016-12), p. 5724-5728

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In: Bioorganic & Medicinal Chemistry Letters, Elsevier BV, Vol. 26, No. 23 ( 2016-12), p. 5724-5728

Type of Medium: Online Resource

ISSN: 0960-894X

URL: Article

DOI: 10.1016/j.bmcl.2016.10.054

RVK:

VA 2620

Language: English

Publisher: Elsevier BV

Publication Date: 2016

detail.hit.zdb_id: 1501505-1

SSG: 15,3

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10

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Discovery of 4-arylquinoline-2-carboxamides, highly potent and selective class of mGluR2 negative allosteric modulators: From HTS to activity in animal models

Shu, Youheng ; Diamond, Tracy L. ; Hershey, James C. ; [et al.]

Elsevier BV ; 2020

In: Bioorganic & Medicinal Chemistry Letters Vol. 30, No. 9 ( 2020-05), p. 127066-

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In: Bioorganic & Medicinal Chemistry Letters, Elsevier BV, Vol. 30, No. 9 ( 2020-05), p. 127066-

Type of Medium: Online Resource

ISSN: 0960-894X

URL: Article

DOI: 10.1016/j.bmcl.2020.127066

RVK:

VA 2620

Language: English

Publisher: Elsevier BV

Publication Date: 2020

detail.hit.zdb_id: 1501505-1

SSG: 15,3

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Berlin Brandenburg