In:
Journal of Veterinary Medicine Series A, Wiley, Vol. 37, No. 1-10 ( 1990-02-12), p. 737-746
Abstract:
The effects of medetomidine [20 and 40μg/kg of body weight (BWT) i. m.] followed by sodium pentobarbital were assessed and compared with the effects of xylazine (1mg/kg of BWT i. m.) in three groups each of 6 dogs. The effects of atipamezole as a specific antidote after anaesthesia were also studied. Medetomidine produced a reliable sedation which was clinically comparable with the xylazine premedication. 40μg/kg medetomidine induced lower induction (non‐significantly), total (p 〈 0. 05), anaesthetic (non‐significantly) and anaesthetic per hour (non‐significantly) doses of Na pentobarbital compared to the 20μg/kg medetomidine and the xylazine protocols. No significant differences in the total number of re‐injections were found between the sedative protocols although a gradual increase in number of re‐injections per hour was observed. Significant decreases in heart and respiration rates were noticed during anaesthesia in all groups (p 〈 0. 01). The heart and respiration rates during anaesthesia in the 40μg/kg medetomidine group were always significantly lower compared to the xylazine group. Body temperature decreased gradually in time during anaesthesia in all groups (p 〈 0. 05 after 1 hour, p 〈 0. 01 after 2 and 3 hours) without significant differences between the groups. The extubation time in the medetomidine protocols without antagonisation was significantly greater (p 〈 0. 01) than the extubation time after antagonisation with atipamezole.
Type of Medium:
Online Resource
ISSN:
0931-184X
DOI:
10.1111/tbed.1990.37.issue-1-10
DOI:
10.1111/j.1439-0442.1990.tb00967.x
Language:
English
Publisher:
Wiley
Publication Date:
1990
detail.hit.zdb_id:
2414822-2
SSG:
22
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