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  • 1
    In: The Lancet Oncology, Elsevier BV, Vol. 24, No. 12 ( 2023-12), p. 1315-1318
    Type of Medium: Online Resource
    ISSN: 1470-2045
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2023
    detail.hit.zdb_id: 2049730-1
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  • 2
    Online Resource
    Online Resource
    Associacao Brasileira de Medicina e Cirurgia do Tornozelo e Pe (ABTPe) ; 2020
    In:  Journal of the Foot & Ankle Vol. 14, No. 2 ( 2020-08-30), p. 211-218
    In: Journal of the Foot & Ankle, Associacao Brasileira de Medicina e Cirurgia do Tornozelo e Pe (ABTPe), Vol. 14, No. 2 ( 2020-08-30), p. 211-218
    Abstract: In this technical tip, we present the case of an obese 17-year-old female diagnosed with a severe, rigid, and symptomatic flatfoot on a background of exuberant talocalcaneal and residual calcaneonavicular coalition. Through a technical modification of the fusion resection, both coalitions were quickly and safely removed with two single cuts of an oscillating saw, resecting a medial wedge through a medial approach, without the need for “peel-off” tarsal coalition resection. To protect and guide the resection osteotomy, one Freer elevator ws inserted under direct visualization on the patent posterolateral aspect of the subtalar joint posterior facet and a second elevator was positioned underneath the talar neck. Under fluoroscopic guidance, an osteotomy was performed connecting these two points. The patient also received a bone-block subtalar joint arthrodesis and a Cotton osteotomy. Good short-term alignment correction and functional outcome were achieved. Level of Evidence V; Therapeutic Studies; Expert Opinion.
    Type of Medium: Online Resource
    ISSN: 2675-2980
    Language: Unknown
    Publisher: Associacao Brasileira de Medicina e Cirurgia do Tornozelo e Pe (ABTPe)
    Publication Date: 2020
    detail.hit.zdb_id: 3040308-X
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  • 3
    In: Foot & Ankle Orthopaedics, SAGE Publications, Vol. 7, No. 1 ( 2022-01)
    Abstract: Ankle; Basic Sciences/Biologics; Hindfoot; Other Introduction/Purpose: Progressive collapsing foot deformity (PCFD), formerly termed Adult-Acquired Flatfoot Deformity (AAFD), is a complex 3-dimensional (3D) deformity characterized by peritalar subluxation (PTS) of the hindfoot through the triple joint complex. PTS severity is typically measured at the posterior facet of te subtalar joint, but recent studies have called this into question and presented the middle facet as a more accurate marker of deformity. The objective of this study was to use 3D distance mapping (DM) from weightbearing computed tomography (WBCT) images to assess PTS in PCFD patients and controls across the entire peritalar suface. We hypothesized that 3D DMs would identify the middle facet as a superior marker for PTS, as well as indicate increased extra-articular sinus tarsi and subfibular inpingements in PCFD patients. Methods: In this case control study, we analyzed WBCT data of 20 consecutive patients with flexible PCFD and 10 controls. Novel 3D distance mapping (DM) technique was used to objectively characterize joint coverage across the entire peritalar surface, including both articular (anterior, middle and posterior facets of the subtalar joint) and nonarticular regions (sisus tarsi and subfibular areas). Distance maps were measured in millimeters, and colored to highlight regions of interest. Distances from 1-4mm were shown in blue to indicate expected joint interaction/extra-articular proximity, while distances under 1mm were highlighted in yellow/red indicating close bone proximity consistent with joint space narrowing (articular) or impingement (extra-articular). Joint coverage was defined as percentage of articular area with DMs 〈 4 mm. Coverage Maps (CM) were built highlighting areas of adequate joint interaction (blue), joint subluxation (pink), and impingement (red). Comparisons were performed with independent t-tests or Wilcoxon tests. P values 〈 .05 were considered significant. Results: Overall, coverage was decreased in articular regions and impingement was increased in nonarticular regions of PCFD patients. Objectively, a significant 46.6% average increase in the uncoverage of the middle facet of the subtalar joint was observed in PCFD patients (p 〈 .001), consistent with signifcant middle facet subluxation when compared to controls. No significant similar uncoverage was identified in the anterior or posterior facets. Extra-articularly, an overall 98% increase in sinus tarsi coverage was identified in PCFD patients (p 〈 .007) with direct sinus tarsi impingement in 6 of 20 patients with PCFD, and one of the controls. Direct subfibular impingement was noted in only 1 of 20 PCFD patients, but subfibular space narrowing greater than 2 standard deviations was noted in 17 of 20 PCFD patients. Attached figures demonstrate examples of distance and coverage maps, as well as a comparative averaged assessment of peritalar surface coverage in PCFD and controls. Conclusion: Our study results revealed that when compared to controls PCFD patients demonstrated that a significant decrease in 3D measures of subtalar joint coverage was only identified in the middle facet, but not at the anterior or posterior facets. We also determined significantly decreased inter-bone distances in the sinus tarsi and subfibular regions of PCFD patients, confirming the occurrence of extra-articular impingement in those areas. We hope that the use of these 3D accurate and objective measures of distance (DM) and coverage maps (CM) of middle facet subluxation will support early detection of PCFD patients at high risk for progressive collapse.
    Type of Medium: Online Resource
    ISSN: 2473-0114 , 2473-0114
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2874570-X
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  • 4
    In: Injury, Elsevier BV, Vol. 52 ( 2021-07), p. S84-S88
    Type of Medium: Online Resource
    ISSN: 0020-1383
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2021
    detail.hit.zdb_id: 2011808-9
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  • 5
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2022
    In:  Pediatric Critical Care Medicine Vol. 23, No. 2 ( 2022-02), p. 99-108
    In: Pediatric Critical Care Medicine, Ovid Technologies (Wolters Kluwer Health), Vol. 23, No. 2 ( 2022-02), p. 99-108
    Abstract: Multidisciplinary PICU teams must effectively share information while caring for critically ill children. Clinical documentation helps clinicians develop a shared understanding of the patient’s diagnosis, which informs decision-making. However, diagnosis-related documentation in the PICU is understudied, thus limiting insights into how pediatric intensivists convey their diagnostic reasoning. Our objective was to describe how pediatric critical care clinicians document patients’ diagnoses at PICU admission. DESIGN: Retrospective mixed methods study describing diagnosis documentation in electronic health records. SETTING: Academic tertiary referral PICU. PATIENTS: Children 0–17 years old admitted nonelectively to a single PICU over 1 year. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: One hundred PICU admission notes for 96 unique patients were reviewed. In 87% of notes, both attending physicians and residents or advanced practice providers documented a primary diagnosis; in 13%, primary diagnoses were documented by residents or advanced practice providers alone. Most diagnoses (72%) were written as narrative free text, 11% were documented as problem lists/billing codes, and 17% used both formats. At least one rationale was documented to justify the primary diagnosis in 91% of notes. Diagnostic uncertainty was present in 52% of notes, most commonly suggested by clinicians’ use of words indicating uncertainty (65%) and documentation of differential diagnoses (60%). Clinicians’ integration and interpretation of information varied in terms of: 1) organization of diagnosis narratives, 2) use of contextual details to clarify the diagnosis, and 3) expression of diagnostic uncertainty. CONCLUSIONS: In this descriptive study, most PICU admission notes documented a rationale for the primary diagnosis and expressed diagnostic uncertainty. Clinicians varied widely in how they organized diagnostic information, used contextual details to clarify the diagnosis, and expressed uncertainty. Future work is needed to determine how diagnosis narratives affect clinical decision-making, patient care, and outcomes.
    Type of Medium: Online Resource
    ISSN: 1529-7535
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2022
    detail.hit.zdb_id: 2070997-3
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  • 6
    Online Resource
    Online Resource
    Associacao Brasileira de Medicina e Cirurgia do Tornozelo e Pe (ABTPe) ; 2020
    In:  Journal of the Foot & Ankle Vol. 14, No. 3 ( 2020-12-21), p. 301-308
    In: Journal of the Foot & Ankle, Associacao Brasileira de Medicina e Cirurgia do Tornozelo e Pe (ABTPe), Vol. 14, No. 3 ( 2020-12-21), p. 301-308
    Abstract: We present a technical surgical description of a 36-year-old female diagnosed with Progressive Collapsing Foot Deformity (PCFD) treated with a medial displacement calcaneus osteotomy, a lateral column lengthening, and a modified Lapidus fusion. In order to increase the plantar flexion power of this arthrodesis and minimize the loss in ray length with joint preparation, a bone block structured graft was used. Fixation was performed using a post implant in the medial cuneiform with crossing screws though the surfaces and the graft. Forefoot varus was properly corrected intraoperatively by using the described surgical technique. Satisfactory functional short-term results and an excellent alignment was accomplished. Level of Evidence V; Therapeutic Studies; Expert Opinion.
    Type of Medium: Online Resource
    ISSN: 2675-2980
    Language: Unknown
    Publisher: Associacao Brasileira de Medicina e Cirurgia do Tornozelo e Pe (ABTPe)
    Publication Date: 2020
    detail.hit.zdb_id: 3040308-X
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  • 7
    In: Foot & Ankle Orthopaedics, SAGE Publications, Vol. 7, No. 2 ( 2022-04), p. 2473011421S0053-
    Abstract: Hindfoot; Midfoot/Forefoot Introduction/Purpose: Posterior Tibial Tendon (PTT) dysfunction is considered to play an important role in Adult Acquired Flatfoot Deformity recently renamed Progressive Collapsing Foot Deformity (PCFD). Previous flatfoot classifications are mainly based on a progressive mechanical failure of the PTT causing chronological appearance of deformities. A consensus of experts recently met and decided to remove the central place of the PTT dysfunction from the PCFD classification system. The primary objective of our study was to assess the relation between the PTT clinical status and the three-dimensional overall foot deformity. The secondary objective was to assess the relation between the degeneration of PTT at the MRI and the three- dimensional overall foot deformity. We hypothesized that the more damaged the PTT, the more severe the deformity of the foot. Methods: We retrospectively identified all symptomatic PCFD over 18 years old who consulted our center from 01/01/2019 to 12/31/2020. PCFD with concomitant ( 〈 3 mois) clinical examination, Weight-Bearing CT (WBCT) and MRI were included. PCFD presenting with previous surgical intervention were excluded. Finally 25 PCFD were included in the analysis (19 Women, mean age 53.96+/-14.9 years, mean BMI 33.2+/-8.1 kg/m 2 ;)A PCFD presenting either a deficit on the single heel rise test or a decrease in inversion strength (superior or equal to 3/5) was classified PTT deficient. The MRI of all these PCFD were analyzed, and PTT degeneration was classified according to Deland and Rosenberg classifications. The three-dimensional overall deformity of each PCFD was assessed on WBCT by the Foot and Ankle Offset (FAO). Normality of different variables were assessed using Shapiro- Wilk test. Comparisons were performed using Student's t-test or Anova for normal, and Mann-Whitney or Kruskal-Wallis's test for non-normal variables. Results: Patients with clinically deficient PTT (13/25 PCFD, 52%) had a mean FAO of 7.75+/-3.8% whereas patients without PTT deficit (12/25 PCFD, 48%) had a mean FAO of 6.68+/-3.9%, without significant difference between groups (p=0.49). According to Deland classification, 4/25 PTT (16%) were classified grade 0, 7/25 (28%) grade 1, 4/25 (16%) grade 2, 5/25 (20%) grade 3 and 5/25 (20%) grade 4 without any significant difference between groups (p=0.36).According to Rosenberg classification, 4/25 PTT (16%) were classified type 0, 15/25 (60%) type 1, 2/25 (8%) type 2 and 4/25(16%) type 3 without any significant difference between groups (p=0.79).Seven PCFD had a FAO 〉 10%. Among them, 42.9% had a PTT without clinical deficit and 57.1% had a PTT with little or no damage on the MRI. Nine PCFD had a FAO 〈 5%. Among them, 44.4% had a PTT clinically deficient and 22.2% had a PTT with important damage on the MRI. Conclusion: The importance of three-dimensional overall foot deformity in PCFD was neither correlated with the clinical presence or absence of PTT deficiency, nor with the PTT degeneration on MRI in our study. A patient with important deformity may have an intact PTT and a patient with small deformity can present a deficient PTT. Despite the obvious lack of power in this study, it does not appear that PTT plays a significant role in the PCFD overall deformity.
    Type of Medium: Online Resource
    ISSN: 2473-0114 , 2473-0114
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2874570-X
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  • 8
    In: Journal of the Foot & Ankle, Associacao Brasileira de Medicina e Cirurgia do Tornozelo e Pe (ABTPe), Vol. 15, No. 2 ( 2021-08-31), p. 95-99
    Abstract: Objective: To assess the degree of implant-related artifacts (IRA) around metallic and bio-integrative (BI) cannulated screws using Hounsfield units (HU) on computed tomography (CT). Our hypothesis was that BI implants would demonstrate significantly decreased IRA around the inserted screws. Methods: In this cadaveric CT imaging study, we used 2 below-knee specimens. Medial displacement calcaneal osteotomy was performed, and the specimens were fixed with either metallic or BI screws. HU values were measured over 4 different lines that crossed the osteotomy position. Results: The mean HU value was decreased in the BI implants compared to the metallic ones in 3 different positions: near the screw, directly over the screw, and inside the screw cannula. At the line placed 1 cm dorsal to the screw, the HU value for the metallic screw was lower than that for the BI screw. Conclusions: We found metallic implants to demonstrate significantly increased HU values in regions close to the implant and significantly decreased values 1 cm away from the implant, when compared to the BI screw. The decreased HU values 1 cm away from the implant could be due to a shielding effect of the surrounding bone, hindering the assessment of union and healing. BI implants represent an alternative to decrease these IRA effects. Level of Evidence III; Case-Control Study.
    Type of Medium: Online Resource
    ISSN: 2675-2980
    Language: Unknown
    Publisher: Associacao Brasileira de Medicina e Cirurgia do Tornozelo e Pe (ABTPe)
    Publication Date: 2021
    detail.hit.zdb_id: 3040308-X
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  • 9
    In: Foot & Ankle Orthopaedics, SAGE Publications, Vol. 7, No. 1 ( 2022-01)
    Abstract: Midfoot/Forefoot Introduction/Purpose: Medial column instability (MCI) in Progressive Collapsing Foot Deformity (PCFD) is not solely determined by forefoot varus (FV). First ray hypermobility, hallux valgus, midfoot arthritis, gapping at the tarsometatarsal joint and dorsal metatarsal migration are findings associated with MCI. Acknowledgement of this instability requires inclusion of a procedure to the medial column in order to correct the forefoot varus, stabilize the ray and bring the foot to a plantigrade tripod position. Cotton opening wedge medial cuneiform osteotomy and Lapidus tarsometatarsal arthrodesis are procedures of choice in these scenarios. We have combined these 2 procedures into one called Lapicotton. The purpose of this study was to present the short-term outcomes of this technique.We hypothesized that Lapicotton will improve both clinical and radiological outcomes. Methods: We performed an IRB-approved retrospective study comprising 3 PCFDs having benefited from a Lapicotton procedure. Clinical outcomes were assessed with the European Foot and Ankle Society Score (EFAS), the Foot Function Index Score (FFI) and the Pain Catastrophizing Scale (PCS). Radiographic outcomes were assessed using weight-bearing computed tomography (WBCT) assessments. Middle Cuneiform Floor distance, Forefoot Arch Angle, Middle Facet uncoverage percentage, Talonavicular Coverage angle and the Foot and Ankle Offset (FAO) were measured. All these data were both preoperatively and postoperatively collected. Comparison between preoperative and postoperative results were done as described below. The Kruskal-Wallis H-test for independent groups was used to compare median values of the EFAS. The Wilcoxon signed-rank test for paired samples was used to compare preoperative and postoperative variables of FFI and PCS. For the radiographic measurements, normality was assessed using Shapiro-Wilk test. Comparisons were made using Student tests for normal variables and Mann-Whitney for non-normals. Results: This small series included 2 female and 1 male, with a mean age of 56 and a mean BMI of 31.8 kg/m 2 . Mean follow up was 2.9+/-0.2 (range from 2.7 to 3.1) months. 2 out of 3 patients simultaneously benefited of a Medial Calcaneal Displacement Osteotomy (MDCO 10mm) and a Lateral Column Lengthening (LCL 8mm). The wedge sizes used for the Lapicotton were 8 mm in all cases. Regarding clinical outcomes, EFAS (p=0.79) and FFI (p=0.99) did not showed any significant improvement whereas PCS were significantly improved (Δ=-5.67[-9.2–2.2];p=0.03). Regarding radiological outcomes, fusion was present in all the cases at the maximal follow-up. Middle cuneiform floor distance and Forefoot Arch Angle were significantly increase (respectively Δ=6.9;CI95%=[6.4;7.4] ;p 〈 0.01 and Δ=7.5;CI95%=[4.3;10.8]p 〈 0.05). Middle Facet uncoverage was significantly improved (Δ=- 28.8;CI95%=[-33.1;-24.5]p 〈 0.01). Statistical power of the serie did not allowed comparison regarding the Talonavicular Coverage Angle (Δ=-14;CI95%=[-24;-3.9]) and the FAO (Δ=-3.9;CI95%=[-10.7;2.9] ). Conclusion: The Lapicotton procedure showed encouraging outcomes with fusion in all cases at 3 months postoperatively, improvement in pain, correction of forefoot varus and of the of the Peritalar subluxation represented by the Middle Facet Uncoverage. These results should be moderate because other procedures (MDCO and LCL) were performed in 2/3 of the patients, and the outcomes were issued from a small cohort with short-term follow-up. Longer follow-up and a larger cohort are needed to confirm these results.
    Type of Medium: Online Resource
    ISSN: 2473-0114 , 2473-0114
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2874570-X
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  • 10
    In: Foot & Ankle Orthopaedics, SAGE Publications, Vol. 7, No. 1 ( 2022-01)
    Abstract: Ankle Introduction/Purpose: Recently, weightbearing computed tomography (WBCT) has been utilized to provide more comprehensive and accurate assessment of complex foot and ankle deformities, notably to diagnose and stage Progressive Collapsing Foot Deformity (PCFD). The 3D data provided by WBCT has enabled the developed of novel tools like distance mapping (DM), coverage mapping (CM), and volume measurements. Over the past year, novel DM and CM have shown promise in providing sensitive automated measures of peritalar subluxation, a major component of PCFD. However, the early effects of PCFD on the tibiotalar joint have not yet been quantified. This study sought to use DM and CM to objectively characterize the effects of PCFD on the tibiotalar and tibiofibular joints. We hypothesized that changes seen in early PCFD will be identified. Methods: IRB approval for retrospective review of patient data from 2014-2020 was obtained to identify patients with clinical and radiographic diagnoses of PCFD. The first consecutive 20 patients with symptomatic flexible PCFD and high-resolution weightbearing CT examination without arthritis that had not undergone prior surgery were selected and compared with 20 controls. Fully automated volume measurements of the syndesmosis at 1cm, 3cm, and 5cm from the tibiotalar joint were performed as well as of the medial and lateral tibiotalar gutters based on models created in Disior Bonelogic. Distance Maps (DMs) were obtained for the tibiofibular incisura, tibiotalar joint, and gutters. Coverage maps (CMs) were created using the measured 3DDMs to identify joint interaction, subluxation, and impingement. Data were checked for normality using the Shapiro- Wilk W test. Two-tailed independent samples student t-tests or Wilcoxon Tests were used to assess differences between groups. Results: There were significant decreases in coverage of all 3 anterior regions of the tibiotalar joint in PCFD patients when compared to controls along with corresponding significant increases in coverage of all 3 posterior regions (Figure). There were no significant differences in mean or minimum distances in any region of the tibiotalar joint surface. Significant increases in average and minimum DMs of the anterior medial (36%, p 〈 0.01, 19%, p 〈 0.03) gutter were observed with significant decreases in coverage of both anterior medial and anterior lateral regions. Significant decreases in the average and minimum distances of the tibiofibular joint were found anteriorly in PCFD patients compared to controls (-26%, p 〈 0.006). There were no significant differences in overall syndesmotic distance or volume at any level. Conclusion: The results of our study were able to identify that, compared to controls, patients with early stage PCFD demonstrated significant tibiotalar and tibiofibular joint changes ahead of developing the tibiotalar narrowing associated with arthritis and syndesmotic widening associated with instability. Decreases in anterior coverage with increases posteriorly support early plantarflexion of the talus in PCFD. When combined with plantarflexion of the talus and unchanged syndesmotic volume, decreases in anterior tibiofibular distances support the absence of syndesmotic joint instability in early PCFD. Novel tools may assist with clinical decision-making regarding restoration of normal tibiotalar and tibiofibular alignment during PCFD correction.
    Type of Medium: Online Resource
    ISSN: 2473-0114 , 2473-0114
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2874570-X
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