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  • 1
    Online Resource
    Online Resource
    FapUNIFESP (SciELO) ; 2012
    In:  Fisioterapia em Movimento Vol. 25, No. 2 ( 2012-06), p. 435-443
    In: Fisioterapia em Movimento, FapUNIFESP (SciELO), Vol. 25, No. 2 ( 2012-06), p. 435-443
    Abstract: INTRODUCTION: Fragility syndrome, very common in elderly people, consists of a set of signals and symptoms in which is present criteria such as not intentional weight loss (approximately 5%) in a year, reduction in the walking speed, low physical activity levels, subjective exhaustion and muscular strength reduction. The increasing effect of these changes related to age, which include sarcopenia, immunity functional disorder and neuroendocrinous misconduct, increase the vulnerability of the organism to stress, reducing the ability to adapt, compensate or modulate these stimuli. Several intervention proposals have been made to attenuate this process, and resistance exercises (RE) was one of the options studied. OBJECTIVES: To evaluate the effects of RE on the physiopathology of fragility syndrome. MATERIALS AND METHODS: A bibliographic review of the period 2004-2010 was made based on the data of LILACS, MEDLINE and PubMed. Results: Changes in the hormonal and immune systems were observed acting in a systemic way by reverting or minimizing the effects of sarcopenia. CONCLUSION: Resistance exercises should serve as therapy to those elderly who are fragile and do not present any health problems.
    Type of Medium: Online Resource
    ISSN: 0103-5150
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2012
    detail.hit.zdb_id: 2630904-X
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  • 2
    In: Trials, Springer Science and Business Media LLC, Vol. 21, No. 1 ( 2020-12)
    Abstract: Chronic venous insufficiency (CVI) causes pathophysiological changes in the lower-limb muscles, particularly the calf muscles, and limits ankle range of motion (ROM). These changes reduce functional activities and decrease quality of life (QOL). Although several studies have shown the benefits of exercise (strengthening the calf muscles to improve calf-muscle pumping and QOL) in patients with CVI, few studies are randomized controlled trials. This has led to a weak indication of exercise for the treatment of patients with CVI. The aim of this study is to analyze the effects of a supervised exercise program to improve calf-muscle endurance as well as QOL in patients with CVI. Methods/design This is an evaluator-blind, randomized clinical trial with an 8-week duration and a follow-up evaluation at week 16. A pilot study with subjects with a CVI diagnosis will be performed to calculate sample size. The participants will be randomly allocated (1:1) into a treatment or a control group (usual care/no intervention). The treatment intervention consists of a bi-weekly supervised exercise program of the lower limbs that will include aerobic training, strengthening and cardiovascular exercises. The participants from both groups will participate in a health education lecture. Primary outcomes are changes in calf-muscle endurance and QOL score. Secondary outcomes are changes in exercise capacity, ankle ROM, electrical muscle activity and cardiac output. The first statistical comparison will be performed after 8 weeks’ intervention. Discussion Patients with CVI may have an impaired calf-muscle pump and decreased exercise capacity. A randomized controlled trial evaluating a supervised exercise program should provide much needed information on the management of CVI to promote health and independence. Trial registration This study was registered on the Brazilian Clinical Trials Database (REBEC) ( RBR-57xtk7 ). The results will be disseminated at scientific events, presentations, and publications in peer-reviewed journals.
    Type of Medium: Online Resource
    ISSN: 1745-6215
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2020
    detail.hit.zdb_id: 2040523-6
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