In:
European Heart Journal - Cardiovascular Pharmacotherapy, Oxford University Press (OUP), Vol. 6, No. 2 ( 2020-03-01), p. 97-103
Abstract:
Randomized clinical trials (RCTs) are important and the Gold Standard for drugs in modern cardiovascular (CV) therapy. The cornerstone of RCTs is the recording of hard clinical endpoints instead of surrogates. It is important to select an appropriate endpoint. Efficacy endpoints must be clinically relevant and can be hierarchically divided. A very interesting innovation in endpoint acquisition is the total event paradigm.
Type of Medium:
Online Resource
ISSN:
2055-6837
,
2055-6845
DOI:
10.1093/ehjcvp/pvz029
Language:
English
Publisher:
Oxford University Press (OUP)
Publication Date:
2020
detail.hit.zdb_id:
2808613-2
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