In:
Advanced Materials, Wiley, Vol. 34, No. 19 ( 2022-05)
Abstract:
Materials with long‐wavelength second near‐infrared (NIR‐II) emission are highly desired for in vivo dynamic visualizating of microstructures in deep tissues. Herein, by employing an atom‐programming strategy, a series of highly fluorescent semiconducting oligomers (SOMs) with tunable NIR‐IIb emissions are developed for bioimaging applications. After self‐assembly into nanoparticles (NPs), they show good brightness, high photostability, and satisfactory biocompatibility. The SOM NPs are applied as probes for high‐resolution imaging of whole‐body and hind‐limb blood vessels, biliary tract, and bladder with their emissions over 1500 nm. This work demonstrates an atom‐programming strategy for constructing semiconducting small molecules with enhanced NIR‐II fluorescence for deep‐tissue imaging, affording new insight for advancing molecular design of NIR‐II fluorophores.
Type of Medium:
Online Resource
ISSN:
0935-9648
,
1521-4095
DOI:
10.1002/adma.202201263
Language:
English
Publisher:
Wiley
Publication Date:
2022
detail.hit.zdb_id:
1474949-X
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