In:
PLOS ONE, Public Library of Science (PLoS), Vol. 16, No. 3 ( 2021-3-25), p. e0249194-
Abstract:
The Barcelona Clinic Liver Cancer (BCLC) staging system is the most widely applied staging system for hepatocellular carcinoma (HCC) and is recommended for treatment allocation and prognostic prediction. The BCLC guidelines were modified in 2018 to indicate that Child-Pugh A without any ascites is essential for all stages except stage D. This study sought to provide a description of patients with HCC treated at a high-volume liver surgery center in Taiwan where referral is not needed and all treatment modalities are available and reimbursed by the National Health Insurance program. As such, certain variables that could modulate treatment decisions in clinical practice, including financial constraints, the availability of treatment procedures, and the expertise of the hospital, could be excluded. The study further sought to evaluate the adherence to the modified BCLC guidelines. Methods This was a retrospective study with prospectively collected data. 1801 consecutive patients with de novo HCC were enrolled through our institution from 2011–2017. Results There were 302 patients with stage 0, 783 with stage A, 242 with stage B, 358 with stage C, and 116 with stage D HCC. Treatment adhering to the modified BCLC guidelines recommendations was provided to 259 (85.8%) stage 0 patients, 606 (77.4%) stage A patients, 120 (49.6%) stage B patients, 93 (26.0%) stage C patients, and 83 (71.6%) stage D patients. Conclusions We reported treatment adhering to the modified BCLC guidelines at a high-volume liver surgery center in Taiwan. We found that non-adherence to the modified BCLC staging system was common in treating stage B and C patients.
Type of Medium:
Online Resource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0249194
DOI:
10.1371/journal.pone.0249194.g001
DOI:
10.1371/journal.pone.0249194.g002
DOI:
10.1371/journal.pone.0249194.g003
DOI:
10.1371/journal.pone.0249194.t001
DOI:
10.1371/journal.pone.0249194.t002
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10.1371/journal.pone.0249194.t003
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10.1371/journal.pone.0249194.t004
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10.1371/journal.pone.0249194.t005
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10.1371/journal.pone.0249194.t006
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10.1371/journal.pone.0249194.t007
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10.1371/journal.pone.0249194.t008
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10.1371/journal.pone.0249194.t009
DOI:
10.1371/journal.pone.0249194.t010
DOI:
10.1371/journal.pone.0249194.t011
DOI:
10.1371/journal.pone.0249194.t012
DOI:
10.1371/journal.pone.0249194.s001
DOI:
10.1371/journal.pone.0249194.r001
DOI:
10.1371/journal.pone.0249194.r002
DOI:
10.1371/journal.pone.0249194.r003
DOI:
10.1371/journal.pone.0249194.r004
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2021
detail.hit.zdb_id:
2267670-3
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