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Universal artificial intelligence platform for collaborative management of cataracts

Wu, Xiaohang ; Huang, Yelin ; Liu, Zhenzhen ; [et al.]

BMJ ; 2019

In: British Journal of Ophthalmology Vol. 103, No. 11 ( 2019-11), p. 1553-1560

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In: British Journal of Ophthalmology, BMJ, Vol. 103, No. 11 ( 2019-11), p. 1553-1560

Abstract: To establish and validate a universal artificial intelligence (AI) platform for collaborative management of cataracts involving multilevel clinical scenarios and explored an AI-based medical referral pattern to improve collaborative efficiency and resource coverage. Methods The training and validation datasets were derived from the Chinese Medical Alliance for Artificial Intelligence, covering multilevel healthcare facilities and capture modes. The datasets were labelled using a three-step strategy: (1) capture mode recognition; (2) cataract diagnosis as a normal lens, cataract or a postoperative eye and (3) detection of referable cataracts with respect to aetiology and severity. Moreover, we integrated the cataract AI agent with a real-world multilevel referral pattern involving self-monitoring at home, primary healthcare and specialised hospital services. Results The universal AI platform and multilevel collaborative pattern showed robust diagnostic performance in three-step tasks: (1) capture mode recognition (area under the curve (AUC) 99.28%–99.71%), (2) cataract diagnosis (normal lens, cataract or postoperative eye with AUCs of 99.82%, 99.96% and 99.93% for mydriatic-slit lamp mode and AUCs 〉 99% for other capture modes) and (3) detection of referable cataracts (AUCs 〉 91% in all tests). In the real-world tertiary referral pattern, the agent suggested 30.3% of people be ‘referred’, substantially increasing the ophthalmologist-to-population service ratio by 10.2-fold compared with the traditional pattern. Conclusions The universal AI platform and multilevel collaborative pattern showed robust diagnostic performance and effective service for cataracts. The context of our AI-based medical referral pattern will be extended to other common disease conditions and resource-intensive situations.

Type of Medium: Online Resource

ISSN: 0007-1161 , 1468-2079

URL: Article

DOI: 10.1136/bjophthalmol-2019-314729

RVK:

XA 10000

Language: English

Publisher: BMJ

Publication Date: 2019

detail.hit.zdb_id: 1482974-5

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A universal artificial intelligence platform for collaborative management of cataracts

Wu, Xiaohang ; Huang, Yelin ; Liu, Zhenzhen ; [et al.]

Elsevier BV ; 2019

In: The Lancet Vol. 394 ( 2019-10), p. S22-

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In: The Lancet, Elsevier BV, Vol. 394 ( 2019-10), p. S22-

Type of Medium: Online Resource

ISSN: 0140-6736

URL: Article

DOI: 10.1016/S0140-6736(19)32358-X

RVK:

XA 10000

Language: English

Publisher: Elsevier BV

Publication Date: 2019

detail.hit.zdb_id: 2067452-1

detail.hit.zdb_id: 3306-6

detail.hit.zdb_id: 1476593-7

SSG: 5,21

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Trait evaluation and trial cultivation of Dongfang No. 2, the hybrid of a male gametophyte clone of Laminaria longissima (Laminariales, Phaeophyta) and a female one of L. japonica

Li, Xiaojie ; Cong, Yizhou ; Yang, Guanpin ; [et al.]

Springer Science and Business Media LLC ; 2007

In: Journal of Applied Phycology Vol. 19, No. 2 ( 2007-3-27), p. 139-151

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In: Journal of Applied Phycology, Springer Science and Business Media LLC, Vol. 19, No. 2 ( 2007-3-27), p. 139-151

Type of Medium: Online Resource

ISSN: 0921-8971 , 1573-5176

URL: Article

DOI: 10.1007/s10811-006-9120-0

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2007

detail.hit.zdb_id: 1002324-0

detail.hit.zdb_id: 1477703-4

SSG: 12

SSG: 14

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Targeting Adults for Supplementary Immunization Activities of Measles Control in Central China: A Mathematical Modelling Study

Chong, Ka Chun ; Zhang, Chi ; Jia, Katherine Min ; [et al.]

Springer Science and Business Media LLC ; 2018

In: Scientific Reports Vol. 8, No. 1 ( 2018-10-31)

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In: Scientific Reports, Springer Science and Business Media LLC, Vol. 8, No. 1 ( 2018-10-31)

Abstract: Routine immunizations and supplementary immunization activities (SIAs) have significantly improved measles control over the past two decades in China. Progress towards eliminating measles currently faces multiple challenges as the infection age increases, and adult-targeted SIA strategies are being considered. This study developed an age-stratified susceptible-exposed-infectious-recovered model using a recently published contact matrix to depict measles transmissions between individuals in seven age groups. Hubei, a high measles-incidence province in central China, was the selected setting. The baseline scenario was calibrated by fitting with the 2012–2015 age-stratified incidence data. SIAs targeting multiple age groups were simulated. Adult-targeted ( 〉 29 years) two-year SIA cycles produced the greatest annual incidence rate decrease, reducing incidences by half over a long timespan with 90% coverage levels. Incidences could remain below 10/100,000 until 2030 if SIAs were provided to individuals ≥6 years old with at least 50% coverage. These findings will help officials prioritize supplementary vaccination strategies. Public health officials in China should consider adult-to-adult transmissions and provide adult-targeted SIAs. Although officials have reported approximately 90% SIA coverage in the past, SIAs for the adult population should be provided on shorter intervals, particularly for the aging population with decreased immunity.

Type of Medium: Online Resource

ISSN: 2045-2322

URL: Article

DOI: 10.1038/s41598-018-34461-0

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2018

detail.hit.zdb_id: 2615211-3

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A Universal Artificial Intelligence Platform for Collaborative Management of Cataracts

Wu, Xiaohang ; Liu, Zhenzhen ; Lai, Weiyi ; [et al.]

Elsevier BV ; 2019

In: SSRN Electronic Journal

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In: SSRN Electronic Journal, Elsevier BV

Type of Medium: Online Resource

ISSN: 1556-5068

URL: Article

DOI: 10.2139/ssrn.3352014

Language: English

Publisher: Elsevier BV

Publication Date: 2019

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Interpreting the transmissibility of measles in two different post periods of supplementary immunization activities in Hubei, China

Chong, Ka Chun ; Zhang, Chi ; Zee, Benny Chung Ying ; [et al.]

Elsevier BV ; 2017

In: Vaccine Vol. 35, No. 7 ( 2017-02), p. 1024-1029

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In: Vaccine, Elsevier BV, Vol. 35, No. 7 ( 2017-02), p. 1024-1029

Type of Medium: Online Resource

ISSN: 0264-410X

URL: Article

DOI: 10.1016/j.vaccine.2017.01.010

Language: English

Publisher: Elsevier BV

Publication Date: 2017

detail.hit.zdb_id: 1468474-3

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Prediction of myopia development among Chinese school-aged children using refraction data from electronic medical records: A retrospective, multicentre machine learning study

Lin, Haotian ; Long, Erping ; Ding, Xiaohu ; [et al.]

Public Library of Science (PLoS) ; 2018

In: PLOS Medicine Vol. 15, No. 11 ( 2018-11-6), p. e1002674-

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In: PLOS Medicine, Public Library of Science (PLoS), Vol. 15, No. 11 ( 2018-11-6), p. e1002674-

Type of Medium: Online Resource

ISSN: 1549-1676

URL: Article

DOI: 10.1371/journal.pmed.1002674

DOI: 10.1371/journal.pmed.1002674.g001

DOI: 10.1371/journal.pmed.1002674.g002

DOI: 10.1371/journal.pmed.1002674.g003

DOI: 10.1371/journal.pmed.1002674.g004

DOI: 10.1371/journal.pmed.1002674.g005

DOI: 10.1371/journal.pmed.1002674.t001

DOI: 10.1371/journal.pmed.1002674.t002

DOI: 10.1371/journal.pmed.1002674.t003

DOI: 10.1371/journal.pmed.1002674.s001

DOI: 10.1371/journal.pmed.1002674.s002

DOI: 10.1371/journal.pmed.1002674.s003

DOI: 10.1371/journal.pmed.1002674.s004

DOI: 10.1371/journal.pmed.1002674.s005

DOI: 10.1371/journal.pmed.1002674.s006

DOI: 10.1371/journal.pmed.1002674.s007

DOI: 10.1371/journal.pmed.1002674.s008

DOI: 10.1371/journal.pmed.1002674.s009

Language: English

Publisher: Public Library of Science (PLoS)

Publication Date: 2018

detail.hit.zdb_id: 2164823-2

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Clinical characteristics of young adult cataract patients: a 10-year retrospective study of the Zhongshan Ophthalmic Center

Lin, Duoru ; Liu, Zhenzhen ; Cao, Qianzhong ; [et al.]

BMJ ; 2018

In: BMJ Open Vol. 8, No. 7 ( 2018-07), p. e020234-

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In: BMJ Open, BMJ, Vol. 8, No. 7 ( 2018-07), p. e020234-

Abstract: To investigate the characteristics of young adult cataract (YAC) patients over a 10-year period. Methods This observational study included YAC patients aged 18–49 years who were treated surgically for the first time at the Zhongshan Ophthalmic Center in China. YAC patients were analysed and compared with patients with childhood cataract (CC) in January 2005 to December 2014. Results During the 10-year period, 515 YAC patients and 2421 inpatients with CC were enrolled. Among the YAC patients, 76.76% (109/142) of unilateral patients had a corrected distance visual acuity (CDVA) better than 20/40 in the healthy eye, whereas only 20.38% (76/373) of bilateral patients had a CDVA better than 20/40 in the eye with better visual acuity. Compared with the CC group, the YAC group had a higher proportion of rural patients (40.40% vs 31.60%, p=0.001). Furthermore, the prevalence of other ocular abnormalities in YAC patients was higher than that in patients with CC (29.71% vs 17.47%, p 〈 0.001). Conclusions A large proportion coming from rural areas and a high prevalence of complicated ocular abnormalities may be the most salient characteristics of YAC patients. Strengthening the counselling and screening strategy for cataract and health education for young adults are required especially for those in rural areas.

Type of Medium: Online Resource

ISSN: 2044-6055 , 2044-6055

URL: Article

DOI: 10.1136/bmjopen-2017-020234

Language: English

Publisher: BMJ

Publication Date: 2018

detail.hit.zdb_id: 2599832-8

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Construction and implications of structural equation modeling network for pediatric cataract: a data mining research of rare diseases

Long, Erping ; Xu, Shuangjuan ; Liu, Zhenzhen ; [et al.]

Springer Science and Business Media LLC ; 2017

In: BMC Ophthalmology Vol. 17, No. 1 ( 2017-12)

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In: BMC Ophthalmology, Springer Science and Business Media LLC, Vol. 17, No. 1 ( 2017-12)

Type of Medium: Online Resource

ISSN: 1471-2415

URL: Article

DOI: 10.1186/s12886-017-0468-5

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2017

detail.hit.zdb_id: 2050436-6

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The epidemiology and etiology of influenza-like illness in Chinese children from 2008 to 2010

Peng, Jinsong ; Kong, Wenhua ; Guo, Deyin ; [et al.]

Wiley ; 2012

In: Journal of Medical Virology Vol. 84, No. 4 ( 2012-04), p. 672-678

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In: Journal of Medical Virology, Wiley, Vol. 84, No. 4 ( 2012-04), p. 672-678

Type of Medium: Online Resource

ISSN: 0146-6615

URL: Issue

URL: Article

DOI: 10.1002/jmv.v84.4

DOI: 10.1002/jmv.22247

RVK:

XA 10000

Language: English

Publisher: Wiley

Publication Date: 2012

detail.hit.zdb_id: 752392-0

detail.hit.zdb_id: 1475090-9

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