In:
Molecular Oncology, Wiley, Vol. 9, No. 6 ( 2015-06), p. 1106-1119
Abstract:
A combination of in vitro findings and breast cancer patient data analysis uncovers the mechanism of gene regulation by miR‐30c‐2‐3p. miR‐30c‐2‐3p expression is lower in the ER negative subtypes, which are associated with active NF‐κB signaling and a more aggressive physiology. miR‐30c‐2‐3p directly targets TRADD and CCNE1, leading to reduced cytokine expression, cell invasion, as well as cell proliferation in vitro.
Type of Medium:
Online Resource
ISSN:
1574-7891
,
1878-0261
DOI:
10.1016/j.molonc.2015.01.008
Language:
English
Publisher:
Wiley
Publication Date:
2015
detail.hit.zdb_id:
2322586-5
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