In:
Geriatrics & Gerontology International, Wiley, Vol. 15, No. 6 ( 2015-06), p. 707-714
Abstract:
Personal mastery has been associated with physical function maintenance later in life. Less is known about the relationship between lack of personal mastery and functional decline in A sian populations, and whether multisystem physiological dysregulation explains this relationship. Methods Participants ( n = 487) from the S ocial E nvironment and B iomarkers of A ging S tudy, a population‐based prospective cohort study in T aiwan, received baseline measurements of personal mastery using the P earlin M astery S cale. Multisystem physiological dysregulation at baseline was assessed as a summary score based on the levels of 16 biomarkers of the hypothalamic–pituitary–adrenal axis, the sympathetic nervous system, the cardiovascular system, the metabolic system and the immune system functioning. Function in activities of daily living was determined at baseline and at a 7‐year follow up. Results Participants in the lowest quartile of the personal mastery score were more likely to experience functional decline than those in the higher quartiles ( OR comparing the lowest with highest 3 quartiles 2.99, 95% CI 1.71–5.21). After adjusting for confounders, personal mastery remained significantly associated with functional changes (adjusted OR 2.09, 95% CI 1.05–4.14). Greater sense of personal mastery was associated with significantly less multisystem physiological dysregulation ( P for trend = 0.001). When the levels of physiological dysregulation were added to the multivariate models, the association between a poor sense of personal mastery and functional decline was attenuated. Conclusions Lack of personal mastery is independently associated with an increased risk of functional decline in older adults. Multisystem physiological dysregulation partially explains this relationship. Geriatr Gerontol Int 2015; 15: 707–714.
Type of Medium:
Online Resource
ISSN:
1444-1586
,
1447-0594
DOI:
10.1111/ggi.2015.15.issue-6
Language:
English
Publisher:
Wiley
Publication Date:
2015
detail.hit.zdb_id:
2078308-5
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