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  • 1
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    Online Resource
    A robust and automatic CT‐3D ultrasound registration method based on segmentation, context, and edge hybrid metric
    Wiley ; 2023
    In:  Medical Physics
    Details
    In: Medical Physics, Wiley
    Abstract: The fusion of computed tomography (CT) and ultrasound (US) image can enhance lesion detection ability and improve the success rate of liver interventional radiology. The image‐based fusion methods encounter the challenge of registration initialization due to the random scanning pose and limited field of view of US. Existing automatic methods those used vessel geometric information and intensity‐based metric are sensitive to parameters and have low success rate. The learning‐based methods require a large number of registered datasets for training. Purpose The aim of this study is to provide a fully automatic and robust US‐3D CT registration method without registered training data and user‐specified parameters assisted by the revolutionary deep learning‐based segmentation, which can further be used for preparing training samples for the study of learning‐based methods. Methods We propose a fully automatic CT‐3D US registration method by two improved registration metrics. We propose to use 3D U‐Net‐based multi‐organ segmentation of US and CT to assist the conventional registration. The rigid transform is searched in the space of any paired vessel bifurcation planes where the best transform is decided by a segmentation overlap metric, which is more related to the segmentation precision than Dice coefficient. In nonrigid registration phase, we propose a hybrid context and edge based image similarity metric with a simple mask that can remove most noisy US voxels to guide the B‐spline transform registration. We evaluate our method on 42 paired CT‐3D US datasets scanned with two different US devices from two hospitals. We compared our methods with other exsiting methods with both quantitative measures of target registration error (TRE) and the Jacobian determinent with paired t ‐test and qualitative registration imaging results. Results The results show that our method achieves fully automatic rigid registration TRE of 4.895 mm, deformable registration TRE of 2.995 mm in average, which outperforms state‐of‐the‐art automatic linear methods and nonlinear registration metrics with paired t ‐test's p value less than 0.05. The proposed overlap metric achieves better results than self similarity description (SSD), edge matching (EM), and block matching (BM) with p values of 1.624E‐10, 4.235E‐9, and 0.002, respectively. The proposed hybrid edge and context‐based metric outperforms context‐only, edge‐only, and intensity statistics‐only‐based metrics with p values of 0.023, 3.81E‐5, and 1.38E‐15, respectively. The 3D US segmentation has achieved mean Dice similarity coefficient (DSC) of 0.799, 0.724, 0.788, and precision of 0.871, 0.769, 0.862 for gallbladder, vessel, and branch vessel, respectively. Conclusions The deep learning‐based US segmentation can achieve satisfied result to assist robust conventional rigid registration. The Dice similarity coefficient‐based metrics, hybrid context, and edge image similarity metric contribute to robust and accurate registration.
    Type of Medium: Online Resource
    ISSN: 0094-2405 , 2473-4209
    URL: Article
    DOI: 10.1002/mp.16396
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 1466421-5
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  • 2
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    Laparoscopic common bile duct exploration with primary closure could be safely performed among elderly patients with choledocholithiasis
    Springer Science and Business Media LLC ; 2023
    In:  BMC Geriatrics Vol. 23, No. 1 ( 2023-08-11)
    Details
    In: BMC Geriatrics, Springer Science and Business Media LLC, Vol. 23, No. 1 ( 2023-08-11)
    Abstract: For patients with choledocholithiasis, laparoscopic common bile duct exploration (LCBDE) is preferred over open surgery. Whether primary closure of the common bile duct (CBD) should be performed upon completion of choledochotomy remains unclear, and the corresponding indications for primary closure of the common bile duct have yet to be fully identified. This study was performed to evaluate the safety and feasibility of primary closure of CBD among elderly patients (≥ 70 years) after LCBDE. Methods Patients with choledocholithiasis who had undergone LCBDE with primary closure of the CBD between July 2014 and December 2020 were retrospectively reviewed. Included patients were assigned into two groups (Group A: ≥70 years and Group B: 〈 70 years) according to age. Group A was compared with Group B in terms of preoperative characteristics, intraoperative results and postoperative outcomes. Results The mean operative time for Group A was 176.59 min (± 68.950), while the mean operative time for Group B was 167.64 min (± 69.635) (P = 0.324). The mean hospital stay after surgery for Group A was 8.43 days (± 4.440), while that for Group B was 8.30 days (± 5.203) (P = 0.849). Three patients in Group A experienced bile leakage, while bile leakage occurred in 10 patients in Group B (3.8% vs. 4.5%, P = 0.781). Group A was not significantly different from Group B in terms of postoperative complications and 30-day mortality except pneumonia (P = 0.016), acute cardiovascular event (P = 0.005) and ICU observation (P = 0.037). After a median follow-up time of 60 months, 2 patients in Group A and 2 patients in Group B experienced stone recurrence (2.5% vs. 0.9%, P = 0.612). One patient in Group A experienced stenosis of the CBD, while stenosis of the CBD occurred in 5 patients in Group B (1.3% vs. 2.2%, P = 0.937). Conclusions Primary closure of CBD upon completion of LCBDE could be safely performed among patients ≥ 70 years.
    Type of Medium: Online Resource
    ISSN: 1471-2318
    URL: Article
    DOI: 10.1186/s12877-023-04149-w
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 2059865-8
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  • 3
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    Acoustic topological valley transport with multimode edge states
    AIP Publishing ; 2021
    In:  Journal of Applied Physics Vol. 130, No. 12 ( 2021-09-28)
    Details
    In: Journal of Applied Physics, AIP Publishing, Vol. 130, No. 12 ( 2021-09-28)
    Abstract: Acoustic transport through topological edge states in phononic crystals improves the suppression of backscattering, which gives these systems significant potential for controlling sound waves. Recent research shows that only one acoustic edge state caused by topological valley phases can transmit in phononic crystals. This paper proposes a genre of valley phases with one, two, and three topological edge states created by transforming the structure of unit cells. The bulk-edge correspondence indicates that these edge states are topological based on the topological invariant number (i.e., the valley Chern number of one, two, and three) of this system coinciding with the number of topological edge states. Different types of defects are introduced into the phononic crystals, whose transmission spectra show that they can withstand bending defects. These results indicate that these systems have significant potential for application in noise control, acoustic communication, and acoustic-electrical integration.
    Type of Medium: Online Resource
    ISSN: 0021-8979 , 1089-7550
    URL: Article
    DOI: 10.1063/5.0058715
    Language: English
    Publisher: AIP Publishing
    Publication Date: 2021
    detail.hit.zdb_id: 220641-9
    detail.hit.zdb_id: 3112-4
    detail.hit.zdb_id: 1476463-5
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  • 4
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    Does the level of inferior mesenteric artery ligation affect short-term and long-term outcomes of patients with sigmoid colon cancer or rectal cancer? A single-center retrospective study
    Springer Science and Business Media LLC ; 2022
    In:  World Journal of Surgical Oncology Vol. 20, No. 1 ( 2022-09-01)
    Details
    In: World Journal of Surgical Oncology, Springer Science and Business Media LLC, Vol. 20, No. 1 ( 2022-09-01)
    Abstract: For sigmoid colon or rectal cancer, a definite consensus regarding the optimal level ligating the inferior mesenteric artery (IMA) has not been reached. We performed this study to determine whether the ligation level significantly affected short-term and long-term outcomes of patients with sigmoid colon or rectal cancer after curative laparoscopic surgery. Methods Medical records of patients with sigmoid colon or rectal cancer who had undergone curative laparoscopic surgery between January 2008 and December 2014 at the Department of Gastrointestinal Surgery, Guangdong Provincial Hospital of Traditional Chinese Medicine were reviewed. Then, the high tie group (HTG) was compared with the low tie group (LTG) in terms of short-term and long-term outcomes. Results Five-hundred ninety patients were included. No significant differences between two groups regarding baseline characteristics existed. HTG had a significantly higher risk of anastomotic fistula than LTG (21/283 vs 11/307, P = 0.040). Additionally, high ligation was proven by multivariate logistic regression analysis to be an independent factor for anastomotic fistula ( P = 0.038, OR = 2.232, 95% CI : 1.047–4.758). Furthermore, LT resulted in better preserved urinary function. However, LTG was not significantly different from HTG regarding operative time ( P = 0.075), blood transfusion ( P = 1.000), estimated blood loss ( P = 0.239), 30-day mortality ( P = 1.000), ICU stay ( P = 0.674), postoperative hospital stay (days) ( P = 0.636), bowel obstruction ( P = 0.659), ileus ( P = 0.637), surgical site infection (SSI) ( P = 0.121), number of retrieved lymph nodes ( P = 0.501), and number of metastatic lymph nodes ( P = 0.131). Subsequently, it was revealed that level of IMA ligation did not significantly influence overall survival (OS) ( P = 0.474) and relapse-free survival (RFS) ( P = 0.722). Additionally, it was revealed that ligation level did not significantly affect OS ( P = 0.460) and RFS ( P = 0.979) of patients with stage 1 cancer, which was also observed among patients with stage 2 or stage 3 cancer. Ultimately, ligation level was not an independent predictive factor for either OS or RFS. Conclusions HT resulted in a significantly higher incidence of anastomotic fistula and worse preservation of urinary function. Level of IMA ligation did not significantly affect long-term outcomes of patients with sigmoid colon or rectal cancer after curative laparoscopic surgery.
    Type of Medium: Online Resource
    ISSN: 1477-7819
    URL: Article
    DOI: 10.1186/s12957-022-02741-9
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 2118383-1
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  • 5
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    Extracellular vesicles‐derived miR‐150‐5p secreted by adipose‐derived mesenchymal stem cells inhibits CXCL1 expression to attenuate hepatic fibrosis
    Wiley ; 2021
    In:  Journal of Cellular and Molecular Medicine Vol. 25, No. 2 ( 2021-01), p. 701-715
    Details
    In: Journal of Cellular and Molecular Medicine, Wiley, Vol. 25, No. 2 ( 2021-01), p. 701-715
    Abstract: Hepatic fibrosis (HF) is involved in aggravated wound‐healing response as chronic liver injury. Extracellular vesicles (EVs) carrying microRNA (miR) have been reported as therapeutic targets for liver diseases. In this study, we set out to explore whether adipose‐derived mesenchymal stem cells (ADMSCs)‐derived EVs containing miR‐150‐5p affect the progression of HF. Carbon tetrachloride (CCl 4 ) was firstly used to induce HF mouse models in C57BL/6J mice, and activation of hepatic stellate cells (HSCs) was achieved using transforming growth factor β (TGF‐β). EVs were then isolated from ADMSCs and co‐cultured with HSCs. The relationship between miR‐150‐5p and CXCL1 was identified using dual luciferase gene reporter assay. Following loss‐ and gain‐function experimentation, HSC proliferation was examined by MTT assay, and levels of fibrosis‐, HSC activation‐ and apoptosis‐related genes were determined in vitro. Additionally, pathological scores, collagen volume fraction ( CVF) as well as levels of inflammation‐ and hepatic injury‐associated genes were determined in in vivo. Down‐regulated miR‐150‐5p and elevated CXCL1 expression levels were detected in HF tissues. ADMSCs‐derived EVs transferred miR‐150‐5p to HSCs. CXCL1 was further verified as the downstream target gene of miR‐150‐5p. Moreover, ADMSCs‐EVs containing miR‐150‐5p markedly inhibited HSC proliferation and activation in vitro. Meanwhile, in vivo experiments also concurred with the aforementioned results as demonstrated by inhibited CVF, reduced inflammatory factor levels and hepatic injury‐associated indicators. Both experiments results were could be reversed by CXCL1 over‐expression. Collectively, our findings indicate that ADMSCs‐derived EVs containing miR‐150‐5p attenuate HF by inhibiting the CXCL1 expression.
    Type of Medium: Online Resource
    ISSN: 1582-1838 , 1582-4934
    URL: Issue
    URL: Article
    DOI: 10.1111/jcmm.v25.2
    DOI: 10.1111/jcmm.16119
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 2076114-4
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  • 6
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    Efficacy of early laparoscopic cholecystectomy compared with percutaneous transhepatic gallbladder drainage in treating acute calculous cholecystitis in elderly patients
    Informa UK Limited ; 2023
    In:  Acta Chirurgica Belgica
    Details
    In: Acta Chirurgica Belgica, Informa UK Limited
    Type of Medium: Online Resource
    ISSN: 0001-5458 , 2577-0160
    URL: Article
    DOI: 10.1080/00015458.2023.2232672
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 2023
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  • 7
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    Outcomes of reoperation for hepatolithiasis with 3D imaging individualized preoperative planning technique: a single-center experience
    Edizioni Minerva Medica ; 2021
    In:  Minerva Surgery Vol. 76, No. 1 ( 2021-03)
    Details
    In: Minerva Surgery, Edizioni Minerva Medica, Vol. 76, No. 1 ( 2021-03)
    Type of Medium: Online Resource
    ISSN: 2724-5691 , 2724-5438
    URL: Article
    DOI: 10.23736/S2724-5691.20.08250-4
    Language: English
    Publisher: Edizioni Minerva Medica
    Publication Date: 2021
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  • 8
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    Online Resource
    Role of procalcitonin as a predictor in difficult laparoscopic cholecystectomy for acute cholecystitis case: A retrospective study based on the TG18 criteria
    Springer Science and Business Media LLC ; 2019
    In:  Scientific Reports Vol. 9, No. 1 ( 2019-07-29)
    Details
    In: Scientific Reports, Springer Science and Business Media LLC, Vol. 9, No. 1 ( 2019-07-29)
    Abstract: Difficult laparoscopic cholecystectomy (DLC) is difficult to precisely predict before operation. This observational cohort study aimed to evaluate the predictive value of procalcitonin (PCT) for DLC in patients with acute cholecystitis (AC). A total of 115 patients were included in the study from January 2017 to April 2018. Multiple logistic regression and receiver-operating characteristic (ROC) were performed to evaluate the predictive value of PCT levels in DLC. Patients with DLC had significantly higher Tokyo Guidelines 2018 (TG18) grade ( P  = 0.002) and levels of C-reactive protein (CRP) ( P  = 0.007) and PCT ( P   〈  0.001). The cut-off value of PCT for predicting DLC was 1.50 ng/ml. The sensitivity and specificity were 91.3% (95% CI 78.3–97.1) and 76.8% (95% CI 64.8–85.8), respectively. The area under ROC curve was 92.7% (95% CI 88.2–97.3, P   〈  0.001). Our results suggested that PCT was a good predictor for DLC in the AC patients, but further research is necessary. Monitoring of PCT trends in AC patients may be useful for preoperative risk assessment.
    Type of Medium: Online Resource
    ISSN: 2045-2322
    URL: Article
    DOI: 10.1038/s41598-019-47501-0
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2019
    detail.hit.zdb_id: 2615211-3
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  • 9
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    Diagnostic accuracy of 3D imaging combined with intra-operative ultrasound in the prediction of post-hepatectomy liver failure
    AME Publishing Company ; 2022
    In:  Journal of Gastrointestinal Oncology Vol. 13, No. 3 ( 2022-6), p. 1224-1236
    Details
    In: Journal of Gastrointestinal Oncology, AME Publishing Company, Vol. 13, No. 3 ( 2022-6), p. 1224-1236
    Type of Medium: Online Resource
    ISSN: 2078-6891 , 2219-679X
    URL: Journal
    URL: Article
    DOI: 10.21037/jgo
    DOI: 10.21037/jgo-22-282
    Language: Unknown
    Publisher: AME Publishing Company
    Publication Date: 2022
    detail.hit.zdb_id: 2594644-4
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  • 10
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    Efficacy of extended view totally extra peritoneal approach versus laparoscopic intraperitoneal on lay mesh plus for abdominal wall hernias: a single center preliminary retrospective study
    Springer Science and Business Media LLC ; 2023
    In:  BMC Surgery Vol. 23, No. 1 ( 2023-07-13)
    Details
    In: BMC Surgery, Springer Science and Business Media LLC, Vol. 23, No. 1 ( 2023-07-13)
    Abstract: Laparoscopic minimally invasive surgery has become the primary treatment for ventral hernias. The laparoscopic intraperitoneal on lay mesh (IPOM) plus approach for abdominal wall hernias is the most used procedure, while extended view totally extraperitoneal (e‑TEP) repair is a newer option. This study aimed to compare the effectiveness and complications of the 2 procedures for abdominal wall hernias repair. Methods This was a retrospective and comparative single-center study done at The Second Clinical Medical College, Jinan University Hospital (Shenzhen People’s Hospital), Shenzhen, China. The study included patients with a 2 to 6 cm abdominal wall defect who underwent hernia repair from January 2022 to December 2022. Patients’ baseline characteristics, hernia features, operative time, blood loss, postoperative pain level, and total hospitalization expenses were extracted from the medical records and compared between patients who underwent the IPOM plus and e-TEP repair. Results A total of 53 patients were included: 22 in the e-TEP group and 31 in IPOM plus group. Patient demographic characteristics were similar between the 2 groups. The operation time of the e-TEP groups was significantly longer than the IPOM plus (98.5 ± 10.7 min vs. 65.9 ± 7.3 min, P   〈  0.01). Postoperative pain levels (VAS; visual analog scale) (4.2 ± 0.9 vs. 6.7 ± 0.9, P   〈  0.01), analgesic requirements (Tramadol) (25.0 ± 37.0 mg vs. 72.6 ± 40.5 mg, P   〈  0.01), length of hospital stay (1.2 ± 0.5days vs. 2.2 ± 0.6days, P   〈  0.01), and total hospitalization expenses (19695.9 ± 1221.7CNY vs. 35286.2 ± 1196.6CNY, P   〈  0.01) were significantly lower in the e-TEP group. The mean intraoperative blood loss was similar between the 2 groups. No postoperative complications were observed in either group. Conclusion The e-TEP approach for abdominal wall hernias appears to be better than IPOM plus with respect to postoperative pain levels (VAS: 4.2 ± 0.9 vs. 6.7 ± 0.9, P  〈  0.01) , analgesic requirements (25.0 ± 37.0 mg vs. 72.6 ± 40.5 mg, P  〈  0.01) , length of hospital stay (1.2 ± 0.5days vs. 2.2 ± 0.6days, P  〈  0.01) , and hospitalization costs (19695.9 ± 1221.7CNY vs. 35286.2 ± 1196.6CNY, P  〈  0.01) .
    Type of Medium: Online Resource
    ISSN: 1471-2482
    URL: Article
    DOI: 10.1186/s12893-023-02098-0
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 2050442-1
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