In:
PLOS ONE, Public Library of Science (PLoS), Vol. 16, No. 6 ( 2021-6-17), p. e0253219-
Abstract:
Subarachnoid hemorrhage (SAH) is a fatal stroke caused by bleeding in the brain. SAH can be caused by a ruptured aneurysm or head injury. One-third of patients will survive and recover. One-third will survive with disability; one-third will die. The focus of treatment is to stop bleeding, restore normal blood flow, and prevent vasospasm. Treatment for SAH varies, depending on the bleeding’s underlying cause and the extent of damage to the brain. Treatment may include lifesaving measures, symptom relief, repair of the bleeding vessel, and complication prevention. However, the useful diagnostic biomarkers of SAH are still limited due to the instability of gene marker expression. To overcome this limitation, we developed a new protocol pairing genes and screened significant gene pairs based on the feature selection algorithm. A classifier was constructed with the selected gene pairs and achieved a high performance.
Type of Medium:
Online Resource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0253219
DOI:
10.1371/journal.pone.0253219.g001
DOI:
10.1371/journal.pone.0253219.g002
DOI:
10.1371/journal.pone.0253219.g003
DOI:
10.1371/journal.pone.0253219.g004
DOI:
10.1371/journal.pone.0253219.g005
DOI:
10.1371/journal.pone.0253219.g006
DOI:
10.1371/journal.pone.0253219.g007
DOI:
10.1371/journal.pone.0253219.g008
DOI:
10.1371/journal.pone.0253219.g009
DOI:
10.1371/journal.pone.0253219.g010
DOI:
10.1371/journal.pone.0253219.g011
DOI:
10.1371/journal.pone.0253219.t001
DOI:
10.1371/journal.pone.0253219.s001
DOI:
10.1371/journal.pone.0253219.s002
DOI:
10.1371/journal.pone.0253219.s003
DOI:
10.1371/journal.pone.0253219.r001
DOI:
10.1371/journal.pone.0253219.r002
DOI:
10.1371/journal.pone.0253219.r003
DOI:
10.1371/journal.pone.0253219.r004
DOI:
10.1371/journal.pone.0253219.r005
DOI:
10.1371/journal.pone.0253219.r006
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2021
detail.hit.zdb_id:
2267670-3
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