In:
Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 146, No. Suppl_1 ( 2022-11-08)
Abstract:
Background: Lack of physical activity is associated with a higher risk of mortality and rehospitalization for patients with heart failure (HF). Although exercise is recommended to patients with HF to optimize health, engagement in physical activity (EPA) remains poor due to many barriers. There is limited knowledge about whether EPA is a unique predictor of event-free survival. Purpose: The purpose of this study was to determine whether EPA was an independent predictor of event-free survival in patients with HF controlling for demographic, clinical factors, and depressive symptoms. Method: We included 1135 patients with HF who completed a survey of EPA (Medical Outcomes Study Specific Adherence Scale [MOS-SAS]), depressive symptoms (Patient Health Questionnaire-9), and demographic and clinical characteristics (age, sex, smoking status, body mass index, and NYHA class). They were followed for 2-years. Event-free survival was the composite endpoint of time to all-cause hospitalization or death. Patients were categorized into EPA (stated engaged in physical activity at least once a week) and non-EPA (stated did not engage in physical activity at all) groups using an activity item of the MOS-SAS. Cox regression analysis was used to determine if EPA was an independent predictor of event-free survival. Result: Among patients (mean age = 64 ± 12.7 years, 64% male, 83% white, 44% NYHA class III/IV), 65% engaged in physical activity, while 35% did not. During follow-up, 118 deaths and 385 rehospitalizations occurred. Patients in the non-EPA group were 1.3 times more likely to die or be hospitalized compared with patients in the EPA group (HR =1.255, 95% CI: 1.039 - 1.517). Conclusion: We found that EPA, even at a low level (at least once a week) was beneficial in reducing the risk of mortality and hospitalization events. Innovative interventions should be developed to motivate non-EPA patients to engage in physical activity.
Type of Medium:
Online Resource
ISSN:
0009-7322
,
1524-4539
DOI:
10.1161/circ.146.suppl_1.11836
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2022
detail.hit.zdb_id:
1466401-X
Bookmarklink